foldFAD/NAD(P)-binding domain
superfamily
View {link.id} in {link.name}
Thioredoxin reductase-like
SCOP ID: 3000050
duplication of the core domain accompanied by segment-swapping; the N-terminal domain has an interrupted canonical fold and binds FAD, whereas the C-terminal domain has a circularly permuted fold (SCOP ID 2000034) and, in some members, binds NAD(P)
relations
repeated domain: Thioredoxin reductase-like half-domain
hyperfamily: FAD/NAD(P)-binding domain
Families [ 4 entries ]
Thioredoxin reductase/Flavin-dependent monoxygenase-like
SCOP ID 4000117Structure Viewer
Glutathione reductase-like
SCOP ID 4000121Structure Viewer
Adrenodoxin reductase-like
SCOP ID 4000129Structure Viewer
the characteristic meander beta-sheet, connecting strands 3 and 4 of the main beta-sheet, is replaced with alpha-helix in the N-terminal domain, but remains in the C-terminal domain
Flavocytochrome c sulfide dehydrogenase
SCOP ID 4000130Structure Viewer
Domains [ 44 entries ]
ID
Region
Links
ProteinDihydropyrimidine dehydrogenase [NADP(+)]
SpeciesSus scrofa
Q28943
187-512
UniProt
Representative domain 8017506Structure Viewer
Represented structures [ 39 ]
1H7W
A:187-512
PDBe
RCSB PDB
ProteinGlutathione reductase, mitochondrial
SpeciesHomo sapiens
P00390
62-407
UniProt
Representative domain 8001320Structure Viewer
Represented structures [ 27 ]
3GRS
A:18-363
PDBe
RCSB PDB
ProteinThioredoxin reductase 1, cytoplasmic
SpeciesRattus norvegicus
O89049
10-361
UniProt
Representative domain 8056199Structure Viewer
Represented structures [ 21 ]
1H6V
A:10-361
PDBe
RCSB PDB
ProteinApoptosis-inducing factor 1, mitochondrial
SpeciesHomo sapiens
O95831
128-472
UniProt
Representative domain 8056226Structure Viewer
Represented structures [ 18 ]
1M6I
A:128-472
PDBe
RCSB PDB
Protein2-oxopropyl-CoM reductase, carboxylating
SpeciesXanthobacter autotrophicus Py2
Q56839
2-378
UniProt
Representative domain 8056205Structure Viewer
Represented structures [ 15 ]
1MO9
A:2-378
PDBe
RCSB PDB
ProteinTrypanothione reductase
SpeciesCrithidia fasciculata
P39040
2-353
UniProt
Representative domain 8056214Structure Viewer
Represented structures [ 13 ]
1FEC
A:1-352
PDBe
RCSB PDB
ProteinPhenylacetone monooxygenase
SpeciesThermobifida fusca YX
Q47PU3
10-469
UniProt
Representative domain 8057764Structure Viewer
Represented structures [ 13 ]
1W4X
A:10-469
PDBe
RCSB PDB
ProteinApoptosis-inducing factor 1, mitochondrial
SpeciesMus musculus
Q9Z0X1
122-471
UniProt
Representative domain 8044630Structure Viewer
Represented structures [ 11 ]
1GV4
A:122-471
PDBe
RCSB PDB
ProteinFerredoxin reductase
SpeciesPseudomonas sp. KKS102
Q52437
5-309
UniProt
Representative domain 8056220Structure Viewer
Represented structures [ 10 ]
1D7Y
A:5-309
PDBe
RCSB PDB
ProteinTrimethylamine dehydrogenase
SpeciesMethylophilus methylotrophus
P16099
389-697
UniProt
Representative domain 8017579Structure Viewer
Represented structures [ 9 ]
1DJN
A:388-696
PDBe
RCSB PDB
ProteinTrypanothione reductase
SpeciesTrypanosoma cruzi
P28593
3-353
UniProt
Representative domain 8056217Structure Viewer
Represented structures [ 9 ]
1AOG
