Entry status  (1)

REL

(146)

Experimental methods  (2)

X-ray diffraction

(133)

Electron Microscopy

(13)

Authors  (249)

Cramer P

(48)

Kornberg RD

(42)

Bushnell DA

(41)

Wang D

(23)

Westover KD

(23)

Huang X

(22)

Cheung AC

(21)

Cheung ACM

(20)

Brueckner F

(15)

Sainsbury S

(15)

Kaplan CD

(13)

Liu X

(13)

Silva DA

(12)

Vassylyev DG

(11)

Vassylyeva MN

(11)

Darst SA

(10)

Muller CW

(10)

Müller CW

(10)

Artsimovitch I

(9)

Damsma GE

(9)

Campbell EA

(8)

Ebright RH

(8)

Lehmann E

(8)

Levitt M

(8)

Arnold E

(7)

Dengl S

(7)

RIKEN Structural Genomics/Proteomics Initiative (RSGI)

(7)

Sadian Y

(7)

Tafur L

(7)

Wetzel R

(7)

Calero G

(6)

Carell T

(6)

Perederina A

(6)

Sydow JF

(6)

Tuske S

(6)

Vassylyev D

(6)

Igarashi N

(5)

Matsugaki N

(5)

Spahr H

(5)

Tahirov TH

(5)

Wakatsuki S

(5)

Abrescia NG

(4)

Abrescia NGA

(4)

Bae B

(4)

Barnes CO

(4)

Bell SD

(4)

Brown D

(4)

Brown IS

(4)

Calero M

(4)

Cohen AE

(4)

Davis E

(4)

Engel C

(4)

Feng Y

(4)

Fernandez-Tornero C

(4)

Fernández-Tornero C

(4)

Graham BW

(4)

Hanske J

(4)

Hennecke U

(4)

Landick R

(4)

Lin G

(4)

Malik I

(4)

Moreno-Morcillo M

(4)

Pullara F

(4)

Severinov K

(4)

Svetlov V

(4)

Trakselis MA

(4)

Weis F

(4)

Wigneshweraraj S

(4)

Zhang Q

(4)

Zhang Y

(4)

Armache K-J

(3)

Armache KJ

(3)

Borukhov S

(3)

Chatterjee S

(3)

Chong J

(3)

Gruene T

(3)

Hagen WJ

(3)

Hagen WJH

(3)

Hirata A

(3)

Ho MX

(3)

Hoffmann NA

(3)

Hudson B

(3)

Irschik H

(3)

Ismail S

(3)

Jakobi AJ

(3)

Jansen R

(3)

Kettenberger H

(3)

Kinkelin K

(3)

Laptenko O

(3)

Lee J

(3)

Legrand P

(3)

Lidschreiber M

(3)

Mukhopadhyay J

(3)

Murakami KS

(3)

Neyer S

(3)

Rashid UJ

(3)

Rothbart SB

(3)

Ruiz FM

(3)

Sachse C

(3)

Steuerwald U

(3)

 

More...

Homo / hetero assembly  (2)

hetero

(144)

homo

(2)

Assembly composition  (6)

DNA/RNA/protein complex

(86)

protein/protein complex

(50)

DNA/protein complex

(4)

RNA/protein complex

(3)

protein structure

(2)

DNA/DNA/RNA hybrid/protein complex

(1)

Assembly polymer count  (17)

pentadecamer

(32)

tridecamer

(28)

dodecamer

(20)

hexamer

(15)

decamer

(8)

tetradecamer

(8)

hexadecamer

(7)

octamer

(6)

heptadecamer

(5)

undecamer

(5)

heptamer

(3)

dimer

(2)

icosamer

(2)

pentamer

(2)

21-mer

(1)

monomer

(1)

nonamer

(1)

Resolution distribution

1.5 - 2

(1)

2.0 - 2.5

(8)

2.5 - 3

(19)

3.0 - 3.5

(61)

3.5 - 4

(57)

Release year distribution

2000 - 2005

(28)

