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Entry Information
Entry status
(1)
Experimental methods
(1)
X-ray diffraction
(41)
Authors
(104)
Funasaka T
(11)
Haga A
(11)
Nagase H
(11)
Nakamura KT
(11)
Raz A
(11)
Tanaka N
(11)
Hashimoto K
(9)
Kusakabe Y
(9)
Naba N
(9)
Shiraiwa K
(9)
Davies C
(8)
Jeffery CJ
(8)
Muirhead H
(8)
Anderson WF
(5)
Center for Structural Genomics of Infectious Diseases (CSGID)
(5)
Chirgwin J
(5)
Arsenieva D
(4)
Hasseman J
(4)
Joachimiak A
(4)
Maltseva N
(4)
Osipiuk J
(4)
Burns S
(3)
Cordeiro AT
(3)
Graham Solomons JT
(3)
Hardre R
(3)
Krings S
(3)
Krishnamurthy N
(3)
Salmon L
(3)
Solomons JT
(3)
Solomons JTG
(3)
Swan MK
(3)
Thiemann OH
(3)
Zimmerly EM
(3)
Akiyama H
(2)
Appavu BL
(2)
Arrowsmith CH
(2)
Bountra C
(2)
Cossar D
(2)
Delboni LF
(2)
Edwards AM
(2)
Gileadi T
(2)
Hills T
(2)
Hui R
(2)
Hutchinson A
(2)
Lee JH
(2)
Lew J
(2)
Mazock GH
(2)
Michels PA
(2)
Pizarro JC
(2)
Seattle Structural Genomics Center for Infectious Disease (SSGCID)
(2)
Structural Genomics Consortium (SGC)
(2)
Uemura H
(2)
Weadge J
(2)
Weigelt J
(2)
Wernimont AK
(2)
Alber T
(1)
Anand K
(1)
Anant A
(1)
Arsenieva DA
(1)
Bahnson BJ
(1)
Berger JM
(1)
Chang KZ
(1)
Chien W
(1)
Clifton MC
(1)
Davies D
(1)
Dubrovska I
(1)
Echols N
(1)
Edwards TE
(1)
Gardberg A
(1)
Garg LC
(1)
Garratt RC
(1)
Gee CL
(1)
Godoi PH
(1)
Godoi PHC
(1)
Gradia S
(1)
Halavaty A
(1)
Hardré R
(1)
Iavarone AT
(1)
Jeffrey CJ
(1)
Li X
(1)
Mathur D
(1)
May A
(1)
May AP
(1)
Michels PAM
(1)
Minasov G
(1)
Moskaleva A
(1)
Nanao M
(1)
Oliva G
(1)
Papazisi L
(1)
Patel V
(1)
Pearce J
(1)
Petsko GA
(1)
Read J
(1)
Read JA
(1)
Ringe D
(1)
Shuvalova L
(1)
Silva CH
(1)
Silva CHTP
(1)
Staker B
(1)
Stewart L
(1)
More...
Homo / hetero assembly
(1)
homo
(41)
Assembly composition
(1)
protein structure
(41)
Assembly polymer count
(1)
dimer
(41)
Resolution distribution
1.0 - 1.5
(6)
1.5 - 2
(21)
2.0 - 2.5
(11)
2.5 - 3
(2)
3.5 - 4
(1)
Release year distribution
1995 - 2000
(1)
2000 - 2005
(19)
2005 - 2010
(16)
2010 - 2015
(9)
Journal
(11)
J Mol Biol
(16)
To be published
(9)
Proteins
(4)
Biochemistry
(3)
Acta Crystallogr D Biol Crystallogr
(2)
Eur J Biochem
(2)
Acta Crystallogr Sect F Struct Biol Cryst Commun
(1)
Biochim Biophys Acta
(1)
PLoS One
(1)
Proc Natl Acad Sci U S A
(1)
Protein Sci
(1)
Macromolecules
Organism superkingdom
(2)
Eukaryota
(33)
Bacteria
(8)
Organism name
(15)
Mus musculus
(12)
Oryctolagus cuniculus
(7)
Homo sapiens
(5)
Francisella tularensis subsp. tularensis
(2)
Francisella tularensis subsp. tularensis SCHU S4
(2)
Plasmodium falciparum 3D7
(2)
Sus scrofa
(2)
