DNA polymerase IV

Gene:

dinB Enzyme: EC 2.7.7.7 This enzyme has known catalytic activity involved in reaction: DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate

Organism:

Escherichia coli (strain K12)

Synonyms:

dinP

Uniprot:

Q47155go to UniProt

Biological function:

Poorly processive, error-prone DNA polymerase involved in translesion repair and untargeted mutagenesis (PubMed:10488344, PubMed:10801133). Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by Pol IV. Exhibits no 3'-5' exonuclease (proofreading) activity (PubMed:10488344). Overexpression of Pol IV ... [show more]go to UniProt

Representative structure for UniProt Q47155

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PDB 5c5j chain A (observed residues)
PDB 5c5j chain A (observed residues)

PDB chain shown: 5c5j A go to PDBe

UniProt residues 2 - 351

Coverage: 97%

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31
Structures

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15
Ligands

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2
Interactions

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175
Similarity

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94
Publications

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