2005 - 2010

(60)

2010 - 2015

(59)

2015 - 2020

(20)

Journal  (14)

Science

(32)

Cell

(24)

Nature

(21)

Mol Cell

(18)

Proc Natl Acad Sci U S A

(14)

EMBO J

(13)

Elife

(7)

J Biol Chem

(5)

Nat Struct Mol Biol

(4)

PLoS Biol

(3)

Structure

(2)

Biochem Soc Trans

(1)

Nat Commun

(1)

Nucleic Acids Res

(1)

Organism superkingdom  (3)

Eukaryota

(109)

Bacteria

(30)

Archaea

(7)

Organism name  (12)

Saccharomyces cerevisiae

(84)

Saccharomyces cerevisiae S288C

(24)

Thermus thermophilus

(9)

Thermus thermophilus HB8

(9)

Escherichia coli DH1

(4)

Saccharolobus shibatae

(4)

Thermus aquaticus

(4)

Escherichia coli K-12

(2)

Mycobacterium tuberculosis

(2)

Saccharolobus solfataricus P2

(2)

Schizosaccharomyces pombe 972h-

(1)

Thermococcus kodakarensis KOD1

(1)

Molecule name  (18)

DNA-directed RNA polymerase II subunit RPB2

(92)

RNA polymerase II subunit 2

(92)

B150

(91)

DNA-directed RNA polymerase II 140 kDa polypeptide

(91)

DNA-directed RNA polymerase subunit beta

(35)

RNA polymerase subunit beta

(26)

RNAP subunit beta

(26)

Transcriptase subunit beta

(26)

A135

(17)

DNA-directed RNA polymerase I 135 kDa polypeptide

(17)

DNA-directed RNA polymerase I polypeptide 2

(17)

DNA-directed RNA polymerase I subunit RPA135

(17)

RNA polymerase I subunit 2

(17)

DNA-directed RNA polymerase subunit Rpo2

(6)

DNA-directed RNA polymerase subunit B

(2)

DNA-directed RNA polymerase II 138 kDa polypeptide

(1)

DNA-directed RNA polymerase, subunit B

(1)

RNA polymerase II subunit B2

(1)

Molecule type  (1)

Protein

(146)

Gene names  (32)

RPB150

(91)

RPB2

(91)

RPO22

(91)

YOR151C

(91)

rpoB

(26)

TTHA1813

(18)

RPA135

(17)

RPA2

(17)

RRN2

(17)

SRP3

(17)

YP9531.03C

(17)

YPR010C

(17)

rpo2

(6)

J5U23_00030

(4)

JW3950

(2)

MTCI376.08c

(2)

Rv0667

(2)

SSO0227/SSO3254

(2)

b3987

(2)

groN

(2)

nitB

(2)

rif

(2)

ron

(2)

rpoB1

(2)

rpoB2

(2)

stl

(2)

stv

(2)

tabD

(2)

SPAC23G3.01

(1)

SPAC521.06

(1)

TK1083

(1)

rpb2

(1)

Interacting Molecules  (210)

DNA-directed RNA polymerases I, II, and III subunit RPABC1

(109)

DNA-directed RNA polymerases I, II, and III subunit RPABC2

(109)

DNA-directed RNA polymerases I, II, and III subunit RPABC3

(109)

DNA-directed RNA polymerases I, II, and III subunit RPABC4

(109)

DNA-directed RNA polymerases I, II, and III subunit RPABC5

(109)

DNA-directed RNA polymerase II subunit RPB11

(92)

DNA-directed RNA polymerase II subunit RPB3

(92)

DNA-directed RNA polymerase II subunit RPB9

(92)

DNA-directed RNA polymerase II subunit RPB1

(91)

DNA-directed RNA polymerase II subunit RPB4

(44)

DNA-directed RNA polymerase II subunit RPB7

(44)

DNA-directed RNA polymerase subunit alpha

(27)

DNA-directed RNA polymerase subunit beta'

