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Entry Information
Entry status
(1)
Experimental methods
(2)
X-ray diffraction
(174)
Electron Microscopy
(4)
Authors
(446)
Lolis E
(50)
Whitman CP
(40)
Bucala R
(34)
Lolis EJ
(32)
Hackert ML
(28)
Pantouris G
(28)
Johnson WH
(23)
Fan C
(20)
Bhandari V
(19)
Poelarends GJ
(19)
Leng L
(18)
Rajasekaran D
(17)
Syed MA
(16)
Jorgensen WL
(15)
Serrano H
(15)
Cho TY
(14)
Cisneros JA
(13)
Robertson MJ
(13)
Zhang Y
(13)
Almrud JJ
(12)
Crichlow GV
(12)
Johnson Jr WH
(12)
Han Z
(11)
Rosenberg EM
(11)
Choi YM
(9)
Czerwinski RM
(9)
Guo Y
(9)
Li H
(9)
Li Y
(9)
McLean LR
(9)
Thunnissen AM
(9)
Vaz RJ
(9)
Thunnissen AMWH
(8)
Krimmer SG
(7)
Lubetsky JB
(7)
Wang SC
(7)
Batista VS
(6)
Burks EA
(6)
Cappello M
(6)
Cho Y
(6)
Dijkstra BW
(6)
Geertsema EM
(6)
Hampton MB
(6)
Kern AD
(6)
McLean L
(6)
Poddar H
(6)
Rutledge MT
(6)
Taylor AB
(6)
Tyndall JDA
(6)
Wilbanks SM
(6)
Yeates TO
(6)
Al-Abed Y
(5)
Baas BJ
(5)
Dale EJ
(5)
Dasgupta R
(5)
Dziedzic P
(5)
Gamble AB
(5)
Gommans AL
(5)
Loria JP
(5)
Nakatani Y
(5)
Smith RAJ
(5)
Spencer ES
(5)
Tyndall JD
(5)
Vermeire JJ
(5)
Vo CT
(5)
Zierow S
(5)
Al Obaidi N
(4)
Aljabari B
(4)
Almo SC
(4)
Chamala S
(4)
Cheng KF
(4)
Dodson EJ
(4)
Du X
(4)
Evans B
(4)
Gizzi A
(4)
Gonen S
(4)
Gonen T
(4)
Hillerich B
(4)
Ho J
(4)
Kar A
(4)
Lafleur J
(4)
Liu Y
(4)
Mesecar AD
(4)
New York Structural Genomics Research Consortium (NYSGRC)
(4)
Pegan SD
(4)
Rahimi M
(4)
Seidel R
(4)
Shah D
(4)
Smith RA
(4)
Swaminathan S
(4)
Thunnissen A-MWH
(4)
Trivedi-Parmar V
(4)
Valhondo M
(4)
Villigas G
(4)
Zencheck W
(4)
Almrud J
(3)
Ashrafi A
(3)
Bernhagen J
(3)
Blake P
(3)
Borosch S
(3)
More...
