Entry status  (1)

REL

(62)

Experimental methods  (1)

X-ray diffraction

(62)

Authors  (109)

Kornberg RD

(29)

Bushnell DA

(28)

Westover KD

(23)

Cramer P

(18)

Wang D

(16)

Vassylyev DG

(10)

Vassylyeva MN

(10)

Brueckner F

(9)

Kaplan CD

(9)

Artsimovitch I

(8)

Huang X

(8)

Levitt M

(8)

RIKEN Structural Genomics/Proteomics Initiative (RSGI)

(7)

Perederina A

(6)

Carell T

(5)

Igarashi N

(5)

Matsugaki N

(5)

Tahirov TH

(5)

Wakatsuki S

(5)

Campbell EA

(4)

Darst SA

(4)

Ebright RH

(4)

Hennecke U

(4)

Severinov K

(4)

Svetlov V

(4)

Armache K-J

(3)

Armache KJ

(3)

Arnold E

(3)

Borukhov S

(3)

Hudson B

(3)

Irschik H

(3)

Ismail S

(3)

Jansen R

(3)

Kettenberger H

(3)

Laptenko O

(3)

Lee J

(3)

Mukhopadhyay J

(3)

Svetlov D

(3)

Tuske S

(3)

Zenkin N

(3)

Birktoft JJ

(2)

Clark AD

(2)

Dharia C

(2)

Fu J

(2)

Landick R

(2)

Lehmann E

(2)

Leon F

(2)

Leroy O

(2)

Napoli A

(2)

Palangat M

(2)

Pavlova O

(2)

Sarafianos SG

(2)

Sekine S

(2)

Sineva E

(2)

Wang X

(2)

Yokoyama S

(2)

Zhang J

(2)

Alt A

(1)

Bhagat S

(1)

Brunning A

(1)

Calero G

(1)

Cheung AC

(1)

Clark Jr AD

(1)

Damsma GE

(1)

Das K

(1)

Dengl S

(1)

Eisenfuehr A

(1)

Eisenführ A

(1)

Engel C

(1)

Famulok M

(1)

Gnatt AL

(1)

Goldfarb A

(1)

Hirata A

(1)

Hosaka T

(1)

Imanaka T

(1)

Jang M

(1)

Jun S-H

(1)

Jun SH

(1)

Kanai T

(1)

Kashkina E

(1)

Koppstein D

(1)

Korzheva N

(1)

Kostrewa D

(1)

Larsson K-M

(1)

Larsson KM

(1)

Meinhart A

(1)

Meyer PA

(1)

Minakhin L

(1)

Mitterweger S

(1)

Murakami K

(1)

Murakami KS

(1)

Mustaev A

(1)

Nair S

(1)

Nikiforov V

(1)

Ochi K

(1)

Patel J

(1)

Patlan V

(1)

Sainsbury S

(1)

Santangelo TJ

(1)

Sarafianos S

(1)

 

More...

Homo / hetero assembly  (1)

hetero

(62)

Assembly composition  (4)

protein/protein complex

(30)

DNA/RNA/protein complex

(28)

RNA/protein complex

(3)

DNA/DNA/RNA hybrid/protein complex

(1)

Assembly polymer count  (10)

tridecamer

(17)

hexamer

(12)

decamer

(8)

pentadecamer

(7)

dodecamer

(6)

octamer

(3)

tetradecamer

(3)

undecamer

(3)

pentamer

(2)

hexadecamer

(1)

Resolution distribution

2.0 - 2.5

(6)

2.5 - 3

(13)

3.0 - 3.5

(20)

3.5 - 4

(23)

Release year distribution

2000 - 2005

(28)

2005 - 2010

(43)

2010 - 2015

(2)

Journal  (9)

Cell

(22)

Science

(16)

Nature

(7)

Mol Cell

(4)

Nat Struct Mol Biol

(4)

J Biol Chem

(3)

Proc Natl Acad Sci U S A

(3)

EMBO J

(2)

Nat Commun

(1)

Organism superkingdom  (3)

Eukaryota

(44)

Bacteria

(17)

Archaea

(1)

Organism name  (7)

Saccharomyces cerevisiae

(42)

Thermus thermophilus

(8)

Thermus thermophilus HB8

(5)