(27)

DNA-directed RNA polymerase subunit omega

(27)

DNA-directed RNA polymerase I subunit RPA12

(17)

DNA-directed RNA polymerase I subunit RPA14

(17)

DNA-directed RNA polymerase I subunit RPA190

(17)

DNA-directed RNA polymerase I subunit RPA43

(17)

DNA-directed RNA polymerases I and III subunit RPAC1

(17)

DNA-directed RNA polymerases I and III subunit RPAC2

(17)

DNA-directed RNA polymerase I subunit RPA34

(14)

DNA-directed RNA polymerase I subunit RPA49

(14)

RNA polymerase sigma factor SigA

(14)

DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*CP*TP*CP*TP*CP*GP*AP*TP*G)-3')

(9)

DNA (5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3')

(9)

RNA

(9)

DNA (28-MER)

(8)

DNA-directed RNA polymerase subunit Rpo10

(7)

DNA-directed RNA polymerase subunit Rpo11

(7)

DNA-directed RNA polymerase subunit Rpo12

(7)

DNA-directed RNA polymerase subunit Rpo1C

(7)

DNA-directed RNA polymerase subunit Rpo1N

(7)

DNA-directed RNA polymerase subunit Rpo3

(7)

DNA-directed RNA polymerase subunit Rpo4

(7)

DNA-directed RNA polymerase subunit Rpo5

(7)

DNA-directed RNA polymerase subunit Rpo6

(7)

DNA-directed RNA polymerase subunit Rpo7

(7)

28-MER DNA template strand

(5)

5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3'

(5)

5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*A)-3'

(5)

5'-R(*UP*UP*CP*GP*AP*CP*CP*AP*GP*GP*AP)-3'

(5)

DNA-directed RNA polymerase subunit Rpo13

(5)

DNA-directed RNA polymerase subunit Rpo8

(5)

RNA polymerase sigma factor RpoD

(5)

Non-template strand

(4)

Template strand

(4)

5'-D(*AP*CP*TP*AP*CP*TP*TP*GP*AP*GP*CP*T)-3'

(3)

5'-D(*TP*AP*AP*GP*TP*AP*CP*TP*TP*GP *AP*GP*CP*T)-3'

(3)

5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G)-3'

(3)

Alpha-amanitin

(3)

DNA (29-MER)

(3)

DNA template strand

(3)

Non-template DNA

(3)

RNA polymerase I-specific transcription initiation factor RRN11

(3)

RNA polymerase I-specific transcription initiation factor RRN6

(3)

RNA polymerase I-specific transcription initiation factor RRN7

(3)

Template DNA

(3)

Transcription elongation factor S-II

(3)

Transcription factor BYE1

(3)

Transcription initiation factor IIB

(3)

non-template DNA

(3)

template DNA

(3)

5'-D(*AP*AP*CP*GP*CP*CP*AP*GP*AP*CP*AP*GP*GP*G)-3'

(2)

5'-D(*AP*AP*GP*TP*AP*CP*TP)-3'

(2)

5'-D(P*CP*CP*CP*TP*GP*TP*CP*TP*GP*GP*CP*GP*TP*TP*CP*GP*CP*GP*CP*GP*CP*CP*G)-3'

(2)

5'-R(*AP*AP*GP*AP*CP*CP*AP*GP*GP*C)-3'

(2)

5'-R(*AP*CP*CP*AP*GP*GP*AP)-3'

(2)

5'-R(*UP*GP*CP*AP*UP*UP*U*CP*AP*AP*CP*CP*AP*GP*GP*CP*UP*U)-3'

(2)

5'-R(P*GP*AP*GP*UP*CP*UP*GP*CP*GP*GP*CP*GP*CP*GP*CP*G)-3'

(2)

Bacterial RNA polymerase inhibitor

(2)

DNA (5'-D(*AP*G*CP*TP*CP*AP*AP*GP*TP*AP*CP*TP*TP*AP*(8OG)P*GP*CP*CP*(BRU)P*GP*GP*TP*CP*AP*TP*T)-3')