A:3-353
PDBe
RCSB PDB
ProteinThioredoxin reductase
SpeciesEscherichia coli K-12
P0A9P4
2-317
UniProt
Representative domain 8001227Structure Viewer
Represented structures [ 7 ]
1TDE
A:1-316
PDBe
RCSB PDB
ProteinGlutathione reductase
SpeciesEscherichia coli K-12
P06715
3-329
UniProt
Representative domain 8056211Structure Viewer
Represented structures [ 7 ]
1GER
A:3-329
PDBe
RCSB PDB
ProteinNADH peroxidase
SpeciesEnterococcus faecalis V583
P37062
1-316
UniProt
Representative domain 8056223Structure Viewer
Represented structures [ 7 ]
1NHP
A:1-316
PDBe
RCSB PDB
ProteinThiol-specific monooxygenase
SpeciesSchizosaccharomyces pombe 972h-
Q9HFE4
3-360
UniProt
Representative domain 8057762Structure Viewer
Represented structures [ 7 ]
2GVC
A:3-360
PDBe
RCSB PDB
ProteinNADPH:adrenodoxin oxidoreductase, mitochondrial
SpeciesBos taurus
P08165
38-432
UniProt
Representative domain 8001453Structure Viewer
Represented structures [ 6 ]
1CJC
A:6-400
PDBe
RCSB PDB
ProteinPutidaredoxin reductase CamA
SpeciesPseudomonas putida
P16640
2-319
UniProt
Representative domain 8056202Structure Viewer
Represented structures [ 5 ]
1Q1R
A:2-319
PDBe
RCSB PDB
ProteinAlkyl hydroperoxide reductase subunit F
SpeciesEscherichia coli K-12
P35340
212-521
UniProt
Representative domain 8057768Structure Viewer
Represented structures [ 5 ]
1FL2
A:212-521
PDBe
RCSB PDB
ProteinThioredoxin reductase
SpeciesGloeobacter violaceus PCC 7421
Q7NMP6
2-316
UniProt
Representative domain 8075443Structure Viewer
Represented structures [ 5 ]
5J60
C:2-316
PDBe
RCSB PDB
ProteinSarcosine oxidase subunit alpha
SpeciesCorynebacterium sp. U-96
Q50LF0
120-446
UniProt
Representative domain 8091769Structure Viewer
Represented structures [ 5 ]
1X31
A:119-445
PDBe
RCSB PDB
ProteinNADPH-ferredoxin reductase FprA
SpeciesMycobacterium tuberculosis H37Rv
P9WIQ3
2-394
UniProt
Representative domain 8056253Structure Viewer
Represented structures [ 4 ]
1LQT
B:2-394
PDBe
RCSB PDB
ProteinDihydrolipoyl dehydrogenase, mitochondrial
SpeciesPisum sativum
P31023
35-373
UniProt
Representative domain 8056233Structure Viewer
Represented structures [ 3 ]
1DXL
A:4-342
PDBe
RCSB PDB
ProteinDihydrolipoyl dehydrogenase, mitochondrial
SpeciesSaccharomyces cerevisiae S288C
P09624
22-372
UniProt
Representative domain 8056237Structure Viewer
Represented structures [ 3 ]
1V59
A:1-351
PDBe
RCSB PDB
ProteinThioredoxin reductase
SpeciesChlamydomonas reinhardtii
A0A2K3E888
63-378
UniProt
Representative domain 8106052Structure Viewer
Represented structures [ 2 ]
7P9E
B:1-316
PDBe
RCSB PDB
ProteinSulfide dehydrogenase [flavocytochrome c] flavoprotein chain
SpeciesAllochromatium vinosum DSM 180
Q06530
31-357
UniProt
Representative domain 8001476Structure Viewer
Represented structures [ 1 ]
1FCD
A:1-327
PDBe
RCSB PDB
ProteinNAD(P)H dehydrogenase (quinone)
SpeciesMycobacterium tuberculosis H37Rv
P9WHH7
2-342
UniProt
Representative domain 8044624Structure Viewer
Represented structures [ 1 ]
1XDI
A:2-342
PDBe
RCSB PDB
ProteinDihydrolipoyl dehydrogenase
SpeciesGeobacillus stearothermophilus
P11959
7-339
UniProt
Representative domain 8056229Structure Viewer
