- Display observed secondary structure variance per amino acid residue
Ubiquitin carboxyl-terminal hydrolase 7
USP7 Enzyme: EC 3.4.19.12 This enzyme has known catalytic activity involved in reaction: Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal). Disease Hao-Fountain syndrome: An autosomal dominant neurodevelopmental disorder characterized by global developmental delay, varying degrees of intellectual disability, autism spectrum disorder, poor or absent speech, and mild facial dysmorphism. Most patients develop seizures... [click for more]
Homo sapiens (Human)
HAUSP
Q93009go to UniProt
(Microbial infection) Upon infection with Epstein-Barr virus, the interaction with viral EBNA1 increases the association of USP7 with PML proteins, which is required for the polyubiquitylation and degradation of PMLgo to UniProt
Representative structures for UniProt Q93009
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Observed regions are darker shades, while unobserved regions are slightly transparent.
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