Homo / hetero assembly
(2)
homo
(166)
hetero
(12)
Assembly composition
(2)
protein structure
(166)
protein/protein complex
(12)
Assembly polymer count
(6)
trimer
(136)
hexamer
(26)
dimer
(6)
24-mer
(5)
monomer
(4)
heptamer
(1)
Resolution distribution
1.0 - 1.5
(20)
1.5 - 2
(98)
2.0 - 2.5
(42)
2.5 - 3
(14)
3.0 - 3.5
(4)
Release year distribution
1995 - 2000
(12)
2000 - 2005
(17)
2005 - 2010
(49)
2010 - 2015
(79)
2015 - 2020
(55)
Journal
(37)
Biochemistry
(33)
To be published
(27)
Chem Biol
(14)
Bioorg Med Chem Lett
(11)
J Biol Chem
(11)
Proc Natl Acad Sci U S A
(7)
Bioorg Chem
(6)
Angew Chem Int Ed Engl
(4)
ChemMedChem
(4)
Eur J Med Chem
(4)
J Am Chem Soc
(4)
J Med Chem
(4)
Nat Commun
(4)
ACS Med Chem Lett
(3)
Acta Crystallogr D Biol Crystallogr
(3)
FASEB J
(3)
J Cell Mol Med
(3)
PLoS One
(3)
Thesis
(3)
Arch Biochem Biophys
(2)
Biochem Biophys Res Commun
(2)
Biochemistry (Mosc)
(2)
Cell Chem Biol
(2)
Chembiochem
(2)
J Struct Funct Genomics
(2)
Mol Immunol
(2)
Nature
(2)
Protein Sci
(2)
ACS Catal
(1)
Acta Crystallogr D Struct Biol
(1)
Acta Crystallogr Sect F Struct Biol Cryst Commun
(1)
Biochem J
(1)
Cancer Res
(1)
Int J Oncol
(1)
J Immunol
(1)
Nat Struct Biol
(1)
Sci Rep
(1)
Macromolecules
Organism superkingdom
(3)
Eukaryota
(115)
Bacteria
(62)
Archaea
(1)
Organism name
(41)
Homo sapiens
(93)
Pseudomonas putida
(13)
coryneform bacterium
(8)
Pseudomonas pavonaceae
(7)
Pseudomonas aeruginosa PAO1
(6)
Mus musculus
(4)
Ancylostoma ceylanicum
(3)
Corynebacterium glutamicum
(3)
Leishmania major
(3)
Bacillus subtilis
(2)
Escherichia coli K-12
(2)
Methylibium petroleiphilum PM1
(2)
Plasmodium falciparum
(2)
Plasmodium yoelii yoelii
(2)
Rhodococcus jostii RHA1
(2)
Archaeoglobus fulgidus DSM 4304
(1)
Aspergillus fumigatus Af293
(1)
Bordetella bronchiseptica RB50
(1)
Chloroflexus aurantiacus J-10-fl
(1)
Deinococcus radiodurans R1
(1)
Escherichia coli
(1)
Escherichia coli C
(1)
Giardia lamblia ATCC 50803
(1)
Haemophilus influenzae
(1)
Helicobacter pylori 26695
(1)
Helicobacter pylori J99
(1)
Nostoc sp. PCC 7120 = FACHB-418
(1)
Plasmodium berghei ANKA
(1)
Plasmodium falciparum 3D7
(1)
Prochlorococcus marinus str. MIT 9313
(1)
Pseudomonas aeruginosa
(1)
Pseudomonas sp. CF600
(1)
Rattus norvegicus
(1)
Sebaldella termitidis ATCC 33386
(1)
Staphylococcus aureus
(1)
Streptomyces achromogenes
(1)
Thermus thermophilus HB8
(1)
Toxoplasma gondii
(1)
Trichinella spiralis
(1)
Vibrio cholerae O1 biovar El Tor str. N16961
(1)
Xenopus laevis
(1)
Molecule name
(49)
L-dopachrome isomerase
(106)
L-dopachrome tautomerase
(106)
Phenylpyruvate tautomerase
(106)
Macrophage migration inhibitory factor
(99)
MIF
(96)
GIF
(91)
Glycosylation-inhibiting factor
(91)
4-oxalocrotonate tautomerase
(22)
2-hydroxymuconate tautomerase
(20)
Uncharacterized protein
(17)
4-OT
(16)
Tautomerase cis-CaaD-like domain-containing protein
(10)
5-carboxymethyl-2-hydroxymuconate isomerase
(8)
Macrophage migration inhibitory factor-like protein
(8)
D-dopachrome decarboxylase