Thermus aquaticus

(4)

Saccharomyces cerevisiae S288C

(1)

Schizosaccharomyces pombe 972h-

(1)

Thermococcus kodakarensis KOD1

(1)

Molecule name  (17)

DNA-directed RNA polymerase III largest subunit

(43)

RNA polymerase II subunit 1

(43)

RNA polymerase II subunit B1

(43)

DNA-directed RNA polymerase II subunit RPB1

(42)

RNA polymerase II subunit B220

(42)

DNA-directed RNA polymerase subunit beta'

(17)

RNA polymerase subunit beta'

(17)

RNAP subunit beta'

(17)

Transcriptase subunit beta'

(17)

A190

(1)

DNA-directed RNA polymerase I 190 kDa polypeptide

(1)

DNA-directed RNA polymerase I largest subunit

(1)

DNA-directed RNA polymerase I subunit RPA190

(1)

DNA-directed RNA polymerase II subunit rpb1

(1)

DNA-directed RNA polymerase subunit A'

(1)

DNA-directed RNA polymerase subunit Rpo1N

(1)

DNA-directed RNA polymerase, subunit A

(1)

Molecule type  (1)

Protein

(62)

Gene names  (18)

D2150

(42)

RPB1

(42)

RPB220

(42)

RPO21

(42)

SUA8

(42)

YDL140C

(42)

rpoC

(17)

TTHA1812

(13)

O6276

(1)

RPA1

(1)

RPA190

(1)

RRN1

(1)

SPBC28F2.12

(1)

TK1082

(1)

YOR341W

(1)

rpb1

(1)

rpo1N

(1)

rpoA1

(1)

Interacting Molecules  (91)

DNA-directed RNA polymerases I, II, and III subunit RPABC1

(44)

DNA-directed RNA polymerases I, II, and III subunit RPABC2

(44)

DNA-directed RNA polymerases I, II, and III subunit RPABC3

(44)

DNA-directed RNA polymerases I, II, and III subunit RPABC4

(44)

DNA-directed RNA polymerases I, II, and III subunit RPABC5

(44)

DNA-directed RNA polymerase II subunit RPB11

(43)

DNA-directed RNA polymerase II subunit RPB2

(43)

DNA-directed RNA polymerase II subunit RPB3

(43)

DNA-directed RNA polymerase II subunit RPB9

(43)

DNA-directed RNA polymerase subunit beta

(18)

DNA-directed RNA polymerase subunit alpha

(17)

DNA-directed RNA polymerase subunit omega

(17)

DNA-directed RNA polymerase II subunit RPB4

(14)

DNA-directed RNA polymerase II subunit RPB7

(14)

RNA polymerase sigma factor SigA

(10)

DNA (5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3')

(7)

DNA (28-MER)

(6)

28-MER DNA template strand

(5)

5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3'

(5)

5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*A)-3'

(5)

5'-D(*TP*AP*AP*GP*TP*AP*CP*TP*TP*GP *AP*GP*CP*T)-3'

(3)

5'-R(*UP*UP*CP*GP*AP*CP*CP*AP*GP*GP*AP)-3'

(3)

Alpha-amanitin

(3)

5'-D(*AP*AP*CP*GP*CP*CP*AP*GP*AP*CP*AP*GP*GP*G)-3'

(2)

5'-D(P*CP*CP*CP*TP*GP*TP*CP*TP*GP*GP*CP*GP*TP*TP*CP*GP*CP*GP*CP*GP*CP*CP*G)-3'

(2)

5'-R(*AP*AP*GP*AP*CP*CP*AP*GP*GP*C)-3'

(2)

5'-R(P*GP*AP*GP*UP*CP*UP*GP*CP*GP*GP*CP*GP*CP*GP*CP*G)-3'

(2)

RNA (5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*AP*UP*GP*C)-3')

(2)

Transcription elongation factor S-II

(2)

27-MER DNA template strand

(1)

31-MER

(1)

5'-D(*AP*AP*AP*CP*TP*AP*CP*TP*TP*GP *AP*GP*CP*T)-3'

(1)

5'-D(*AP*AP*GP*TP*AP*CP*T)-3'

(1)

