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X-ray diffraction
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(15)
Rayment I
(6)
Reznikoff WS
(5)
Lovell S
(4)
Goryshin IY
(3)
Davies DR
(2)
Holden HM
(2)
Klenchin VA
(2)
Steiniger-White M
(2)
Thoden JB
(2)
Bhasin A
(1)
Braam LM
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Czyz A
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Gradman R
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Mahnke Braam L
(1)
Reznikoff WR
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Homo / hetero assembly
(2)
hetero
(5)
homo
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Assembly composition
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DNA/protein complex
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protein structure
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hexamer
(5)
dimer
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Resolution distribution
1.5 - 2
(1)
2.0 - 2.5
(3)
2.5 - 3
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1995 - 2000
(1)
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(3)
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Journal
(6)
Curr Opin Struct Biol
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(6)
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Escherichia coli
(6)
Molecule name
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Tnp
(6)
Transposase for transposon Tn5
(6)
Molecule type
(1)
Protein
(6)
Gene names
(2)
tnp
(6)
tnpA
(6)
Interacting Molecules
(6)
DNA NON-TRANSFERRED STRAND
(2)
DNA TRANSFERRED STRAND
(2)
DNA non-transferred strand
(2)
DNA transferred strand
(2)
ME DNA non-transferred strand
(1)
ME DNA transferred strand
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Interacting ligands
(5)
MN : MANGANESE (II) ION
(4)
EDO : 1,2-ETHANEDIOL
(2)
MG : MAGNESIUM ION
(2)
GOL : GLYCEROL
(1)
TPT : 2,2':6',2''-TERPYRIDINE PLATINUM(II) Chloride
(1)
Function and Biology
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(4)
DNA binding
(6)
transposase activity
(6)
endonuclease activity
(5)
metal ion binding
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(6)
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transposition
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Sequence and Structure classification
SCOP fold
(1)
Ribonuclease H-like motif
(5)
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Transposase inhibitor (Tn5 transposase)
(5)
CATH class
(2)
Alpha Beta
(6)
Mainly Alpha
(6)
CATH topology
(3)
Transferase Inhibitor Protein From Tn5; Chain A, domain2
(6)
Transposase Inhibitor Protein From Tn5; Chain A, domain 1
(6)
Serum Albumin; Chain A, Domain 1
(5)
Pfam accession / name
(2)
PF01609 : DDE_Tnp_1
(6)
PF14706 : Tnp_DNA_bind
(5)
Experimental Information
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(4)
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Representative Structures
Representative Structures
Entries
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Entries 1 to 6 of 6
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TRANSPOSASE INHIBITOR
Davies DR, Braam LM, Reznikoff WS, Rayment I
J Biol Chem
(1999)
[PMID: 10207011 ]
Source organism: Escherichia coli
Assembly composition: protein only structure
Bound ligands:
TPT
Assembly name:
Transposase for transposon Tn5
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-175136 (Preferred)
search this ID
![Protein Data Bank in Europe - Knowledge Base](https://www.ebi.ac.uk/pdbe/pdbe-kb/static/icon/favicon-32x32.png)
TN5 transposase: 20MER OUTSIDE END 2 MN complex
Klenchin VA, Lovell S, Goryshin IY, Reznikoff WR, Rayment I
Nat Struct Biol
(2002)
[PMID: 11896402 ]
Source organisms: Synthetic construct, Escherichia coli
Assembly composition: DNA/protein complex
Assembly name:
Transposase for transposon Tn5 and DNA
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-117331 (Preferred)
search this ID
![Protein Data Bank in Europe - Knowledge Base](https://www.ebi.ac.uk/pdbe/pdbe-kb/static/icon/favicon-32x32.png)
Crystal Structure Of Tn5 Transposase Complexed With 5' Phosphorylated Transposon End DNA
Klenchin VA
Nucleic Acids Res
(2008)
[PMID: 18790806 ]
Source organisms: Synthetic construct, Escherichia coli
Assembly composition: DNA/protein complex
Bound ligands:
GOL
Assembly name:
Transposase for transposon Tn5 and DNA
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-116204 (Preferred)
search this ID
crystal structure of Tn5 transposase complexed with resolved outside end DNA
Holden HM, Thoden JB, Steiniger-White M, Reznikoff WS, Lovell S, Rayment I
Curr Opin Struct Biol
(2004)
[PMID: 15102449 ]
Source organisms: Synthetic construct, Escherichia coli
Assembly composition: DNA/protein complex
Assembly name:
Transposase for transposon Tn5 and DNA
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-114206 (Preferred)
search this ID
![Protein Data Bank in Europe - Knowledge Base](https://www.ebi.ac.uk/pdbe/pdbe-kb/static/icon/favicon-32x32.png)
CRYSTAL STRUCTURE OF TN5 TRANSPOSASE COMPLEXED WITH TRANSPOSON END DNA
Thoden JB, Holden HM, Davies DR, Goryshin IY, Reznikoff WS, Rayment I
Science
(2000)
[PMID: 10884228 ]
Source organisms: Synthetic construct, Escherichia coli
Assembly composition: DNA/protein complex
Assembly name:
Transposase for transposon Tn5 and DNA
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-114205 (Preferred)
search this ID
Crystal structure of Tn5 Transposase complexed with ME DNA
Steiniger-White M, Bhasin A, Lovell S, Rayment I, Reznikoff WS
J Mol Biol
(2002)
[PMID: 12367522 ]
Source organisms: Synthetic construct, Escherichia coli
Assembly composition: DNA/protein complex
Assembly name:
Transposase for transposon Tn5 and DNA
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-114192 (Preferred)
search this ID
![Protein Data Bank in Europe - Knowledge Base](https://www.ebi.ac.uk/pdbe/pdbe-kb/static/icon/favicon-32x32.png)
Entries 1 to 6 of 6