All structure family : Single Heli x bin
 
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revised
(1)
 
Entry Information
Entry status  (1)
REL
(63)
 
Experimental methods  (1)
X-ray diffraction
(63)
 
Authors  (37)
Steitz TA
(60)
Moore PB
(46)
Blaha G
(28)
Schmeing TM
(21)
Gurel G
(18)
Gürel G
(18)
Schroeder SJ
(16)
Hansen JL
(14)
Strobel SA
(13)
Huang KS
(12)
Kitchen DE
(9)
Ban N
(7)
Tu D
(7)
Nissen P
(6)
Ippolito JA
(5)
Hansen J
(4)
Kanyo ZF
(2)
Simonovic M
(2)
Simonović M
(2)
Tirado-Rives J
(2)
Bukau B
(1)
Deuerling E
(1)
Duffy EM
(1)
Ferbitz L
(1)
Franceschi FJ
(1)
Freeborn B
(1)
Kanyo ZK
(1)
Kavran JM
(1)
Klein DJ
(1)
Maier T
(1)
Patzelt H
(1)
Scaringe SA
(1)
Seila AC
(1)
Soukup JK
(1)
Steitz T
(1)
TU D
(1)
Wang D
(1)
 
Homo / hetero assembly  (1)
hetero
(63)
 
Assembly composition  (2)
RNA/protein complex
(61)
DNA/RNA hybrid/RNA/protein complex
(2)
 
Assembly polymer count  (4)
31-mer
(33)
32-mer
(16)
30-mer
(9)
33-mer
(5)
 
Resolution distribution
2.0 - 2.5
(12)
2.5 - 3
(41)
3.0 - 3.5
(10)
 
Release year distribution
2000 - 2005
(37)
2005 - 2010
(44)
2010 - 2015
(3)
 
Journal  (9)
J Mol Biol
(24)
Mol Cell
(13)
Cell
(7)
Proc Natl Acad Sci U S A
(5)
Nature
(4)
RNA
(4)
Antimicrob Agents Chemother
(3)
J Med Chem
(1)
Nat Struct Biol
(1)
 
Macromolecules
Organism superkingdom  (1)
Archaea
(63)
 
Organism name  (1)
Haloarcula marismortui
(63)
 
Molecule name  (4)
50S ribosomal protein L19e
(63)
Hl24
(63)
Hmal19
(63)
Large ribosomal subunit protein eL19
(63)
 
Molecule type  (1)
Protein
(63)
 
Gene names  (2)
rpl19e
(63)
rrnAC1594
(63)
 
