DNA double-strand break repair helicase HerA

Gene:

herA Enzyme: EC 3.6.4.12 This enzyme has known catalytic activity involved in reaction: ATP + H2O = ADP + phosphate + H(+)

Organism:

Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus)

Uniprot:

Q97WG8go to UniProt

Biological function:

Involved in DNA double-strand break (DSB) repair (PubMed:22135300). Acts probably with NurA to stimulate resection of the 5' strand and produce the long 3' single-strand that is required for RadA loading (By similarity). Exhibits DNA-dependent ATPase activity and DNA helicase activity (PubMed:22135300, PubMed:25420454)go to UniProt

Representative structure for UniProt Q97WG8

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PDB 4d2i chain A (observed residues)
PDB 4d2i chain A (observed residues)
PDB 4d2i chain A (observed residues)
PDB 4d2i chain A (observed residues)

PDB chain shown: 4d2i A go to PDBe

UniProt residues 1 - 500

Coverage: 93%

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