superfamilySARS coronavirus NSP9 RNA-replicase
domain
5C94 A:1-111
SCOP ID: 8076495
Replicase polyprotein 1ab
Species Avian infectious bronchitis virus (strain M41)
UniProtP0C6Y3
This domain
 
MASSLKQGVS PKLRDVILVS KDIPEQLCDA LFFYTSHNPK DYADAFAVRQ KFDRNLQTGK QFKFETVCGL FLLKGVDKIT PGVPAKVLKA TSKLADLEDI FGVSPFARKY RELLKTACQW SLTVETLDAR AQTLDEIFDP TEILWLQVAA KIQVSAMAMR RLVGEVTAKV MDALGSNMSA LFQIFKQQIV RIFQKALAIF ENVSELPQRI AALKMAFAKC AKSITVVVME RTLVVREFAG TCLASINGAV AKFFEELPNG FMGAKIFTTL AFFREAAVKI VDNIPNAPRG TKGFEVVGNA KGTQVVVRGM RNDLTLLDQK AEIPVESEGW SAILGGHLCY VFKSGDRFYA APLSGNFALH DVHCCERVVC LSDGVTPEIN DGLILAAIYS SFSVAELVAA IKRGEPFKFL GHKFVYAKDA AVSFTLAKAA TIADVLKLFQ SARVKVEDVW SSLTEKSFEF WRLAYGKVRN LEEFVKTCFC KAQMAIVILA TVLGEGIWHL VSQVIYKVGG LFTKVVDFCE KYWKGFCAQL KRAKLIVTET LCVLKGVAQH CFQLLLDAIQ FMYKSFKKCA LGRIHGDLLF WKGGVHKIIQ EGDEIWFDAI DSIDVEDLGV VQEKLIDFDV CDNVTLPENQ PGHMVQIEDD GKNYMFFRFK KDENIYYTPM SQLGAINVVC KAGGKTVTFG ETTVQEIPPP DVVFIKVSIE CCGEPWNTIF KKAYKEPIEV ETDLTVEQLL SVVYEKMCDD LKLFPEAPEP PPFENVTLVD KNGKDLDCIK SCHLIYRDYE SDDDIEEEDA EECDTDSGDA EECDTNLECE EEDEDTKVLA LIQDPASNKY PLPLDDDYSV YNGCIVHKDA LDVVNLPSGE ETFVVNNCFE GAVKALPQKV IDVLGDWGEA VDAQEQLCQQ ESTRVISEKS VEGFTGSCDA MAEQAIVEEQ EIVPVVEQSQ DVVVFTPADL EVVKETAEEV DEFILISAVP KEEVVSQEKE EPQVEQEPTL VVKAQREKKA KKFKVKPATC EKPKFLEYKT CVGDLAVVIA KALDEFKEFC IVNAANEHMS HGGGVAKAIA DFCGPDFVEY CADYVKKHGP QQKLVTPSFV KGIQCVNNVV GPRHGDSNLR EKLVAAYKSV LVGGVVNYVV PVLSSGIFGV DFKISIDAMR EAFKGCAIRV LLFSLSQEHI DYFDATCKQK TIYLTEDGVK YRSVVLKPGD SLGQFGQVFA RNKVVFSADD VEDKEILFIP TTDKTILEYY GLDAQKYVTY LQTLAQKWDV QYRDNFVILE WRDGNCWISS AIVLLQAAKI RFKGFLAEAW AKLLGGDPTD FVAWCYASCN AKVGDFSDAN WLLANLAEHF DADYTNALLK KCVSCNCGVK SYELRGLEAC IQPVRAPNLL HFKTQYSNCP TCGASSTDEV IEASLPYLLL FATDGPATVD CDENAVGTVV FIGSTNSGHC YTQADGKAFD NLAKDRKFGR KSPYITAMYT RFSLRSENPL LVVEHSKGKA KVVKEDVSNL ATSSKASFDD LTDFEQWYDS NIYESLKVQE TPDNLDEYVS FTTKEDSKLP LTLKVRGIKS VVDFRSKDGF