5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP *CP*TP*TP*TP*TP*TTP*CP*BRUP*GP*GP*TP*CP*AP*TP*T)-3'

(1)

5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP *CP*TP*TP*TP*TTP*CP*CP*BRUP*GP*GP*TP*CP*AP*TP*T)-3'

(1)

5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP *CP*TP*TP*TTP*TP*CP*CP*BRUP*GP*GP*TP*CP*AP*TP*T)-3'

(1)

5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP *CP*TP*TTP*TP*TP*CP*CP*BRUP*GP*GP*TP*CP*AP*TP*T)-3'

(1)

5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP *GP*TP*TP*AP*CP*GP*CP*CP*BRUP*GP*GP*TP*CP*AP*TP*T)-3'

(1)

5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP*GP*CP*TP*GP*CP*TP*TP*TP*AP*TP*TP*GP*CP*AP*TP*T)-3'

(1)

5'-D(*CP*AP*AP*GP*TP*AP*G)-3'

(1)

5'-D(*CP*AP*GP*CP*TP*AP*CP*TP*TP*GP*AP*GP*CP*T)-3'

(1)

5'-D(*GP*TP*AP*CP*TP*TP*G)-3'

(1)

5'-D(*TP*AP*CP*TP*TP*GUP*CP*CP*CP*TP*CP*CP*TP*CP*AP*T)-3'

(1)

5'-D(P*AP*AP*AP*TP*GP*CP*CP*TP*GP*GP*TP*CP*T)-3'

(1)

5'-D(P*AP*GP*TP*AP*CP*TP*TP*AP*CP*GP*CP*CP*TP*GP*GP*TP*CP*AP*T)-3'

(1)

5'-D(P*CP*AP*AP*GP*TP*AP*CP*TP*TP*AP*CP*GP*CP*CP*TP*GP*GP*TP*CP*TP*T)-3'

(1)

5'-D(P*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*A)-3'

(1)

5'-R(*AP*AP*AP*GP*AP*CP*CP*AP*GP*GP*C)-3'

(1)

5'-R(*UP*GP*CP*AP*UP*UP*UP*CP*GP*CP*AP*AP*UP*AP*AP*A)-3'

(1)

5'-R(*UP*UP*CP*GP*AP*CP*CP*AP*GP*AP*UP)-3'

(1)

5'-R(*UP*UP*UP*GP*AP*GP*GP*AP*GP*G)-3'

(1)

5'-R(P*AP*UP*CP*GP*AP*GP*AP*GP*G)-3'

(1)

5'-R(P*GP*AP*CP*CP*AP*GP*GP*CP*A)-3'

(1)

DNA (29-MER)

(1)

DNA (5'-D(*AP*AP*CP*GP*CP*CP*AP*GP*AP*CP*AP*GP*GP*G)-3')

(1)

DNA (5'-D(*CP*TP*AP*CP*CP*CP*AP*TP*AP*AP*CP*CP*AP*CP*AP*GP*GP*CP*TP*CP*CP*TP*CP*TP*CP*CP*AP*TP*C)-3')

(1)

DNA (5'-D(P*CP*CP*CP*TP*GP*TP*CP*TP*GP*GP*CP*GP*TP*TP*CP*GP*CP*GP*CP*GP*CP*CP*G)-3')

(1)

DNA STRAND

(1)

DNA nontemplate strand

(1)

DNA template strand

(1)

DNA-directed RNA polymerase I subunit RPA12

(1)

DNA-directed RNA polymerase I subunit RPA135

(1)

DNA-directed RNA polymerase I subunit RPA14

(1)

DNA-directed RNA polymerase I subunit RPA34

(1)

DNA-directed RNA polymerase I subunit RPA43

(1)

DNA-directed RNA polymerase I subunit RPA49

(1)

DNA-directed RNA polymerase II subunit rpb4

(1)

DNA-directed RNA polymerase II subunit rpb7

(1)

DNA-directed RNA polymerase subunit Rpo10

(1)

DNA-directed RNA polymerase subunit Rpo11

(1)

DNA-directed RNA polymerase subunit Rpo12

(1)

DNA-directed RNA polymerase subunit Rpo1C

(1)

DNA-directed RNA polymerase subunit Rpo3

(1)

