Histone acetyltransferase RTT109

Gene:

RTT109 Enzyme: EC 2.3.1.48 This enzyme has known catalytic activity involved in reaction: L-lysyl-[protein] + acetyl-CoA = N(6)-acetyl-L-lysyl-[protein] + CoA + H(+)

Organism:

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Synonyms:

KAT11, KIM2, REM50

Uniprot:

Q07794go to UniProt

Biological function:

Histone chaperone-dependent acetylase that modifies 'Lys-9', 'Lys-14', 'Lys-23', 'Lys-27', and 'Lys-56' on histone H3 (H3K9Ac, H3K14Ac and H3K23Ac, H3K27Ac, and H3K56Ac) to promote nucleosome assembly, genomic stability, DNA repair and transcriptional regulation during mitotic S-phase (PubMed:17046836, PubMed:17272723, PubMed:17320445, PubMed:17369253, PubMed:18723682, PubMed:19172748, [show more]go to UniProt

Representative structure for UniProt Q07794

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PDB 2rim chain A (observed residues)
PDB 2rim chain A (observed residues)
PDB 2rim chain A (observed residues)
PDB 2rim chain A (observed residues)

PDB chain shown: 2rim A go to PDBe

UniProt residues 1 - 436

Coverage: 85%

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10
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84
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