TYKLTPDTDE NSKTPVYYPV LDSISLRAIW VEGSANFVVG HPNYYSKSLR IPTFWENAES FVKMGYKIDG VTMGLWRAEH LNKPNLERIF NIAKKAIVGS SVVTTQCGKI LVKAATYVAD KVGDGVVRNI TDRIKGLCGF TRGHFEKKMS LQFLKTLVFF FFYFLKASSK SLVSSYKIVL CKVVFATLLI VWFIYTSNPV VFTGIRVLDF LFEGSLCGPY NDYGKDSFDV LRYCAGDFTC RVCLHDRDSL HLYKHAYSVE QIYKDAASGI NFNWNWLYLV FLILFVKPVA GFVIICYCVK YLVLSSTVLQ TGVGFLDWFV KTVFTHFNFM GAGFYFWLFY KIYVQVHHIL YCKDVTCEVC KRVARSNRQE VSVVVGGRKQ IVHVYTNSGY NFCKRHNWYC RNCDDYGHQN TFMSPEVAGE LSEKLKRHVK PTAYAYHVVY EACVVDDFVN LKYKAAIPGK DNASSAVKCF SVTDFLKKAV FLKEALKCEQ ISNDGFIVCN TQSAHALEEA KNAAVYYAQY LCKPILILDQ ALYEQLIVEP VSKSVIDKVC SILSNIISVD TAALNYKAGT LRDALLSITK DEEAVDMAIF CHNHEVEYTG DGFTNVIPSY GMDTDKLTPR DRGFLINADA SIANLRVKNA PPVVWKFSDL IKLSDSCLKY LISATVKSGG RFFITKSGAK QVISCHTQKL LVEKKAGGVI NNTFKWFMSC FKWLFVFYIL FTACCLGYYY MEMNKSFVHP MYDVNSTLHV EGFKVIDKGV IREIVSEDNC FSNKFVNFDA FWGKSYENNK NCPIVTVVID GDGTVAVGVP GFVSWVMDGV MFVHMTQTDR RPWYIPTWFN REIVGYTQDS IITEGSFYTS IALFSARCLY LTASNTPQLY CFNGDNDAPG ALPFGSIIPH RVYFQPNGVR LIVPQQILHT PYIVKFVSDS YCRGSVCEYT KPGYCVSLDS QWVLFNDEYI SKPGVFCGST VRELMFNMVS TFFTGVNPNI YIQLATMFLI LVVIVLIFAM VIKFQGVFKA YATIVFTIML VWVINAFVLC VHSYNSVLAV ILLVLYCYAS MVTSRNTAII MHCWLVFTFG LIVPTWLACC YLGFILYMYT PLVFWCYGTT KNTRKLYDGN EFVGNYDLAA KSTFVIRGTE FVKLTNEIGD KFEAYLSAYA RLKYYSGTGS EQDYLQACRA WLAYALDQYR NSGVEVVYTP PRYSIGVSRL QAGFKKLVSP SSAVEKCIVS VSYRGNNLNG LWLGDSIYCP RHVLGKFSGD QWGDVLNLAN NHEFEVVTQN GVTLNVVSRR LKGAVLILQT AVANAETPKY KFVKANCGDS FTIACSYGGT VIGLYPVTMR SNGTIRASFL AGACGSVGFN IEKGVVNFFY MHHLELPNAL HTGTDLMGEF YGGYVDEEVA QRVPPDNLVT NNIVAWLYAA IISVKESSFS QPKWLESTTV SIEDYNRWAS DNGFTPFSTS TAITKLSAIT GVDVCKLLRT IMVKSAQWGS DPILGQYNFE DELTPESVFN QVGGVRLQSS FVRKATSWFW SRCVLACFLF VLCAIVLFTA VPLKFYVHAA VILLMAVLFI SFTVKHVMAY MDTFLLPTLI TVIIGVCAEV PFIYNTLISQ VVIFLSQWYD PVVFDTMVPW MLLPLVLYTA FKCVQGCYMN SFNTSLLMLY QFMKLGFVIY TSSNTLTAYT EGNWELFFEL VHTIVLANVS SNSLIGLIVF KCAKWMLYYC NATYFNNYVL MAVMVNGIGW LCTCYFGLYW