Centromere protein U

Gene:

CENPU

Organism:

Homo sapiens (Human)

Synonyms:

ICEN24, KLIP1, MLF1IP, PBIP1

Uniprot:
Biological function:

Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. Plays an important role in the correct PLK1 localization to the mitotic kinetochores. A scaffold protein ... [show more]go to UniProt


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PDB 7pkn chain J (observed residues)
PDB 7pkn chain J (observed residues)

PDB chain shown: 7pkn J go to PDBe

UniProt residues 1 - 418

Coverage: 40%

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10
Structures

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6
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11
Similarity

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25
Publications

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