Trypanosoma brucei brucei
(2)
Brucella melitensis bv. 1 str. 16M
(1)
Escherichia coli DH5[alpha]
(1)
Leishmania mexicana
(1)
Leishmania mexicana mexicana
(1)
Mycobacterium tuberculosis H37Rv
(1)
Toxoplasma gondii
(1)
Vibrio cholerae
(1)
Molecule name
(13)
Glucose-6-phosphate isomerase
(39)
GPI
(38)
PGI
(38)
PHI
(38)
Phosphoglucose isomerase
(38)
Phosphohexose isomerase
(38)
AMF
(26)
Autocrine motility factor
(26)
NLK
(26)
Neuroleukin
(26)
SA-36
(5)
Sperm antigen 36
(5)
Glucose-6-phosphate isomerase, glycosomal
(2)
Molecule type
(1)
Protein
(41)
Gene names
(13)
GPI
(14)
Gpi
(12)
Gpi1
(12)
pgi
(8)
FTT_1315c
(4)
PGI
(4)
PF3D7_1436000
(2)
BMEI1636
(1)
JW3985
(1)
MTCY10D7.28
(1)
Rv0946c
(1)
VC_0374
(1)
b4025
(1)
Interacting ligands
(25)
GOL : GLYCEROL
(16)
SO4 : SULFATE ION
(7)
F6P : 6-O-phosphono-beta-D-fructofuranose
(6)
PO4 : PHOSPHATE ION
(6)
CA : CALCIUM ION
(5)
BME : BETA-MERCAPTOETHANOL
(4)
CL : CHLORIDE ION
(4)
6PG : 6-PHOSPHOGLUCONIC ACID
(3)
G6Q : GLUCOSE-6-PHOSPHATE
(3)
IPA : ISOPROPYL ALCOHOL
(3)
MES : 2-(N-MORPHOLINO)-ETHANESULFONIC ACID
(3)
PA5 : 5-PHOSPHOARABINONIC ACID
(3)
E4P : ERYTHOSE-4-PHOSPHATE
(2)
S6P : D-SORBITOL-6-PHOSPHATE
(2)
A5P : ARABINOSE-5-PHOSPHATE
(1)
ACT : ACETATE ION
(1)
CIT : CITRIC ACID
(1)
DER : D-4-PHOSPHOERYTHRONIC ACID
(1)
EDO : 1,2-ETHANEDIOL
(1)
G6P : 6-O-phosphono-alpha-D-glucopyranose
(1)
NA : SODIUM ION
(1)
PAN : 5-PHOSPHO-D-ARABINOHYDROXAMIC ACID
(1)
PEG : DI(HYDROXYETHYL)ETHER
(1)
PG4 : TETRAETHYLENE GLYCOL
(1)
RI2 : 1,5-di-O-phosphono-alpha-D-ribofuranose
(1)
Function and Biology
EC number / name
(1)
5.3.1.9 : Glucose-6-phosphate isomerase
(40)
Biological function
(10)
carbohydrate derivative binding
(41)
glucose-6-phosphate isomerase activity
(41)
isomerase activity
(40)
monosaccharide binding
(40)
cytokine activity
(26)
ubiquitin protein ligase binding
(19)
growth factor activity
(17)
protein binding
(17)
identical protein binding
(1)
protein homodimerization activity
(1)
Biological process
(27)
carbohydrate derivative metabolic process
(41)
gluconeogenesis
(41)
glycolytic process
(41)
glucose 6-phosphate metabolic process
(40)
signal transduction
(26)
canonical glycolysis
(19)
erythrocyte homeostasis
(19)
fructose 6-phosphate metabolic process
(19)
glucose homeostasis
(19)
in utero embryonic development
(19)
mesoderm formation
(19)
positive regulation of endothelial cell migration
(19)
positive regulation of immunoglobulin production
(19)
learning or memory
(17)
negative regulation of apoptotic process
(17)
response to cadmium ion
(17)
response to estradiol
(17)
