Peptidyl-prolyl cis-trans isomerase

Gene:

CPR1 Enzyme: EC 5.2.1.8 This enzyme has known catalytic activity involved in reaction: [protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)

Organism:

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Synonyms:

CPH1, CYP1, SCC1

Uniprot:

P14832go to UniProt

Biological function:

PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Involved in histone deacetylase complexes, suggesting a function in chromatin. Imports fructose-1,6-bisphosphatase (FBPase) into the intermediate vacuole import and degradation (Vid) vesicles. Regulates the meiotic gene program via the Set3C histone deacetylase complex to promote efficient sporulation, and the prolyl-isomerase activity is ... [show more]go to UniProt

Representative structure for UniProt P14832

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PDB 9cf1 chain A (observed residues)
PDB 9cf1 chain A (observed residues)

PDB chain shown: 9cf1 A go to PDBe

UniProt residues 1 - 162

Coverage: 100%

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19
Similarity

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