(2)

DNA (5'-D(*AP*GP*TP*AP*CP*TP*TP*GP*AP*GP*CP*T)-3')

(2)

DNA non-template strand

(2)

NON TEMPLATE DNA 5'-D(*TP*AP*AP*GP*TP*AP*CP*TP*TP*GP*AP *GP*CP*TP)-3'

(2)

NON-TEMPLATE STRAND DNA (38-MER)

(2)

RNA (5'-D(*AP*UP*GP*GP*AP*GP*AP*GP*G)-3')

(2)

RNA (5'-R(*AP*GP*AP*GP*G)-3')

(2)

RNA (5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*AP*UP*GP*C)-3')

(2)

RNA (5'-R(P*UP*CP*GP*AP*GP*AP*GP*GP*A)-3')

(2)

RNA product strand

(2)

Synthetic DNA

(2)

Synthetic RNA

(2)

TEMPLATE DNA

(2)

TRANSCRIPT RNA 5'-R(*CP*CP*AP*GP*GP*AP)-3'

(2)

non-template strand DNA

(2)

template strand DNA

(2)

, 5'-D(*DAP*AP*AP*GP*TP*AP*CP*TP*TP*GP*AP*GP*CP*DTP)-3'

(1)

27-MER DNA template strand

(1)

31-MER

(1)

5'-D(*A*AP*CP*TP*AP*CP*TP*TP*GP*AP*GP*CP*T)-3'

(1)

5'-D(*AP*AP*AP*CP*TP*AP*CP*TP*TP*GP *AP*GP*CP*T)-3'

(1)

5'-D(*AP*AP*AP*GP*TP*AP*CP*TP*TP*GP*AP*GP*CP*TP)-3'

(1)

5'-D(*AP*AP*GP*TP*AP*CP*T)-3'

(1)

5'-D(*AP*GP*CP*GP*CP*AP*GP*TP*TP*GP*TP*GP*CP*TP *AP*TP*GP*AP*TP*AP*TP*TP*TP*TP*TP*AP*TP)-3'

(1)

5'-D(*AP*GP*CP*TP*AP*GP*CP*TP*TP*AP*CP*CP*TP*GP *GP*TP*GP* BRUP*TP*GP*CP*TP*CP*TP*AP*AP*DC)-3'

(1)

5'-D(*AP*GP*CP*TP*AP*GP*CP*TP*TP*TP*CP*BRUP*AP*CP*CP *TP*GP*AP*AP*CP*AP*AP*CP*TP*AP*AP*CP)-3'

(1)

5'-D(*AP*GP*CP*TP*C*AP*AP*GP*TP*AP*GP*TP*TP*AP*AP*GP*CP*CP*(BRU)P*GP*GP*TP*CP*AP*TP*T)-3'

(1)

5'-D(*AP*GP*CP*TP*C*AP*AP*GP*TP*AP*GP*TP*TP*AP*TP*GP*CP*CP*(BRU)P*GP*GP*TP*CP*AP*TP*T)-3'

(1)

5'-D(*AP*GP*CP*TP*C*AP*AP*GP*TP*AP*GP*TP*TP*CP*TP*GP*CP*CP*(BRU)P*GP*GP*TP*CP*AP*TP*T)-3'

(1)

5'-D(*AP*GP*CP*TP*CP*A*AP*GP*TP*AP*GP*TP*TP*AP*TP*GP*CP*CP*(BRU)P*GP*GP*TP*CP*AP*TP*T)-3'

(1)

 

More...