Interacting Molecules  (60)
5S ribosomal RNA
(63)
Large ribosomal subunit protein eL15
(63)
Large ribosomal subunit protein eL18
(63)
Large ribosomal subunit protein eL21
(63)
Large ribosomal subunit protein eL24
(63)
Large ribosomal subunit protein eL31
(63)
Large ribosomal subunit protein eL32
(63)
Large ribosomal subunit protein eL37
(63)
Large ribosomal subunit protein eL39
(63)
Large ribosomal subunit protein eL42
(63)
Large ribosomal subunit protein eL43
(63)
Large ribosomal subunit protein eL8
(63)
Large ribosomal subunit protein uL10
(63)
Large ribosomal subunit protein uL13
(63)
Large ribosomal subunit protein uL14
(63)
Large ribosomal subunit protein uL15
(63)
Large ribosomal subunit protein uL18
(63)
Large ribosomal subunit protein uL2
(63)
Large ribosomal subunit protein uL22
(63)
Large ribosomal subunit protein uL23
(63)
Large ribosomal subunit protein uL24
(63)
Large ribosomal subunit protein uL29
(63)
Large ribosomal subunit protein uL3
(63)
Large ribosomal subunit protein uL30
(63)
Large ribosomal subunit protein uL4
(63)
Large ribosomal subunit protein uL5
(63)
Large ribosomal subunit protein uL6
(63)
23S ribosomal RNA
(62)
Large ribosomal subunit protein uL16
(62)
Large ribosomal subunit protein uL11
(44)
5'-R(*CP*CP*(DA)*(PHE)*(ACA))-3'
(2)
5'-R(*CP*CP*AP*(PHE)*(ACA))-3'
(2)
5'-R(*CP*CP*AP*(PHE)*(ACA)*(BTN))-3'
(2)
CCA
(2)
RNA (5'-R(*CP*CP*(8AN))-3')
(2)
5'-D(*(DC)P*(DC)P*(5AA)P*(2OP)P*(PO2)P*AP*C*C)-3')
(1)
5'-R(*(DC)P*(DC)P*(PPU)*(LOF)P*(PO2)P*AP*C*C)-3'
(1)
5'-R(*CP*(5AA)*(HFA))-3'
(1)
5'-R(*CP*CP*(5AA)P*(2OP)P*(PAE)P*AP*C*C)-3')
(1)
5'-R(*CP*CP*(5AA)P*(2OP)P*(PO2)P*(DA)P*C*C)-3')
(1)
5'-R(*CP*CP*(PPU))-3'
(1)
5'-R(*CP*CP*(PPU)*(LOF))-3'
(1)
5'-R(*CP*CP*(PPU)*(TSE)*(DA)*CP*C)-3'
(1)
5'-R(*CP*CP*(PPU)P*(PO2)P*(DA)P*C*C)-3')
(1)
50S RIBOSOMAL RNA
(1)
50S ribosomal protein L10e
(1)
CC-Pmn-pcb
(1)
CC-puromycin
(1)
CCA-phenylalanine-cariotic-acid-biotin
(1)
CCdA-P-Puromycin
(1)
DNA/RNA (5'-R(*CP*CP*(5AA)P*(2OP)P*(PO2)P*AP*CP*C)-3')
(1)
Deacylated tRNA minihelix
(1)
Oligonucleotide CCA
(1)
QUINUPRISTIN
(1)
RNA (5'-R(*C*CP*A)-3')
(1)
RNA (5'-R(*CP*CP*(PPU))-3')
(1)
RNA (5'-R(*CP*CP*A)-3')
(1)
Trigger factor
(1)
VIRGINIAMYCIN S1
(1)
minihelix-puromycin
(1)
 
Function and Biology
Biological function  (4)
RNA binding
(63)
large ribosomal subunit rRNA binding
(63)
rRNA binding
(63)
structural constituent of ribosome
(63)
 
Biological process  (1)
translation
(63)
 
Biological cell component  (3)
cytosolic large ribosomal subunit
(63)
ribonucleoprotein complex
(63)
ribosome
(63)
 
Sequence and Structure classification
SCOP fold  (2)
Ribosomal protein L19 (L19e)
(56)
Ribosome and ribosomal fragments
(1)
 
SCOP family  (2)
Ribosomal protein L19 (L19e)
(56)
Large subunit
(1)
 
CATH class  (1)
Mainly Alpha
(63)
 
CATH topology  (3)
50s Ribosomal Protein L19e, Chain O, domain 1
(63)
Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A
(63)
Single alpha-helices involved in coiled-coils or other helix-helix interfaces
(63)
 
Pfam accession / name  (1)
PF01280 : Ribosomal_L19e
(63)
 
Experimental Information
Diffraction protocol  (1)
Single wavelength
(63)
 
Diffraction radiation source type  (1)
Synchrotron
(63)
 
Diffraction source  (7)
NSLS BEAMLINE X25
(23)
APS BEAMLINE 19-ID
(17)
NSLS BEAMLINE X29A
(16)
APS BEAMLINE 24-ID-C
(9)
ALS BEAMLINE 8.2.2
(2)
APS BEAMLINE 8-BM
(2)
ESRF BEAMLINE BM1A
(1)
 
Synchrotron site  (4)
NSLS
(39)
APS
(28)
ALS
(2)
ESRF
(1)
 
Diffraction detector type  (2)
CCD
(62)
Image plate
(2)
 
Refinement software  (3)
CNS
(62)
CNX
(2)
REFMAC
(1)
 
