- Display observed secondary structure variance per amino acid residue
Tissue-type plasminogen activator
Homo sapiens (Human)
P00750go to UniProt
Converts the abundant, but inactive, zymogen plasminogen to plasmin by hydrolyzing a single Arg-Val bond in plasminogen. By controlling plasmin-mediated proteolysis, it plays an important role in tissue remodeling and degradation, in cell migration and many other physiopathological events. During oocyte activation, plays a role in cortical granule reaction in the zona reaction, which contributes to the block to polyspermy ... [show more]go to UniProt
Representative structures for UniProt P00750
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PDB chain shown: 1tpm A go to PDBe
UniProt residues 36 - 85
Coverage: 9%
Processed Proteins (2):
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UniProt range of representative PDB 1tpm chain A: 36 - 85
UniProt range of representative PDB 1rtf chain B: 311 - 562