(5)
D-dopachrome tautomerase
(5)
4-oxalocrotonate tautomerase-like domain-containing protein
(4)
Alpha-subunit of trans-3-chloroacrylic acid dehalogenase
(4)
Beta-subunit of trans-3-chloroacrylic acid dehalogenase
(4)
Cis-3-chloroacrylic acid dehalogenase
(4)
FG41 Malonate Semialdehyde Decarboxylase
(4)
Phenylpyruvate tautomerase II
(4)
DER6
(3)
Delayed early response protein 6
(3)
Malonate semialdehyde decarboxylase
(3)
Tautomerase PptA
(3)
(2Z,4E)-2-hydroxyhexa-2,4-dienedioate keto-enol isomerase
(2)
DUF1904 domain-containing protein
(2)
Probable tautomerase HP_0924
(2)
Tautomerase
(2)
4-oxalocrotonate tautomerase family enzyme
(1)
4-oxalocrotonate tautomerase, putative
(1)
5-carboxymethyl-2-hydroxymuconate Delta-isomerase
(1)
5-carboxymethyl-2-hydroxymuconate delta-isomerase
(1)
5-carboxymethyl-2-hydroxymuconic acid isomerase
(1)
Alr4568 protein
(1)
CHM isomerase
(1)
CHMI
(1)
Glutathione-binding 13 kDa protein
(1)
HYPOTHETICAL PROTEIN HI1388.1
(1)
MACROPHAGE MIGRATION INHIBITORY FACTOR
(1)
Macrophage migration inhibitory factor homolog
(1)
Possible ATLS1-like light-inducible protein
(1)
Probable tautomerase SAR1376
(1)
Putative 4-oxalocrotonate isomerase protein
(1)
Putative macrophage migration inhibitory factor
(1)
Putative tautomerase
(1)
Tautomerase enzyme
(1)
Uncharacterized protein HI_1388.1
(1)
Molecule type
(1)
Protein
(178)
Gene names
(48)
MIF
(89)
GLIF
(88)
MMIF
(88)
xylH
(13)
PA1966
(7)
DDT
(4)
Mif
(4)
caaD1
(4)
caaD2
(4)
cis-caaD
(4)
Cgl0062
(3)
JW1456
(3)
b1461
(3)
mif
(3)
msaD
(3)
pptA
(3)
ydcE
(3)
BSU37540
(2)
HP_0924
(2)
LMJF_33_1740
(2)
MIF1
(2)
RHA1_ro02670
(2)
ywhB
(2)
AFUA_3G03220
(1)
AF_0669
(1)
BB0738
(1)
Caur_1354
(1)
Caur_1358
(1)
DR_A0227
(1)
Ddt
(1)
GL50803_0012091
(1)
HI_1388.1
(1)
LMJF_33_1750
(1)
MIF2
(1)
Mpe_A2265
(1)
Mpe_A3323
(1)
PF3D7_1229400
(1)
PMT_0503
(1)
SAR1376
(1)
Sterm_0053
(1)
TGRH88_014810
(1)
TTHB242
(1)
VC_0714
(1)
alr4568
(1)
dmpI
(1)
hpaF
(1)
hpcD
(1)
tomN
(1)
Interacting Molecules
(7)
2-hydroxymuconate tautomerase
(5)
Cobalamin adenosyltransferase-like domain-containing protein
(3)
DARP14 - Subunit A with DARPin
(2)
4-oxalocrotonate tautomerase
(1)
4-oxalocrotonate tautomerase-like domain-containing protein
(1)
Subunit A-DARPin
(1)
superfolder GFP
(1)
Interacting ligands
(91)
SO4 : SULFATE ION
(93)
GOL : GLYCEROL
(46)
IPA : ISOPROPYL ALCOHOL
(36)
CL : CHLORIDE ION
(23)
NA : SODIUM ION
(6)
PO4 : PHOSPHATE ION
(6)
ACT : ACETATE ION
(5)
AVR : (2R)-2-amino-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridin-3-yl]propan-1-one
(3)
EDO : 1,2-ETHANEDIOL
(3)
ENO : 3-(4-HYDROXY-PHENYL)PYRUVIC ACID
(3)
FHC : 2-FLUORO-3-(4-HYDROXYPHENYL)-2E-PROPENEOATE
(3)
IMD : IMIDAZOLE
(3)
RW1 : 4-phenylpyrimidine
(3)
ZN : ZINC ION
(3)
9BE : N-benzylthioformamide
(2)
ACY : ACETIC ACID
(2)
CIT : CITRIC ACID
(2)
LE2 : N-(2-phenylethyl)thioformamide
(2)
NCO : COBALT HEXAMMINE(III)
(2)
PR6 : 3-chloro-3-oxopropanoic acid
(2)
0FI : N-phenylthioformamide
(1)
