General transcription and DNA repair factor IIH subunit TFB1 (P32776)

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PDB publications (14)
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Transcription start site scanning requires the fungi-specific hydrophobic loop of Tfb3.
Yang C, Basnet P, Sharmin S, Shen H, Kaplan CD et al.
Nucleic Acids Res (2024)
Related PDB entries: 8uoq go to PDBe,  8uot go to PDBe 
Yeast PIC-Mediator structure with RNA polymerase II C-terminal domain.
Schilbach S, Wang H, Dienemann C, Cramer P
Proc Natl Acad Sci U S A 15 e2220542120 (2023)
Related PDB entries: 8cen go to PDBe,  8ceo go to PDBe 
Structural visualization of de novo transcription initiation by Saccharomyces cerevisiae RNA polymerase II.
Yang C, Fujiwara R, Kim HJ, Basnet P, Zhu Y et al.
Mol Cell 3 660-676.e9 (2022)
Related PDB entries: 7ml0 go to PDBe,  7ml1 go to PDBe,  7ml2 go to PDBe,  7ml3 go to PDBe,  7ml4 go to PDBe 
Structures of transcription preinitiation complex engaged with the +1 nucleosome.
Wang H, Schilbach S, Ninov M, Urlaub H, Cramer P et al.
Nat Struct Mol Biol (2022)
Related PDB entries: 7zs9 go to PDBe,  7zsa go to PDBe,  7zsb go to PDBe 
Cryo-EM structure of TFIIH/Rad4-Rad23-Rad33 in damaged DNA opening in nucleotide excision repair.
van Eeuwen T, Shim Y, Kim HJ, Zhao T, Basu S et al.
Nat Commun 1 3338 (2021)
Related PDB entries: 7k01 go to PDBe,  7k04 go to PDBe,  7m2u go to PDBe 
Structure of RNA polymerase II pre-initiation complex at 2.9 Å defines initial DNA opening.
Schilbach S, Aibara S, Dienemann C, Grabbe F, Cramer P et al.
Cell 15 4064-4072.e28 (2021)
Related PDB entries: 7o4i go to PDBe,  7o4j go to PDBe,  7o4k go to PDBe,  7o4l go to PDBe,  7o72 go to PDBe,  7o73 go to PDBe,  7o75 go to PDBe 
Structural characterization of interactions between transactivation domain 1 of the p65 subunit of NF-κB and transcription regulatory factors.
Lecoq L, Raiola L, Chabot PR, Cyr N, Arseneault G et al.
Nucleic Acids Res 9 5564-5576 (2017)
Related PDB entries: 5urn go to PDBe 
A ΩXaV motif in the Rift Valley fever virus NSs protein is essential for degrading p62, forming nuclear filaments and virulence.
Cyr N, de la Fuente C, Lecoq L, Guendel I, Chabot PR et al.
Proc Natl Acad Sci U S A 19 6021-6 (2015)
Related PDB entries: 2n0y go to PDBe 
Structural and functional characterization of a complex between the acidic transactivation domain of EBNA2 and the Tfb1/p62 subunit of TFIIH.
Chabot PR, Raiola L, Lussier-Price M, Morse T, Arseneault G et al.
PLoS Pathog 3 e1004042 (2014)
Related PDB entries: 2mkr go to PDBe 
Structural and functional evidence that Rad4 competes with Rad2 for binding to the Tfb1 subunit of TFIIH in NER.
Lafrance-Vanasse J, Arseneault G, Cappadocia L, Legault P, Omichinski JG et al.
Nucleic Acids Res 4 2736-45 (2013)
Related PDB entries: 2m14 go to PDBe 
PDB-related reviews (75)
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The role of Transcription Factor IIH complex in nucleotide excision repair.
Related PDB entries: 7k01 go to PDBe,  7k04 go to PDBe,  7m2u go to PDBe 
The molecular basis for cellular function of intrinsically disordered protein regions.
