Phosphopantothenoylcysteine decarboxylase

Gene:

HAL3A Enzyme: EC 4.1.1.36 This enzyme has known catalytic activity involved in reaction: N-[(R)-4-phosphopantothenoyl]-L-cysteine + H(+) = (R)-4'-phosphopantetheine + CO2

Organism:

Arabidopsis thaliana (Mouse-ear cress)

Synonyms:

COAC1

Uniprot:

Q9SWE5go to UniProt

Biological function:

Involved in plant growth, and salt and osmotic tolerance (PubMed:10652125). Catalyzes the decarboxylation of 4'-phosphopantothenoylcysteine to 4'-phosphopantetheine, a key step in coenzyme A biosynthesis (PubMed:11279129, PubMed:11923307, PubMed:12860978, PubMed:16415216). The enzyme is also able to decarboxylate pantothenoylcysteine to pantothenoylcysteamine (PubMed:11923307)go to UniProt

Representative structure for UniProt Q9SWE5

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PDB 1mvl chain A (observed residues)
PDB 1mvl chain A (observed residues)
PDB 1mvl chain A (observed residues)
PDB 1mvl chain A (observed residues)

PDB chain shown: 1mvl A go to PDBe

UniProt residues 1 - 209

Coverage: 83%

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21
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