Representative Structures
Representative Structures
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Entries 1 to 10 of 63
Entries 1 to 10 of 63
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Co-crystal structure of Mycalamide A Bound to the Large Ribosomal Subunit
Gurel G, Blaha G, Steitz TA, Moore PB
Antimicrob Agents Chemother (2009) [PMID: 19738021  ]
Assembly composition: DNA/RNA hybrid/RNA/protein complex
Bound ligands: K    K    MG    SR    SR    NA    CD    CL    MG    MYL    CD    MYL    NA   
Modified residues: OMG    2OP    OMU    5AA    5AA    UR3    1MA    1MA    PSU    PSU    OMG    OMU    UR3   
Assembly name: Large ribosomal protein and RNA (Preferred)   search this complex
PDBe complex ID: PDB-CPX-113128 (Preferred)   search this ID
PDBe-KB: P14119    P29198    P14123    P10971    P32410    P12737    (view 23 more)
X-ray diffraction
3.11Å resolution
Released: 9 Mar 2010
Model geometry
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3i55
3i55
3i55
Co-crystal structure of Triacetyloleandomcyin Bound to the Large Ribosomal Subunit
Gurel G, Blaha G, Steitz TA, Moore PB
Antimicrob Agents Chemother (2009) [PMID: 19738021  ]
Assembly composition: RNA/protein complex
Bound ligands: K    K    MG    SR    SR    NA    CD    CL    MG    TAO    TAO    CD    NA   
Modified residues: OMG    OMU    UR3    1MA    1MA    PSU    PSU    OMG    OMU    UR3   
Assembly name: Large ribosomal protein and RNA (Preferred)   search this complex
PDBe complex ID: PDB-CPX-145591 (Preferred)   search this ID
PDBe-KB: P14119    P29198    P14123    P10971    P32410    P12737    (view 23 more)
X-ray diffraction
2.9Å resolution
Released: 9 Mar 2010
Model geometry
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3i56
3i56
3i56
Crystal Structure of Enhanced Macrolide Bound to 50S Ribosomal Subunit
Kanyo ZF
Assembly composition: RNA/protein complex
Bound ligands: K    K    MG    SR    SR    EMK    EMK    NA    CD    CL    MG    CD    NA   
PDBe complex ID: PDB-CPX-102793 (Preferred)   search this ID
PDBe-KB: P14119    P29198    A0A0X1KGB4    P14123    P10971    P32410    (view 22 more)
X-ray diffraction
2.7Å resolution
Released: 20 Jun 2012
Model geometry
Fit model/data
3ow2
3ow2
3ow2
Co-crystal structure of Homoharringtonine bound to the large ribosomal subunit
Gurel G, Blaha G, Moore PB, Steitz TA
J Mol Biol (2009) [PMID: 19362093  ]
Assembly composition: RNA/protein complex
Bound ligands: K    K    MG    HMT    SR    SR    NA    CD    CL    MG    CD    NA   
Modified residues: OMG    OMU    UR3    1MA    1MA    PSU    PSU    OMG    OMU    UR3   
Assembly name: Large ribosomal protein and RNA (Preferred)   search this complex
PDBe complex ID: PDB-CPX-145589 (Preferred)   search this ID
PDBe-KB: P14119    P29198    P14123    P10971    P32410    P12737    (view 23 more)
X-ray diffraction
2.7Å resolution
Released: 28 Apr 2009
Model geometry
Fit model/data
3g6e
3g6e
3g6e
Co-crystal structure of Bruceantin bound to the large ribosomal subunit
Gurel G, Blaha G, Moore PB, Steitz TA
J Mol Biol (2009) [PMID: 19362093  ]
Assembly composition: RNA/protein complex
Bound ligands: K    K    MG    SR    SR    NA    CD    CL    MG    WIN    CD    NA   
Modified residues: OMG    OMU    UR3    1MA    1MA    PSU    PSU    OMG    OMU    UR3   
Assembly name: Large ribosomal protein and RNA (Preferred)   search this complex
PDBe complex ID: PDB-CPX-145590 (Preferred)   search this ID
PDBe-KB: P14119    P29198    P14123    P10971    P32410    P12737    (view 23 more)
