N-glycosylase/DNA lyase

Organism:

Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)

Uniprot:

Q8U2D5go to UniProt

Biological function:

DNA repair enzyme that is part of the base excision repair (BER) pathway; protects from oxidative damage by removing the major product of DNA oxidation, 8-oxoguanine (GO), from single- and double-stranded DNA substratesgo to UniProt

Representative structure for UniProt Q8U2D5

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PDB 1xg7 chain A (observed residues)
PDB 1xg7 chain A (observed residues)

PDB chain shown: 1xg7 A go to PDBe

UniProt residues 2 - 242

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9
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