- Display observed secondary structure variance per amino acid residue
Lysine-specific demethylase 4D
Homo sapiens (Human)
JHDM3D, JMJD2D
Q6B0I6go to UniProt
Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Demethylates both di- and trimethylated H3 'Lys-9' residue, while it has no activity on monomethylated residues. Demethylation of Lys residue generates formaldehyde and succinatego to UniProt
Representative structure for UniProt Q6B0I6
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