X-ray diffraction
2.85Å resolution
Released: 28 Apr 2009
Model geometry
Fit model/data
3g71
3g71
3g71
Co-crystal structure of Tiamulin bound to the large ribosomal subunit
Gurel G, Blaha G, Moore PB, Steitz TA
J Mol Biol (2009) [PMID: 19362093  ]
Assembly composition: RNA/protein complex
Bound ligands: K    K    MG    SR    SR    NA    CD    CL    MG    MUL    CD    NA   
Modified residues: OMG    OMU    UR3    1MA    1MA    PSU    PSU    OMG    OMU    UR3   
Assembly name: Large ribosomal protein and RNA (Preferred)   search this complex
PDBe complex ID: PDB-CPX-145588 (Preferred)   search this ID
PDBe-KB: P14119    P29198    P14123    P10971    P32410    P12737    (view 23 more)
X-ray diffraction
3.2Å resolution
Released: 28 Apr 2009
Model geometry
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3g4s
3g4s
3g4s
Structure of chloramphenicol bound to the 50S ribosomal subunit
Hansen JL, Moore PB, Steitz TA
J Mol Biol (2003) [PMID: 12860128  ]
Assembly composition: RNA/protein complex
Bound ligands: CLM    K    K    MG    CLM    NA    CD    CL    MG    CD    NA   
Assembly name: Large ribosomal protein (Preferred)   search this complex
PDBe complex ID: PDB-CPX-250165 (Preferred)   search this ID
PDBe-KB: P14119    P29198    P14123    P10971    P32410    P12737    (view 22 more)
X-ray diffraction
3Å resolution
Released: 22 Jul 2003
Model geometry
Fit model/data
1nji
1nji
1nji
Co-crystal Structure of Blasticidin S Bound to the 50S Ribosomal Subunit
Hansen JL, Ban N, Nissen P, Moore PB, Steitz TA
J Mol Biol (2003) [PMID: 12860128  ]
Assembly composition: RNA/protein complex
Bound ligands: K    K    MG    BLS    BLS    NA    CD    CL    MG    CD    NA   
Assembly name: Large ribosomal protein (Preferred)   search this complex
PDBe complex ID: PDB-CPX-250165 (Preferred)   search this ID
PDBe-KB: P14119    P29198    P14123    P10971    P32410    P12737    (view 22 more)
X-ray diffraction
3.01Å resolution
Released: 22 Jul 2003
Model geometry
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1kc8
1kc8
1kc8
Structure of Anisomycin resistant 50S Ribosomal Subunit: 23S rRNA mutation A2488C. Density for anisomycin is visible but not included in the model.
Blaha G, Gurel G
J Mol Biol (2008) [PMID: 18455733  ]
Assembly composition: RNA/protein complex
Bound ligands: K    K    MG    SR    SR    NA    CD    CL    MG    CD    NA   
Modified residues: OMG    OMU    UR3    1MA    1MA    PSU    PSU    OMG    OMU    UR3   
Assembly name: Large ribosomal protein and RNA (Preferred)   search this complex
PDBe complex ID: PDB-CPX-145581 (Preferred)   search this ID
PDBe-KB: P14119    P29198    P14123    P10971    P32410    P12737    (view 23 more)
X-ray diffraction
3Å resolution
Released: 20 May 2008
Model geometry
Fit model/data
3ccr
3ccr
3ccr
Structure of Anisomycin resistant 50S Ribosomal Subunit: 23S rRNA mutation G2616A
Blaha G, Gurel G
J Mol Biol (2008) [PMID: 18455733  ]
Assembly composition: RNA/protein complex
Bound ligands: K    K    MG    SR    SR    NA    CD    CL    MG    CD    NA   
Modified residues: OMG    OMU    UR3    1MA    1MA    PSU    PSU    OMG    OMU    UR3   
Assembly name: Large ribosomal protein and RNA (Preferred)   search this complex
PDBe complex ID: PDB-CPX-145584 (Preferred)   search this ID
PDBe-KB: P14119    P29198    P14123    P10971    P32410    P12737    (view 23 more)
X-ray diffraction
2.9Å resolution
Released: 20 May 2008
Model geometry
Fit model/data
3ccv
3ccv
3ccv
...
Entries 1 to 10 of 63
Entries 1 to 10 of 63