0IN : 7-(pyridin-3-ylmethyl)quinolin-8-ol
(1)
1Q1 : 1-[(5S)-3-(3-fluoro-4-hydroxyphenyl)-4,5-dihydro-1,2-oxazol-5-yl]propan-2-one
(1)
1Q2 : (4R,6Z)-6-(3-fluoro-4-hydroxyphenyl)-4-hydroxy-6-iminohexan-2-one
(1)
1X2 : 6-isothiocyanatohexylbenzene
(1)
1ZW : N-[(4-cyanophenyl)methyl]methanethioamide
(1)
2OE : 3-[(2-methyl-6-phenylpyridin-4-yl)oxy]phenol
(1)
2OK : 4-(3-methoxy-5-methylphenoxy)-2-(4-methoxyphenyl)-6-methylpyridine
(1)
31E : (Z)-[(furan-2-ylmethyl)imino]methanethiol
(1)
35J : N-(pyridin-3-ylmethyl)thioformamide
(1)
3E1 : N,N'-(6,6'-dihydroxybiphenyl-3,3'-diyl)diacetamide
(1)
3TW : 4-{4-[6-(2-methoxyethoxy)quinolin-2-yl]-1H-1,2,3-triazol-1-yl}phenol
(1)
3TX : 4-[4-(quinolin-2-yl)-1H-1,2,3-triazol-1-yl]phenol
(1)
428 : 2-(1-methylethyl)imidazo[1,2-b]pyridazin-6-ol
(1)
47X : 3-(3,4-dihydroxyphenyl)-7-hydroxy-4H-chromen-4-one
(1)
4MT : N-[2-(4-hydroxyphenyl)ethyl]thioformamide
(1)
65V : 3-({2-[1-(3-fluoro-4-hydroxyphenyl)-1H-1,2,3-triazol-4-yl]quinolin-5-yl}oxy)benzoic acid
(1)
6B9 : 2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)-5-[(E)-(sulfanylmethylidene)amino]benzoic acid
(1)
6DQ : 2-pyridin-3-yl-1,3-benzothiazin-4-one
(1)
6H1 : 6-{[4-(trifluoromethyl)phenyl]methyl}-2H-1,3-benzodioxol-5-ol
(1)
6H2 : 4-(imidazo[1,2-a]pyridin-2-yl)benzene-1,2-diol
(1)
6UV : (2~{R})-2-[[4-[[2,4-bis(azanyl)pteridin-6-yl]methyl-methyl-amino]phenyl]carbonylamino]pentanedioic acid
(1)
6Y5 : 5-fluoranyl-2-oxidanylidene-pentanoic acid
(1)
7DH : (3E)-5-hydroxy-2-oxopent-3-enoic acid
(1)
7L9 : 4-(3-carboxyphenyl)pyridine-2,5-dicarboxylic acid
(1)
88X : 5-ethyl-2-(phenylcarbonyl)imidazo[1,2-a]pyrimidin-7(1H)-one
(1)
956 : 1-methyl-2-oxo-4-[4-(thiophen-2-ylcarbonyl)piperazin-1-yl]-1,2-dihydroquinoline-3-carbonitrile
(1)
9AI : N-prop-2-en-1-ylthioformamide
(1)
AVL : 2-methyl-1-[2-(propan-2-yl)pyrazolo[1,5-a]pyridin-3-yl]propan-1-one
(1)
B3P : 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
(1)
BEZ : BENZOIC ACID
(1)
C9G : 2-[1-(4-hydroxyphenyl)-1H-1,2,3-triazol-4-yl]-7-methyl-1,7-naphthyridin-8(7H)-one
(1)
C9J : 2-[1-(3-fluoro-4-hydroxyphenyl)-1H-1,2,3-triazol-4-yl]-7-methyl-1,7-naphthyridin-8(7H)-one
(1)
C9Y : {2-[1-(3-fluoro-4-hydroxyphenyl)-1H-1,2,3-triazol-4-yl]-8-oxo-1,7-naphthyridin-7(8H)-yl}acetic acid
(1)
CA : CALCIUM ION
(1)
DHC : CAFFEIC ACID
(1)
DIO : 1,4-DIETHYLENE DIOXIDE
(1)
DMF : DIMETHYLFORMAMIDE
(1)
EN1 : (2E)-2-hydroxy-3-(4-hydroxyphenyl)prop-2-enoic acid
(1)
EPE : 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
(1)
EV7 : 2-[(naphthalen-2-yl)oxy]-5-(1H-pyrazol-4-yl)benzoic acid
(1)
EWD : 2-phenoxy-5-(1H-pyrazol-4-yl)benzoic acid
(1)
EWG : 3-(1H-pyrazol-4-yl)benzoic acid
(1)
EWJ : 5-(3-fluoro-1H-pyrazol-4-yl)-2-[(naphthalen-2-yl)oxy]benzoic acid
(1)
FMT : FORMIC ACID
(1)
FUN : 5-(AMINOSULFONYL)-4-CHLORO-2-[(2-FURYLMETHYL)AMINO]BENZOIC ACID
(1)
FUZ : 2-[(furan-2-ylmethyl)amino]benzoic acid
(1)
GLU : GLUTAMIC ACID
(1)
HBX : benzaldehyde
(1)
HDI : 3-(4-HYDROXYPHENYL)-4,5-DIHYDRO-5-ISOXAZOLE-ACETIC ACID METHYL ESTER