response to immobilization stress
(17)
response to muscle stretch
(17)
response to progesterone
(17)
response to testosterone
(17)
glycolytic process through glucose-6-phosphate
(12)
carbohydrate metabolic process
(5)
hemostasis
(5)
humoral immune response
(5)
pentose-phosphate shunt
(2)
cellular response to oxidative stress
(1)
Biological cell component
(13)
cytosol
(40)
cytoplasm
(36)
extracellular region
(26)
extracellular space
(26)
plasma membrane
(20)
ciliary membrane
(19)
myelin sheath
(12)
extracellular exosome
(5)
ficolin-1-rich granule lumen
(5)
membrane
(5)
secretory granule lumen
(5)
glycosome
(2)
peroxisome
(2)
Sequence and Structure classification
SCOP fold
(1)
SIS domain
(19)
SCOP family
(1)
Phosphoglucose isomerase, PGI
(19)
CATH class
(2)
Alpha Beta
(41)
Mainly Alpha
(41)
CATH topology
(2)
Phosphoglucose isomerase, C-terminal domain
(41)
Rossmann fold
(41)
Pfam accession / name
(1)
PF00342 : PGI
(40)
Experimental Information
Diffraction protocol
(2)
Single wavelength
(40)
MAD
(1)
Diffraction radiation source type
(2)
Synchrotron
(33)
Rotating anode
(8)
Diffraction source
(26)
APS BEAMLINE 14-BM-C
(4)
PHOTON FACTORY BEAMLINE BL-6A
(4)
APS BEAMLINE 22-ID
(3)
RIGAKU RU300
(3)
APS BEAMLINE 19-BM
(2)
APS BEAMLINE 19-ID
(2)
APS BEAMLINE 21-ID-F
(2)
PHOTON FACTORY BEAMLINE AR-NW12A
(2)
SPRING-8 BEAMLINE BL38B1
(2)
ALS BEAMLINE 8.3.1
(1)
APS BEAMLINE 22-BM
(1)
CLSI BEAMLINE 08ID-1
(1)
ELLIOT
(1)
ESRF BEAMLINE ID29
(1)
LNLS BEAMLINE D03B-MX1
(1)
NSLS BEAMLINE X12B
(1)
NSLS BEAMLINE X25
(1)
PHOTON FACTORY BEAMLINE BL-18B
(1)
PHOTON FACTORY BEAMLINE BL-5A
(1)
RIGAKU
(1)
RIGAKU FR-E SUPERBRIGHT
(1)
RIGAKU MICROMAX-007
(1)
RIGAKU RU200
(1)
SPRING-8 BEAMLINE BL41XU
(1)
SRS
(1)
SRS BEAMLINE PX7.2
(1)
Synchrotron site
(9)
APS
(14)
Photon Factory
(8)
SPring-8
(3)
NSLS
(2)
SRS
(2)
ALS
(1)
CLSI
(1)
ESRF
(1)
LNLS
(1)
Diffraction detector type
(5)
CCD
(29)
Image plate
(9)
Area detector
(1)
Diffractometer
(1)
Film
(1)
Refinement software
(6)
REFMAC
(30)
CNS
(10)
BUSTER
(2)
BUSTER-TNT
(2)
PHENIX
(1)
XTALVIEW
(1)
Representative Structures
Representative Structures
Entries
Macromolecules
Compounds
Protein families
Entries 1 to 10 of 41
Select all entries on this page
Crystal structure of mouse AMF
Tanaka N, Haga A, Naba N, Shiraiwa K, Kusakabe Y, Hashimoto K, Funasaka T, Nagase H, Raz A, Nakamura KT
J Mol Biol
(2006)
[PMID: 16375918 ]
Source organism: Mus musculus
Assembly composition: protein only structure
Assembly name:
Glucose-6-phosphate isomerase
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-139199 (Preferred)
search this ID

