- Display observed secondary structure variance per amino acid residue
Interferon beta
Ifnb1
Mus musculus (Mouse)
Ifb, Ifnb
P01575go to UniProt
Type I interferon cytokine that plays a key role in the innate immune response to infection, developing tumors and other inflammatory stimuli (PubMed:10708458, PubMed:23872679). Signals via binding to high-affinity (IFNAR2) and low-affinity (IFNAR1) heterodimeric receptor, activating the canonical Jak-STAT signaling pathway resulting in transcriptional activation or repression of interferon-regulated genes that encode the effectors ... [show more]go to UniProt
Representative structure for UniProt P01575
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PDB chain shown: 1wu3 A go to PDBe
UniProt residues 22 - 182
Coverage: 88%