- Display observed secondary structure variance per amino acid residue
Methyl-CpG-binding protein 2
Homo sapiens (Human)
P51608go to UniProt
Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC)go to UniProt
Representative structure for UniProt P51608
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Observed regions are darker shades, while unobserved regions are slightly transparent.
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