DNA-directed RNA polymerase subunit Rpo4

(1)

DNA-directed RNA polymerase subunit Rpo5

(1)

DNA-directed RNA polymerase subunit Rpo6

(1)

DNA-directed RNA polymerase subunit Rpo7

(1)

DNA-directed RNA polymerases I and III subunit RPAC1

(1)

DNA-directed RNA polymerases I and III subunit RPAC2

(1)

DNA/RNA (5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*AP*UP*GP*C)-D(P*AP*GP*AP*CP*G)-3')

(1)

RNA (5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*AP*UP*G)-3')

(1)

RNA (5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*AP*UP*GP*CP*AP*C)-3')

(1)

RNA (5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*AP*UP*GP*CP*AP*GP*AP*CP*GP*UP*UP*UP*UP*UP*U)-3')

(1)

RNA (5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*AP*UP*UP*C)-3')

(1)

RNA (5'-R(*CP*UP*UP*GP*AP*CP*GP*CP*CP*UP*GP*GP*UP*CP*AP*AP*A)-3')

(1)

RNA (5'-R(*UP*GP*AP*UP*UP*CP*UP*CP*UP*AP*UP*CP*GP*GP*AP*AP*UP*C)-3')

(1)

RNA (5'-R(*UP*GP*CP*AP*UP*AP*AP*AP*GP*AP*CP*CP*AP*GP*GP*C)-3')

(1)

RNA (5'-R(P*AP*UP*CP*GP*AP*GP*AP*GP*GP*AP*GP*C)-3')

(1)

RNA (5'-R(P*GP*AP*GP*UP*CP*UP*GP*CP*GP*GP*CP*GP*CP*GP*CP*G)-3')

(1)

RNA STRAND

(1)

RNA strand

(1)

Interacting ligands  (17)

ZN : ZINC ION

(59)

MG : MAGNESIUM ION

(45)

MN : MANGANESE (II) ION

(8)

ATP : ADENOSINE-5'-TRIPHOSPHATE

(3)

STD : STREPTOLYDIGIN

(3)

APC : DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER

(2)

DUT : DEOXYURIDINE-5'-TRIPHOSPHATE

(2)

G2P : PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER

(2)

GTP : GUANOSINE-5'-TRIPHOSPHATE

(2)

CTP : CYTIDINE-5'-TRIPHOSPHATE

(1)

DGT : 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE

(1)

G4P : GUANOSINE-5',3'-TETRAPHOSPHATE

(1)

MPD : (4S)-2-METHYL-2,4-PENTANEDIOL

(1)

NE6 : methyl [(1E,5R)-5-{(3S)-3-[(2E,4E)-2,5-dimethylocta-2,4-dienoyl]-2,4-dioxo-3,4-dihydro-2H-pyran-6-yl}hexylidene]carbamate

(1)

PB : LEAD (II) ION

(1)

PO4 : PHOSPHATE ION

(1)

TGT : TAGETITOXIN

(1)

EC number / name  (1)

2.7.7.6 : DNA-directed RNA polymerase

(62)

Biological function  (18)

DNA binding

(62)

DNA-directed RNA polymerase activity

(62)

5'-3' RNA polymerase activity

(60)

metal ion binding

(60)

nucleotidyltransferase activity

(60)

obsolete RNA polymerase I activity

(60)

obsolete RNA polymerase II activity

(60)

obsolete RNA polymerase III activity

(60)

obsolete RNA polymerase IV activity

(60)

obsolete RNA polymerase V activity

(60)

obsolete plastid single subunit type RNA polymerase activity

(60)

zinc ion binding

(59)

protein binding

(57)

obsolete mitochondrial single subunit type RNA polymerase activity

(44)

RNA-directed RNA polymerase activity

(42)

magnesium ion binding

(16)

chromatin-protein adaptor activity

(1)

promoter-specific chromatin binding

(1)

Biological process  (22)

DNA-templated transcription

(62)

plastid transcription

(60)

transcription by RNA polymerase I

(60)

transcription by RNA polymerase II

(60)

transcription by RNA polymerase III

(60)

transcription by RNA polymerase IV

(60)

transcription by RNA polymerase V

(60)

mitochondrial transcription

(44)

transcription elongation by RNA polymerase II

(43)

transcription initiation at RNA polymerase II promoter

(43)

