NADH-quinone oxidoreductase subunit A

Gene:

nuoA Enzyme: EC 7.1.1.- This enzyme has known catalytic activity involved in reaction: a quinone + NADH + 5 H(+)(in) = a quinol + NAD(+) + 4 H(+)(out)

Organism:

Escherichia coli (strain K12)

Uniprot:

P0AFC3go to UniProt

Biological function:

NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in ... [show more]go to UniProt

Representative structure for UniProt P0AFC3

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PDB 7p69 chain H (observed residues)
PDB 7p69 chain H (observed residues)
PDB 7p69 chain H (observed residues)
PDB 7p69 chain H (observed residues)

PDB chain shown: 7p69 H go to PDBe

UniProt residues 1 - 147

Coverage: 69%

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24
Structures

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11
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135
Similarity

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18
Publications

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