Large ribosomal subunit protein uL6 (Q2FW21)

Publications
Primary PDB publications, reviews associated with PDB entries and UniProt publications are listed below. Click on the plus/minus signs to expand/collapse the publication lists.
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PDB publications (10)
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Structures of the Staphylococcus aureus ribosome inhibited by fusidic acid and fusidic acid cyclopentane.
González-López A, Larsson DSD, Koripella RK, Cain BN, Chavez MG et al.
Sci Rep 1 14253 (2024)
Related PDB entries: 8p2f go to PDBe,  8p2g go to PDBe,  8p2h go to PDBe 
Synthetic macrolides overcoming MLSBK-resistant pathogens.
Ma CX, Li Y, Liu WT, Li Y, Zhao F et al.
Cell Discov 1 75 (2024)
Related PDB entries: 8y36 go to PDBe,  8y37 go to PDBe,  8y38 go to PDBe,  8y39 go to PDBe 
Structural basis of ABCF-mediated resistance to pleuromutilin, lincosamide, and streptogramin A antibiotics in Gram-positive pathogens.
Crowe-McAuliffe C, Murina V, Turnbull KJ, Kasari M, Mohamad M et al.
Nat Commun 1 3577 (2021)
Related PDB entries: 7nhl go to PDBe,  7nhm go to PDBe 
Characterization of the Core Ribosomal Binding Region for the Oxazolidone Family of Antibiotics Using Cryo-EM.
Wright A, Deane-Alder K, Marschall E, Bamert R, Venugopal H et al.
ACS Pharmacol Transl Sci 3 425-432 (2020)
Related PDB entries: 6wru go to PDBe 
Structural Basis for Linezolid Binding Site Rearrangement in the Staphylococcus aureus Ribosome.
Belousoff MJ, Eyal Z, Radjainia M, Ahmed T, Bamert RS et al.
mBio 3 (2017)
Related PDB entries: 5tcu go to PDBe 
Structural insights of lincosamides targeting the ribosome of Staphylococcus aureus.
Matzov D, Eyal Z, Benhamou RI, Shalev-Benami M, Halfon Y et al.
Nucleic Acids Res 17 10284-10292 (2017)
Related PDB entries: 5hkv go to PDBe,  5nrg go to PDBe 
Structures and dynamics of hibernating ribosomes from Staphylococcus aureus mediated by intermolecular interactions of HPF.
Khusainov I, Vicens Q, Ayupov R, Usachev K, Myasnikov A et al.
EMBO J 14 2073-2087 (2017)
Related PDB entries: 5nd8 go to PDBe,  5nd9 go to PDBe 
A novel pleuromutilin antibacterial compound, its binding mode and selectivity mechanism.
Eyal Z, Matzov D, Krupkin M, Paukner S, Riedl R et al.
Sci Rep 39004 (2016)
Related PDB entries: 5hl7 go to PDBe 
Structure of the 70S ribosome from human pathogen Staphylococcus aureus.
Khusainov I, Vicens Q, Bochler A, Grosse F, Myasnikov A et al.
Nucleic Acids Res 21 10491-10504 (2016)
Related PDB entries: 5li0 go to PDBe 
Structural insights into species-specific features of the ribosome from the pathogen Staphylococcus aureus.
Eyal Z, Matzov D, Krupkin M, Wekselman I, Paukner S et al.
Proc Natl Acad Sci U S A 43 E5805-14 (2015)
Related PDB entries: 4wce go to PDBe,  4wf9 go to PDBe,  4wfa go to PDBe,  4wfb go to PDBe,  6hma go to PDBe 
PDB-related reviews (58)
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One-pot chemoenzymatic syntheses of non-canonical amino acids.
Related PDB entries: 5nrg go to PDBe 
Treatment of MRSA Infection: Where are We?
Related PDB entries: 5hl7 go to PDBe 
Scientific Rationale and Clinical Basis for Clindamycin Use in the Treatment of Dermatologic Disease.
Related PDB entries: 7nhl go to PDBe,  7nhm go to PDBe 
Recent development and fighting strategies for lincosamide antibiotic resistance.
Related PDB entries: 4wce go to PDBe,  4wfa go to PDBe,  4wfb go to PDBe,  5nrg go to PDBe 
Advances in contezolid: novel oxazolidinone antibacterial in Gram-positive treatment.
Related PDB entries: 6wru go to PDBe 
Clindamycin: A Comprehensive Status Report with Emphasis on Use in Dermatology.
Related PDB entries: 5nrg go to PDBe 
Molecular mechanisms of antibiotic resistance revisited.
Related PDB entries: 7nhl go to PDBe,  7nhm go to PDBe 
The Discovery of Ribosomal Protein bL31 from Escherichia coli: A Long Story Revisited.
Related PDB entries: 5nd8 go to PDBe,  5nd9 go to PDBe 
A Comprehensive Overview of the Antibiotics Approved in the Last Two Decades: Retrospects and Prospects.
Related PDB entries: 6wru go to PDBe 
Antibiotics and Bacterial Resistance-A Short Story of an Endless Arms Race.
Related PDB entries: 4wce go to PDBe,  4wf9 go to PDBe,  4wfa go to PDBe,  4wfb go to PDBe 
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