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PAN2-PAN3 deadenylation complex subunit PAN3
PAN3
Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719) (Thermochaetoides thermophila)
G0S0Y3go to UniProt
Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely ... [show more]go to UniProt
Representative structure for UniProt G0S0Y3
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PDB chain shown: 4cyj D go to PDBe
UniProt residues 205 - 640
Coverage: 64%