(1)
LAC : LACTIC ACID
(1)
LE3 : N-{4-[(R)-methylsulfinyl]butyl}thioformamide
(1)
MG : MAGNESIUM ION
(1)
MLA : MALONIC ACID
(1)
MLI : MALONATE ION
(1)
NO3 : NITRATE ION
(1)
NS8 : trans beta nitrostyrene
(1)
NVS : 7-hydroxy-3-(4-methoxyphenyl)-3,4-dihydro-2H-1,3-benzoxazin-2-one
(1)
OX3 : 4-HYDROXYBENZALDEHYDE O-(CYCLOHEXYLCARBONYL)OXIME
(1)
OX4 : 3-FLUORO-4-HYDROXYBENZALDEHYDE O-(CYCLOHEXYLCARBONYL)OXIME
(1)
OX5 : 4-HYDROXYBENZALDEHYDE O-(3,3-DIMETHYLBUTANOYL)OXIME
(1)
OXP : 2-OXO-3-PENTENOIC ACID
(1)
PEG : DI(HYDROXYETHYL)ETHER
(1)
PMS : phenylmethanesulfonic acid
(1)
TLA : L(+)-TARTARIC ACID
(1)
TRS : 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
(1)
XV1 : 7-(2-fluorobenzyl)quinolin-8-ol
(1)
Y0X : 6,6'-[(3,3'-dimethoxybiphenyl-4,4'-diyl)di(E)diazene-2,1-diyl]bis(4-amino-5-hydroxynaphthalene-1,3-disulfonic acid)
(1)
YZ9 : 7-HYDROXY-2-OXO-CHROMENE-3-CARBOXYLIC ACID ETHYL ESTER
(1)
ZEC : 6-HYDROXY-1,3-BENZOTHIAZOLE-2-SULFONAMIDE
(1)
ZIN : 7-(pyridin-2-ylmethyl)quinolin-8-ol
(1)
Function and Biology
EC number / name
(6)
5.3.2.1 : Phenylpyruvate tautomerase
(106)
5.3.3.12 : L-dopachrome isomerase
(106)
5.3.2.6 : 2-hydroxymuconate tautomerase
(20)
4.1.1.84 : D-dopachrome decarboxylase
(5)
5.3.2.2 : Oxaloacetate tautomerase
(3)
5.3.3.10 : 5-carboxymethyl-2-hydroxymuconate Delta-isomerase
(2)
Biological function
(19)
isomerase activity
(141)
phenylpyruvate tautomerase activity
(113)
cytokine activity
(109)
dopachrome isomerase activity
(100)
cytokine receptor binding
(99)
protease binding
(93)
chemoattractant activity
(92)
identical protein binding
(92)
protein binding
(88)
5-carboxymethyl-2-hydroxymuconate delta-isomerase activity
(10)
D-dopachrome decarboxylase activity
(5)
lyase activity
(5)
metal ion binding
(5)
intramolecular oxidoreductase activity, interconverting keto- and enol-groups
(3)
protein homodimerization activity
(3)
molecular_function
(2)
host cell surface receptor binding
(1)
oxidoreductase activity
(1)
protein-containing complex binding
(1)
Biological process
(70)
negative regulation of macrophage chemotaxis
(96)
positive regulation of ERK1 and ERK2 cascade
(96)
positive regulation of tumor necrosis factor production
(96)
immune system process
(94)
inflammatory response
(94)
innate immune response
(94)
DNA damage response, signal transduction by p53 class mediator
(92)
carboxylic acid metabolic process
(92)
cell surface receptor signaling pathway
(92)
cellular senescence
(92)
negative regulation of DNA damage response, signal transduction by p53 class mediator
(92)
negative regulation of apoptotic process
(92)
negative regulation of cell migration
(92)
negative regulation of cellular senescence
(92)
negative regulation of gene expression
(92)
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
(92)
negative regulation of mature B cell apoptotic process
(92)
negative regulation of myeloid cell apoptotic process
(92)
negative regulation of protein metabolic process
(92)