Crystal structure of mouse AMF / F6P complex
Tanaka N, Haga A, Naba N, Shiraiwa K, Kusakabe Y, Hashimoto K, Funasaka T, Nagase H, Raz A, Nakamura KT
J Mol Biol
(2006)
[PMID: 16375918 ]
Source organism: Mus musculus
Assembly composition: protein only structure
Assembly name:
Glucose-6-phosphate isomerase
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-139199 (Preferred)
search this ID

Crystal structure of mouse AMF / F6P complex
Tanaka N, Haga A, Naba N, Shiraiwa K, Kusakabe Y, Hashimoto K, Funasaka T, Nagase H, Raz A, Nakamura KT
J Mol Biol
(2006)
[PMID: 16375918 ]
Source organism: Mus musculus
Assembly composition: protein only structure
Assembly name:
Glucose-6-phosphate isomerase
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-139199 (Preferred)
search this ID

Crystal structure of mouse AMF / A5P complex
Tanaka N, Haga A, Naba N, Shiraiwa K, Kusakabe Y, Hashimoto K, Funasaka T, Nagase H, Raz A, Nakamura KT
J Mol Biol
(2006)
[PMID: 16375918 ]
Source organism: Mus musculus
Assembly composition: protein only structure
Assembly name:
Glucose-6-phosphate isomerase
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-139199 (Preferred)
search this ID

The structure of Glucose-6-phosphate isomerase (GPI) from Brucella melitensis
Seattle Structural Genomics Center for Infectious Disease (SSGCID)
To be published
Source organism: Brucella melitensis bv. 1 str. 16M
Assembly composition: protein only structure
Assembly name:
Glucose-6-phosphate isomerase
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-187046 (Preferred)
search this ID

Crystal structure of phosphoglucose isomerase from T. brucei containing glucose-6-phosphate in the active site
Arsenieva D, Mazock GH, Appavu BL, Jeffery CJ
Proteins
(2009)
[PMID: 18561188 ]
Source organism: Trypanosoma brucei brucei
Assembly composition: protein only structure
Assembly name:
Glucose-6-phosphate isomerase, glycosomal
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-146553 (Preferred)
search this ID

Crystal structure of mouse AMF / S6P complex
Tanaka N, Haga A, Naba N, Shiraiwa K, Kusakabe Y, Hashimoto K, Funasaka T, Nagase H, Raz A, Nakamura KT
J Mol Biol
(2006)
[PMID: 16375918 ]
Source organism: Mus musculus
Assembly composition: protein only structure
Assembly name:
Glucose-6-phosphate isomerase
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-139199 (Preferred)
search this ID

Crystal structure of Glucose-6-Phosphate Isomerase (PF14_0341) from Plasmodium falciparum 3D7
Gileadi T, Wernimont AK, Hutchinson A, Weadge J, Cossar D, Lew J, Arrowsmith CH, Edwards AM, Bountra C, Weigelt J, Hui R, Hills T, Pizarro JC, Structural Genomics Consortium (SGC)
To be published
Source organism: Plasmodium falciparum 3D7
Assembly composition: protein only structure
Assembly name:
Glucose-6-phosphate isomerase
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-184815 (Preferred)
search this ID

Glucose-6-phosphate isomerase from Francisella tularensis complexed with ribose 1,5-bisphosphate.
Osipiuk J, Maltseva N, Hasseman J, Anderson WF, Joachimiak A, Center for Structural Genomics of Infectious Diseases (CSGID)
To be published
Source organism: Francisella tularensis subsp. tularensis SCHU S4
Assembly composition: protein only structure
Assembly name:
Glucose-6-phosphate isomerase
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-177662 (Preferred)
search this ID

Crystal structure of mouse AMF / E4P complex
Tanaka N, Haga A, Naba N, Shiraiwa K, Kusakabe Y, Hashimoto K, Funasaka T, Nagase H, Raz A, Nakamura KT
J Mol Biol
(2006)
[PMID: 16375918 ]
Source organism: Mus musculus
Assembly composition: protein only structure
Assembly name:
Glucose-6-phosphate isomerase
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-139199 (Preferred)
search this ID

Entries 1 to 10 of 41