Related PDB entries: 2gs0 go to PDBe 
A Revision of Herpes Simplex Virus Type 1 Transcription: First, Repress; Then, Express.
Related PDB entries: 7ml0 go to PDBe,  7ml1 go to PDBe,  7ml2 go to PDBe,  7ml3 go to PDBe,  7ml4 go to PDBe 
Protein-protein interactions in the core nucleotide excision repair pathway.
Related PDB entries: 7k01 go to PDBe,  7k04 go to PDBe,  7m2u go to PDBe 
Regulation of ribosomal RNA gene copy number, transcription and nucleolus organization in eukaryotes.
Related PDB entries: 7o4i go to PDBe,  7o4j go to PDBe,  7o4k go to PDBe,  7o4l go to PDBe,  7o72 go to PDBe,  7o73 go to PDBe,  7o75 go to PDBe 
Interaction modules that impart specificity to disordered protein.
Related PDB entries: 2gs0 go to PDBe 
Opposing Roles of FACT for Euchromatin and Heterochromatin in Yeast.
Related PDB entries: 7zs9 go to PDBe,  7zsa go to PDBe,  7zsb go to PDBe 
Targeting p53 pathways: mechanisms, structures, and advances in therapy.
Related PDB entries: 2gs0 go to PDBe 
Epstein-Barr Virus B Cell Growth Transformation: The Nuclear Events.
Related PDB entries: 2mkr go to PDBe 
Regulation of the RNA polymerase II pre-initiation complex by its associated coactivators.
Related PDB entries: 2gs0 go to PDBe,  7o4i go to PDBe,  7o4j go to PDBe,  7o4k go to PDBe,  7o4l go to PDBe,  7o72 go to PDBe,  7o73 go to PDBe,  7o75 go to PDBe,  8cen go to PDBe,  8ceo go to PDBe 
UniProt publications (13)
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The reference genome sequence of Saccharomyces cerevisiae: Then and now.
Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R. et al.
G3 (Bethesda) 389-398 (2014)
Structural and functional evidence that Rad4 competes with Rad2 for binding to the Tfb1 subunit of TFIIH in NER.
Lafrance-Vanasse J., Arseneault G., Cappadocia L., Legault P., Omichinski J.G. et al.
Nucleic Acids Res. 2736-2745 (2013)
Tfb6, a previously unidentified subunit of the general transcription factor TFIIH, facilitates dissociation of Ssl2 helicase after transcription initiation.
Murakami K., Gibbons B.J., Davis R.E., Nagai S., Liu X. et al.
Proc. Natl. Acad. Sci. U.S.A. 4816-4821 (2012)
Structural and functional characterization of interactions involving the Tfb1 subunit of TFIIH and the NER factor Rad2.
Lafrance-Vanasse J., Arseneault G., Cappadocia L., Chen H.T., Legault P. et al.
Nucleic Acids Res. 5739-5750 (2012)
A multidimensional chromatography technology for in-depth phosphoproteome analysis.
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J. et al.
Mol. Cell. Proteomics 1389-1396 (2008)
Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae.
Hu Y., Rolfs A., Bhullar B., Murthy T.V., Zhu C. et al.
Genome Res. 536-543 (2007)
Revised subunit structure of yeast transcription factor IIH (TFIIH) and reconciliation with human TFIIH.
Takagi Y., Komori H., Chang W.-H., Hudmon A., Erdjument-Bromage H. et al.
J. Biol. Chem. 43897-43900 (2003)
Global analysis of protein expression in yeast.
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A. et al.
Nature 737-741 (2003)
The nucleotide sequence of Saccharomyces cerevisiae chromosome IV.
Jacq C., Alt-Morbe J., Andre B., Arnold W., Bahr A. et al.
Nature 75-78 (1997)
PMID: 9169867
Reconstitution of TFIIH and requirement of its DNA helicase subunits, Rad3 and Rad25, in the incision step of nucleotide excision repair.
Sung P., Guzder S.N., Prakash L., Prakash S.
J. Biol. Chem. 10821-10826 (1996)
PMID: 8631896