Interacting ligands  (26)

ZN : ZINC ION

(113)

MG : MAGNESIUM ION

(14)

APC : DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER

(7)

G2P : PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER

(6)

MN : MANGANESE (II) ION

(6)

ATP : ADENOSINE-5'-TRIPHOSPHATE

(4)

SO4 : SULFATE ION

(4)

GTP : GUANOSINE-5'-TRIPHOSPHATE

(3)

STD : STREPTOLYDIGIN

(3)

DUT : DEOXYURIDINE-5'-TRIPHOSPHATE

(2)

RFP : RIFAMPICIN

(2)

UTP : URIDINE 5'-TRIPHOSPHATE

(2)

ACT : ACETATE ION

(1)

C7P : cis-diammine(pyridine)chloroplatinum(II)

(1)

CTP : CYTIDINE-5'-TRIPHOSPHATE

(1)

DGT : 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE

(1)

EPE : 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID

(1)

G4P : GUANOSINE-5',3'-TETRAPHOSPHATE

(1)

MPD : (4S)-2-METHYL-2,4-PENTANEDIOL

(1)

MXP : Myxopyronin B

(1)

NE6 : methyl [(1E,5R)-5-{(3S)-3-[(2E,4E)-2,5-dimethylocta-2,4-dienoyl]-2,4-dioxo-3,4-dihydro-2H-pyran-6-yl}hexylidene]carbamate

(1)

PO4 : PHOSPHATE ION

(1)

RBT : RIFABUTIN

(1)

RPT : RIFAPENTINE

(1)

SRN : SORANGICIN A

(1)

TGT : TAGETITOXIN

(1)

EC number / name  (1)

2.7.7.6 : DNA-directed RNA polymerase

(142)

Biological function  (18)

DNA binding

(146)

DNA-directed RNA polymerase activity

(146)

ribonucleoside binding

(145)

5'-3' RNA polymerase activity

(138)

nucleotidyltransferase activity

(138)

obsolete RNA polymerase I activity

(138)

obsolete RNA polymerase II activity

(138)

obsolete RNA polymerase III activity

(138)

obsolete RNA polymerase IV activity

(138)

obsolete RNA polymerase V activity

(138)

obsolete plastid single subunit type RNA polymerase activity

(138)

zinc ion binding

(115)

protein binding

(109)

obsolete mitochondrial single subunit type RNA polymerase activity

(108)

RNA-directed RNA polymerase activity

(90)

mRNA binding

(90)

metal ion binding

(7)

RNA binding

(1)

Biological process  (30)

DNA-templated transcription

(146)

plastid transcription

(138)

transcription by RNA polymerase I

(138)

transcription by RNA polymerase II

(138)

transcription by RNA polymerase III

(138)

transcription by RNA polymerase IV

(138)

transcription by RNA polymerase V

(138)

mitochondrial transcription

(108)

transcription initiation at RNA polymerase II promoter

(91)

RNA-templated transcription

(90)

transcription elongation by RNA polymerase II

(90)

nucleolar large rRNA transcription by RNA polymerase I

(17)

ribosome biogenesis

(17)

termination of RNA polymerase I transcription

(17)

transcription elongation by RNA polymerase I

(17)

transcription initiation at RNA polymerase I promoter

(17)

DNA-templated transcription initiation

(1)

bacterial-type flagellum assembly

(1)

bacterial-type flagellum-dependent cell motility

(1)

cell motility

(1)

cellular response to cell envelope stress

(1)

intracellular iron ion homeostasis

(1)

nitrate assimilation

(1)

regulation of DNA-templated transcription elongation

(1)

regulation of DNA-templated transcription initiation

(1)

response to antibiotic

(1)

response to heat

(1)

siRNA-mediated pericentric heterochromatin formation

(1)

submerged biofilm formation

(1)

transcription antitermination

(1)

Biological cell component  (14)

DNA-directed RNA polymerase complex

(138)

mitochondrion

(108)

nucleus

(108)

RNA polymerase II, core complex

(91)

cytoplasmic stress granule

(90)

RNA polymerase I complex

(17)

nucleolus

(17)

cytoplasm

(8)

cytosol

(2)

RNA polymerase II, holoenzyme

(1)

cytosolic DNA-directed RNA polymerase complex

(1)

membrane

(1)

pericentric heterochromatin

(1)

transcription elongation factor complex

(1)