positive chemotaxis
(92)
positive regulation of B cell proliferation
(92)
positive regulation of arachidonate secretion
(92)
positive regulation of cAMP/PKA signal transduction
(92)
positive regulation of cell population proliferation
(92)
positive regulation of chemokine (C-X-C motif) ligand 2 production
(92)
positive regulation of cytokine production
(92)
positive regulation of fibroblast proliferation
(92)
positive regulation of lipopolysaccharide-mediated signaling pathway
(92)
positive regulation of myeloid leukocyte cytokine production involved in immune response
(92)
positive regulation of phosphorylation
(92)
positive regulation of prostaglandin secretion involved in immune response
(92)
prostaglandin biosynthetic process
(92)
protein homotrimerization
(92)
regulation of cell population proliferation
(92)
regulation of macrophage activation
(88)
catabolic process
(24)
signal transduction
(17)
toluene catabolic process
(14)
xylene catabolic process
(13)
melanin biosynthetic process
(5)
positive regulation of inflammatory response
(5)
positive regulation of adaptive immune response
(3)
biological_process
(2)
adhesion of symbiont to host cell surface via host glycoprotein
(1)
brain renin-angiotensin system
(1)
cellular response to hydrogen peroxide
(1)
cellular response to hypoxia
(1)
drinking behavior
(1)
hair follicle development
(1)
positive regulation of D-glucose import
(1)
positive regulation of acute inflammatory response
(1)
positive regulation of axon regeneration
(1)
positive regulation of glycolytic process
(1)
positive regulation of immune response
(1)
positive regulation of potassium ion transport
(1)
positive regulation of smooth muscle cell migration
(1)
response to estradiol
(1)
response to glucocorticoid
(1)
response to hormone
(1)
response to insulin
(1)
response to lipopolysaccharide
(1)
response to mechanical stimulus
(1)
response to menaquinone
(1)
response to progesterone
(1)
response to vitamin E
(1)
response to xenobiotic stimulus
(1)
skin development
(1)
spermatogenesis
(1)
symbiont-mediated evasion of host immune response
(1)
symbiont-mediated suppression of host toll-like receptor signaling pathway
(1)
Biological cell component
(15)
extracellular space
(114)
extracellular region
(106)
cytoplasm
(103)
cell surface
(92)
extracellular exosome
(92)
plasma membrane
(92)
cytosol
(91)
nucleoplasm
(91)
ficolin-1-rich granule lumen
(88)
secretory granule lumen
(88)
vesicle
(88)
myelin sheath
(3)
cellular_component
(2)
Maurer's cleft
(1)
host cell cytoplasm
(1)
Sequence and Structure classification
SCOP fold
(1)
Tautomerase/MIF
(34)
SCOP family
(6)
MIF-related
(19)
4-oxalocrotonate tautomerase-like
(9)
MSAD-like
(3)
5-carboxymethyl-2-hydroxymuconate isomerase (CHMI)
(1)
Hypothetical protein HI1388.1
(1)
VC0714-like
(1)
CATH class
(1)
Alpha Beta
(178)
CATH topology
(1)
Macrophage Migration Inhibitory Factor
(178)
Pfam accession / name
(7)
PF01187 : MIF
(114)
PF01361 : Tautomerase
(32)