Represented structures [ 1 ]
1EBD
A:7-339
PDBe
RCSB PDB
ProteinDihydrolipoyl dehydrogenase
SpeciesPseudomonas fluorescens
P14218
2-344
UniProt
Representative domain 8056243Structure Viewer
Represented structures [ 1 ]
1LPF
A:1-343
PDBe
RCSB PDB
ProteinDihydrolipoyl dehydrogenase
SpeciesAzotobacter vinelandii
P18925
2-344
UniProt
Representative domain 8056246Structure Viewer
Represented structures [ 1 ]
3LAD
A:1-343
PDBe
RCSB PDB
ProteinDihydrolipoyl dehydrogenase
SpeciesNeisseria meningitidis
Q51225
112-460
UniProt
Representative domain 8057744Structure Viewer
Represented structures [ 1 ]
1OJT
A:117-465
PDBe
RCSB PDB
ProteinThioredoxin reductase
SpeciesHordeum vulgare subsp. vulgare
A9LN30
6-323
UniProt
Representative domain 8075429Structure Viewer
Represented structures [ 1 ]
2WHD
A:6-323
PDBe
RCSB PDB
ProteinHeterotetrameric sarcosine oxidase alpha-subunit
SpeciesStenotrophomonas maltophilia
Q3ZDQ8
120-445
UniProt
Representative domain 8091758Structure Viewer
Represented structures [ 1 ]
2GAG
A:120-445
PDBe
RCSB PDB
ProteinThioredoxin reductase
SpeciesBacillus cereus ATCC 14579
Q815J1
4-318
UniProt
Representative domain 8104337Structure Viewer
Represented structures [ 1 ]
7AAW
A:4-318
PDBe
RCSB PDB
ProteinAlkyl hydroperoxide reductase subunit F
SpeciesSalmonella enterica subsp. enterica serovar Typhimurium str. LT2
P19480
199-521
UniProt
Representative domain 8001479Structure Viewer
1HYU
A:199-521
PDBe
RCSB PDB
Protein2,4-dienoyl-CoA reductase [(2E)-enoyl-CoA-producing]
SpeciesEscherichia coli K-12
P42593
374-671
UniProt
Representative domain 8017588Structure Viewer
1PS9
A:373-670
PDBe
RCSB PDB
ProteinNAD(P)H:rubredoxin oxidoreductase
SpeciesPyrococcus furiosus DSM 3638
Q8U1K9
2-289
UniProt
Representative domain 8056196Structure Viewer
1XHC
A:2-289
PDBe
RCSB PDB
ProteinGlutathione reductase
SpeciesPlasmodium falciparum K1
Q94655
2-371
UniProt
Representative domain 8056208Structure Viewer
1ONF
A:1-370
PDBe
RCSB PDB
ProteinDihydrolipoyl dehydrogenase
SpeciesPseudomonas putida
P09063
2-331
UniProt
Representative domain 8056240Structure Viewer
1LVL
A:1-330
PDBe
RCSB PDB
ProteinThioredoxin reductase 1, mitochondrial
SpeciesArabidopsis thaliana
Q39243
46-367
UniProt
Representative domain 8057766Structure Viewer
1VDC
A:1-316
PDBe
RCSB PDB
ProteinThioredoxin reductase
SpeciesClostridium acetobutylicum ATCC 824
Q97IU2
1-287
UniProt
Representative domain 8075453Structure Viewer
6GNC
A:1-287
PDBe
RCSB PDB
ProteinFlavocytochrome c flavin subunit
SpeciesThermochromatium tepidum
D0G7Q4
32-357
UniProt
Representative domain 8084465Structure Viewer
3VRD
B:2-327
PDBe
RCSB PDB
ProteinCytochrome C
SpeciesThioalkalivibrio paradoxus ARh 1
W0DP88
37-358
UniProt
Representative domain 8084467Structure Viewer
5N1T
A:33-354
PDBe
RCSB PDB
ProteinUncharacterized protein
SpeciesPyrococcus horikoshii OT3
O59088
103-394
UniProt
Representative domain 8091752Structure Viewer
1Y56
A:101-392
PDBe
RCSB PDB
ProteinThioredoxin reductase
SpeciesThermosipho africanus TCF52B
B7ICV3
12-316
UniProt
Representative domain 8105395Structure Viewer
7JYP
A:12-316
PDBe
RCSB PDB