DNA-binding transcriptional dual regulator ModE

Gene:

modE

Organism:

Escherichia coli (strain K12)

Synonyms:

modR

Uniprot:

P0A9G8go to UniProt

Biological function:

Functions as an intracellular molybdate sensor. The ModE-Mo complex acts as a repressor of the modABC operon, which is involved in the transport of molybdate (PubMed:8550508). Binds modA promoter DNA in the absence of molybdate, however molybdate binding confers increased DNA affinity (PubMed:9044285, PubMed:9210473). Binds the promoter of moaA activating its ... [show more]go to UniProt

Representative structure for UniProt P0A9G8

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PDB 1b9m chain B (observed residues)
PDB 1b9m chain B (observed residues)
PDB 1b9m chain B (observed residues)
PDB 1b9m chain B (observed residues)
PDB 1b9m chain B (observed residues)
PDB 1b9m chain B (observed residues)

PDB chain shown: 1b9m B go to PDBe

UniProt residues 1 - 262

Coverage: 94%

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