Aldehyde dehydrogenase, cytosolic 1

Gene:

ALDH1 Enzyme: EC 1.2.1.3 This enzyme has known catalytic activity involved in reaction: an aldehyde + NAD(+) + H2O = a carboxylate + NADH + 2 H(+)

Organism:

Elephantulus edwardii (Cape long-eared elephant shrew)

Uniprot:

Q28399go to UniProt

Biological function:

Major component of the eye of elephant shrews, which in contrast to other mammals, possesses both a lens- and a non-lens class-1 aldehyde dehydrogenase 1. This eye-specific form is a structural protein of the lens and, in other part of the eye, serves as the major form of ALDH1. Can convert/oxidize retinaldehyde to retinoic acidgo to UniProt

Representative structure for UniProt Q28399

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PDB 1o9j chain D (observed residues)
PDB 1o9j chain D (observed residues)

PDB chain shown: 1o9j D go to PDBe

UniProt residues 1 - 501

Coverage: 99%

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