PF02962 : CHMI
(10)
PF14832 : Tautomerase_3
(10)
PF14552 : Tautomerase_2
(9)
PF08921 : DUF1904
(2)
PF21420 : Tautomerase-like
(1)
Experimental Information
Diffraction protocol
(2)
Single wavelength
(166)
MAD
(2)
Diffraction radiation source type
(3)
Rotating anode
(100)
Synchrotron
(70)
Sealed tube
(1)
Diffraction source
(48)
RIGAKU
(32)
RIGAKU RU200
(22)
RIGAKU MICROMAX-007 HF
(15)
NSLS BEAMLINE X29A
(13)
RIGAKU RUH3R
(11)
RIGAKU MICROMAX-007
(9)
NSLS BEAMLINE X25
(7)
APS BEAMLINE 22-ID
(3)
APS BEAMLINE 24-ID-C
(3)
AUSTRALIAN SYNCHROTRON BEAMLINE MX1
(3)
BRUKER AXS MICROSTAR
(3)
ESRF BEAMLINE BM14
(3)
PHOTON FACTORY BEAMLINE BL-6B
(3)
ALS BEAMLINE 5.0.3
(2)
APS BEAMLINE 19-ID
(2)
APS BEAMLINE 22-BM
(2)
APS BEAMLINE 24-ID-E
(2)
BSRF BEAMLINE 3W1A
(2)
ESRF BEAMLINE ID14-4
(2)
ESRF BEAMLINE ID23-2
(2)
RIGAKU RUH2R
(2)
SLS BEAMLINE X06SA
(2)
ALS BEAMLINE 8.2.1
(1)
ALS BEAMLINE 8.3.1
(1)
APS BEAMLINE 14-BM-D
(1)
APS BEAMLINE 17-ID
(1)
APS BEAMLINE 19-BM
(1)
APS BEAMLINE 23-ID-B
(1)
APS BEAMLINE 23-ID-D
(1)
Cu FINE FOCUS
(1)
DIAMOND BEAMLINE I03
(1)
DIAMOND BEAMLINE I04
(1)
EMBL/DESY, HAMBURG BEAMLINE X11
(1)
ENRAF-NONIUS
(1)
ENRAF-NONIUS FR591
(1)
ESRF BEAMLINE ID14-1
(1)
ESRF BEAMLINE ID14-2
(1)
ESRF BEAMLINE ID14-3
(1)
ESRF BEAMLINE ID29
(1)
OTHER
(1)
OXFORD DIFFRACTION ENHANCE ULTRA
(1)
PETRA III, DESY BEAMLINE P11
(1)
PETRA III, EMBL c/o DESY BEAMLINE P14 (MX2)
(1)
PHOTON FACTORY BEAMLINE BL-6A
(1)
RIGAKU RU300
(1)
SLS BEAMLINE X06DA
(1)
SPRING-8 BEAMLINE BL32B2
(1)
SPRING-8 BEAMLINE BL41XU
(1)
Synchrotron site
(13)
NSLS
(20)
APS
(17)
ESRF
(11)
ALS
(4)
Photon Factory
(4)
Australian Synchrotron
(3)
SLS
(3)
BSRF
(2)
Diamond
(2)
SPring-8
(2)
EMBL/DESY, Hamburg
(1)
PETRA III, DESY
(1)
PETRA III, EMBL c/o DESY
(1)
Diffraction detector type
(5)
Image plate
(77)
CCD
(55)
Pixel
(31)
Area detector
(3)
Diffractometer
(2)
Refinement software
(7)
REFMAC
(97)
CNS
(31)
PHENIX
(28)
X-PLOR
(18)
CNX
(11)
PROLSQ
(2)
SHELXL-97
(1)
EM microscope model
(1)
FEI TITAN KRIOS
(4)
EM detector name
(1)
GATAN K2 SUMMIT (4k x 4k)
(4)
Representative Structures
Representative Structures
Entries
Macromolecules
Compounds
Protein families
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Entries 1 to 10 of 178
Select all entries on this page
Crystal Structure of Macrophage Migration Inhibitory Factor (MIF) with a Biaryltriazole Inhibitor (3i-305)
Robertson MJ, Jorgensen WL
J Am Chem Soc
(2016)
[PMID: 27299179 ]
Source organism: Homo sapiens
Assembly composition: protein only structure
Assembly name:
Macrophage migration inhibitory factor
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-146863 (Preferred)
search this ID

Crystal structure of H62A mutant of human macrophage migration inhibitory factor
Pantouris G, Lolis E
Cell Chem Biol
(2020)
[PMID: 32433911 ]
Source organism: Homo sapiens
Assembly composition: protein only structure
Assembly name:
Macrophage migration inhibitory factor
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-146863 (Preferred)
