Early protein OPG038

Gene:

OPG038

Organism:

Monkeypox virus

Synonyms:

M2L

Uniprot:

A0A7H0DN11go to UniProt

Biological function:

Plays a role in immune evasion. When secreted, inhibits T-cell activation by preventing the binding of host CD80 and CD86 to soluble CTLA4 and CD28. In the infected cell, may inhibits host NF kappa B activationgo to UniProt

Representative structure for UniProt A0A7H0DN11

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PDB 8hxb chain C (observed residues)
PDB 8hxb chain C (observed residues)

PDB chain shown: 8hxb C go to PDBe

UniProt residues 18 - 220

Coverage: 91%

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