Histone-lysine N-methyltransferase SUVR4

Gene:

SUVR4 Enzyme: EC 2.1.1.- This enzyme has known catalytic activity involved in reaction: N(6),N(6)-dimethyl-L-lysyl(9)-[histone H3] + S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(9)-[histone H3] + S-adenosyl-L-homocysteine + H(+)

Organism:

Arabidopsis thaliana (Mouse-ear cress)

Synonyms:

SDG31, SET31

Uniprot:

Q8W595go to UniProt

Biological function:

Histone methyltransferase that converts monomethylated 'Lys-9' of histone H3 (H3K9me1) to dimethylated 'Lys-9' (H3K9me2) in the absence of bound ubiquitin, and to trimethylated 'Lys-9' (H3K9me3) in the presence of bound ubiquitin. Acts in a locus-specific manner and contributes to the transcriptional silencing of pseudogenes and transposons. H3 'Lys-9' methylation represents a specific tag for epigenetic transcriptional repressiongo to UniProt

Representative structure for UniProt Q8W595

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PDB 2lxe chain A (observed residues)
PDB 2lxe chain A (observed residues)

PDB chain shown: 2lxe A go to PDBe

UniProt residues 1 - 89

Coverage: 18%

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