search this ID

Macrophage Migration Inhibitory Factor bound to Inhibitor K664 Derivative
Robertson MJ, Jorgensen WL
Bioorg Med Chem Lett
(2016)
[PMID: 27156768 ]
Source organism: Homo sapiens
Assembly composition: protein only structure
Assembly name:
Macrophage migration inhibitory factor
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-146863 (Preferred)
search this ID

Crystal Structure of Macrophage Migration Inhibitory Factor (MIF) with a Potent Inhibitor (NVS-2)
Robertson MJ, Jorgensen WL
J Am Chem Soc
(2016)
[PMID: 27299179 ]
Source organism: Homo sapiens
Assembly composition: protein only structure
Assembly name:
Macrophage migration inhibitory factor
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-146863 (Preferred)
search this ID

Crystal structure of N97A mutant of human macrophage migration inhibitory factor
Pantouris G, Lolis E
Angew Chem Int Ed Engl
(2018)
[PMID: 29669180 ]
Source organism: Homo sapiens
Assembly composition: protein only structure
Assembly name:
Macrophage migration inhibitory factor
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-146863 (Preferred)
search this ID

Crystal structure of N102A mutant of human macrophage migration inhibitory factor
Pantouris G, Lolis E
To be published
Source organism: Homo sapiens
Assembly composition: protein only structure
Assembly name:
Macrophage migration inhibitory factor
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-146863 (Preferred)
search this ID

Macrophage Migration Inhibitory Factor in Complex with a Pyrazole Inhibitor (5)
Robertson MJ, Krimmer SG, Jorgensen WL
ChemMedChem
(2018)
[PMID: 29575754 ]
Source organism: Homo sapiens
Assembly composition: protein only structure
Assembly name:
Macrophage migration inhibitory factor
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-146863 (Preferred)
search this ID

Crystal structure of Y99A mutant of human macrophage migration inhibitory factor
Pantouris G, Lolis E
Angew Chem Int Ed Engl
(2018)
[PMID: 29669180 ]
Source organism: Homo sapiens
Assembly composition: protein only structure
Assembly name:
Macrophage migration inhibitory factor
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-146863 (Preferred)
search this ID

CRYSTAL STRUCTURE OF 4-OXALOCROTONATE TAUTOMERASE INACTIVATED BY BrHPD
Zhang Y, Li W, Stack T
Biochemistry
(2018)
[PMID: 29303557 ]
Source organism: Pseudomonas putida
Assembly composition: protein only structure
Assembly name:
2-hydroxymuconate tautomerase
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-169566 (Preferred)
search this ID

Crystal structure of N109A mutant of human macrophage migration inhibitory factor
Pantouris G, Lolis E
Chem Biol
(2015)
[PMID: 26364929 ]
Source organism: Homo sapiens
Assembly composition: protein only structure
Assembly name:
Macrophage migration inhibitory factor
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-146863 (Preferred)
search this ID

...
Entries 1 to 10 of 178