SCOP fold  (2)

beta and beta-prime subunits of DNA dependent RNA-polymerase

(43)

RNA polymerase

(6)

SCOP family  (2)

RNA-polymerase beta

(43)

RNA polymerase

(6)

CATH class  (3)

Alpha Beta

(146)

Mainly Beta

(143)

Special

(5)

CATH topology  (8)

Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; domain 3

(146)

Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; Domain 6

(143)

OB fold (Dihydrolipoamide Acetyltransferase, E2P)

(143)

DCoH-like

(116)

Hypothetical Protein Ta0175; Chain: A, domain 2

(116)

Rna Polymerase Beta Subunit; Chain: C, domain 4

(27)

Rna Polymerase Beta Subunit; Chain: C,domain 2

(24)

Helix Hairpins

(5)

Pfam accession / name  (9)

PF04561 : RNA_pol_Rpb2_2

(142)

PF04563 : RNA_pol_Rpb2_1

(142)

PF00562 : RNA_pol_Rpb2_6

(139)

PF04560 : RNA_pol_Rpb2_7

(139)

PF04565 : RNA_pol_Rpb2_3

(139)

PF04566 : RNA_pol_Rpb2_4

(99)

PF04567 : RNA_pol_Rpb2_5

(99)

PF10385 : RNA_pol_Rpb2_45

(23)

PF06883 : RNA_pol_Rpa2_4

(17)

Diffraction protocol  (2)

Single wavelength

(131)

MAD

(1)

Diffraction radiation source type  (2)

Synchrotron

(130)

Rotating anode

(2)

Diffraction source  (28)

SLS BEAMLINE X06SA

(38)

SSRL BEAMLINE BL11-1

(32)

NSLS BEAMLINE X25

(8)

ALS BEAMLINE 5.0.2

(7)

APS BEAMLINE 23-ID-D

(5)

PHOTON FACTORY BEAMLINE BL-5A

(5)

SSRL BEAMLINE BL9-2

(5)

NSLS BEAMLINE X29A

(4)

APS BEAMLINE 22-ID

(3)

CHESS BEAMLINE F1

(3)

APS BEAMLINE 19-ID

(2)

ESRF BEAMLINE ID29

(2)

RIGAKU RU200

(2)

SLS BEAMLINE X06DA

(2)

SOLEIL BEAMLINE PROXIMA 1

(2)

SPRING-8 BEAMLINE BL45PX

(2)

SSRL BEAMLINE BL12-2

(2)

ALS BEAMLINE 5.0.3

(1)

ALS BEAMLINE 8.2.1

(1)

ALS BEAMLINE 8.2.2

(1)

APS BEAMLINE 14-BM-C

(1)

APS BEAMLINE 23-ID-B

(1)

APS BEAMLINE 24-ID-C

(1)

CHESS BEAMLINE A1

(1)

ESRF BEAMLINE ID14-1

(1)

NSLS BEAMLINE X3A

(1)

PETRA III, EMBL c/o DESY BEAMLINE P14 (MX2)

(1)

SLS BEAMLINE X10SA

(1)

Synchrotron site  (11)

SLS

(40)

SSRL

(39)

APS

(13)

NSLS

(13)

ALS

(9)

Photon Factory

(5)

CHESS

(4)

ESRF

(3)

SOLEIL

(2)

SPring-8

(2)

PETRA III, EMBL c/o DESY

(1)

Diffraction detector type  (3)

CCD

(85)

Pixel

(34)

Image plate

(5)

Refinement software  (5)

CNS

(50)

BUSTER

(34)

REFMAC

(30)

PHENIX

(29)

BUSTER-TNT

(13)

EM microscope model  (1)

FEI TITAN KRIOS

(13)

EM detector name  (3)

GATAN K2 SUMMIT (4k x 4k)

(10)

GATAN K2 QUANTUM (4k x 4k)

(2)

FEI FALCON II (4k x 4k)

(1)

Representative Structures

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