RNA-templated transcription

(42)

translesion synthesis

(42)

7-methylguanosine mRNA capping

(1)

chromatin organization

(1)

co-transcriptional lncRNA 3' end processing, cleavage and polyadenylation pathway

(1)

intracellular phosphate ion homeostasis

(1)

nucleolar large rRNA transcription by RNA polymerase I

(1)

ribosome biogenesis

(1)

termination of RNA polymerase I transcription

(1)

termination of RNA polymerase II transcription

(1)

transcription elongation by RNA polymerase I

(1)

transcription initiation at RNA polymerase I promoter

(1)

Biological cell component  (10)

DNA-directed RNA polymerase complex

(60)

mitochondrion

(44)

nucleus

(44)

RNA polymerase II, core complex

(43)

cytoplasmic stress granule

(42)

RNA polymerase I complex

(1)

RNA polymerase II, holoenzyme

(1)

chromatin

(1)

cytoplasm

(1)

nucleolus

(1)

SCOP fold  (2)

beta and beta-prime subunits of DNA dependent RNA-polymerase

(38)

RNA polymerase

(11)

SCOP family  (2)

RNA-polymerase beta-prime

(38)

RNA polymerase

(11)

CATH class  (5)

Mainly Alpha

(62)

Mainly Beta

(60)

Alpha Beta

(56)

Few Secondary Structures

(5)

Special

(1)

CATH topology  (15)

Enzyme I; Chain A, domain 2

(62)

Topoisomerase I; Chain A, domain 4

(62)

Barwin-like endoglucanases

(60)

Dna Ligase; domain 1

(45)

Gyrase A; domain 2

(43)

OB fold (Dihydrolipoamide Acetyltransferase, E2P)

(15)

Wheat Germ Agglutinin (Isolectin 2); domain 1

(9)

Molybdopterin biosynthesis moea protein, domain 2

(6)

DNA Excision Repair, Uvrb; Chain A

(5)

Ribonucleotide Reductase Protein R1; domain 1

(4)

DNA polymerase; domain 1

(2)

PTS-regulatory domain, PRD

(2)

Alpha-Beta Plaits

(1)

Single alpha-helices involved in coiled-coils or other helix-helix interfaces

(1)

Tetracycline Repressor; domain 2

(1)

Pfam accession / name  (9)

PF00623 : RNA_pol_Rpb1_2

(62)

PF04983 : RNA_pol_Rpb1_3

(62)

PF04997 : RNA_pol_Rpb1_1

(62)

PF04998 : RNA_pol_Rpb1_5

(62)

PF05000 : RNA_pol_Rpb1_4

(62)

PF04990 : RNA_pol_Rpb1_7

(43)

PF04992 : RNA_pol_Rpb1_6

(43)

PF05001 : RNA_pol_Rpb1_R

(43)

PF21668 : RPOC_hybrid

(15)

Diffraction protocol  (2)

Single wavelength

(60)

MAD

(1)

Diffraction radiation source type  (1)

Synchrotron

(61)

Diffraction source  (13)

SSRL BEAMLINE BL11-1

(19)

SLS BEAMLINE X06SA

(13)

ALS BEAMLINE 5.0.2

(5)

NSLS BEAMLINE X25

(5)

PHOTON FACTORY BEAMLINE BL-5A

(5)

SSRL BEAMLINE BL9-2

(5)

APS BEAMLINE 22-ID

(3)

APS BEAMLINE 19-ID

(2)

SPRING-8 BEAMLINE BL45PX

(2)

ALS BEAMLINE 8.2.2

(1)

CHESS BEAMLINE A1

(1)

CHESS BEAMLINE F1

(1)

SLS BEAMLINE X10SA

(1)

Synchrotron site  (8)

SSRL

(24)

SLS

(13)

ALS

(5)

APS

(5)

NSLS

(5)

Photon Factory

(5)

CHESS

(2)

SPring-8

(2)

Diffraction detector type  (3)

CCD

(51)

Image plate

(2)

Pixel

(2)

Refinement software  (3)

CNS

(39)

REFMAC

(19)

PHENIX

(4)

Representative Structures

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95%

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70%

50%

40%

30%