WVNKVFGLTL GKYNFKVSVD QYRYMCLHKV NPPKTVWEVF TTNILIQGIG GDRVLPIATV QSKLSDVKCT TVVLMQLLTK LNVEANSKMH AYLVELHNKI LASDDVGECM DNLLGMLITL FCIDSTIDLG EYCDDILKRS TVLQSVTQEF SHIPSYAEYE RAKSIYEKVL ADSKNGGVTQ QELAAYRKAA NIAKSVFDRD LAVQKKLDSM AERAMTTMYK EARVTDRRAK LVSSLHALLF SMLKKIDSEK LNVLFDQANS GVVPLATVPI VCSNKLTLVI PDPETWVKCV EGVHVTYSTV VWNIDCVTDA DGTELHPTST GSGLTYCISG DNIAWPLKVN LTRNGHNKVD VALQNNELMP HGVKTKACVA GVDQAHCSVE SKCYYTSISG SSVVAAITSS NPNLKVASFL NEAGNQIYVD LDPPCKFGMK VGDKVEVVYL YFIKNTRSIV RGMVLGAISN VVVLQSKGHE TEEVDAVGIL SLCSFAVDPA DTYCKYVAAG NQPLGNCVKM LTVHNGSGFA ITSKPSPTPD QDSYGGASVC LYCRAHIAHP GGAGNLDGRC QFKGSFVQIP TTEKDPVGFC LRNKVCTVCQ CWIGYGCQCD SLRQPKPSVQ SVAVASGFDK NYLNRVRGSS EARLIPLANG CDPDVVKRAF DVCNKESAGM FQNLKRNCAR FQEVRDTEDG NLEYCDSYFV VKQTTPSNYE HEKACYEDLK SEVTADHDFF VFNKNIYNIS RQRLTKYTMM DFCYALRHFD PKDCEVLKEI LVTYGCIEDY HPKWFEENKD WYDPIENPKY YAMLAKMGPI VRRALLNAIE FGNLMVEKGY VGVITLDNQD LNGKFYDFGD FQKTAPGAGV PVFDTYYSYM MPIIAMTDAL APERYFEYDV HKGYKSYDLL KYDYTEEKQD LFQKYFKYWD QEYHPNCRDC SDDRCLIHCA NFNILFSTLV PQTSFGNLCR KVFVDGVPFI ATCGYHSKEL GVIMNQDNTM SFSKMGLSQL MQFVGDPALL VGTSNKLVDL RTSCFSVCAL ASGITHQTVK PGHFNKDFYD FAEKAGMFKE GSSIPLKHFF YPQTGNAAIN DYDYYRYNRP TMFDIRQLLF CLEVTSKYFE CYEGGCIPAS QVVVNNLDKS AGYPFNKFGK ARLYYEMSLE EQDQLFESTK KNVLPTITQM NLKYAISAKN RARTVAGVSI LSTMTNRQFH QKILKSIVNT RNAPVVIGTT KFYGGWDNML RNLIQGVEDP ILMGWDYPKC DRAMPNLLRI AASLVLARKH TNCCTWSERV YRLYNECAQV LSETVLATGG IYVKPGGTSS GDATTAYANS VFNIIQATSA NVARLLSVIT RDIVYDDIKS LQYELYQQVY RRVNFDPAFV EKFYSYLCKN FSLMILSDDG VVCYNNTLAK QGLVADISGF REVLYYQNNV FMADSKCWVE PDLEKGPHEF CSQHTMLVEV DGEPRYLPYP DPSRILCACV FVDDLDKTES VAVMERYIAL AIDAYPLVHH ENEEYKKVFF VLLSYIRKLY QELSQNMLMD YSFVMDIDKG SKFWEQEFYE NMYRAPTTLQ SCGVCVVCNS QTILRCGNCI RKPFLCCKCC YDHVMHTDHK NVLSINPYIC SQPGCGEADV TKLYLGGMSY FCGNHKPKLS IPLVSNGTVF GIYRANCAGS ENVDDFNQLA TTNWSTVEPY ILANRCVDSL RRFAAETVKA TEELHKQQFA SAEVREVLSD RELILSWEPG KTRPPLNRNY VFTGFHFTRT SKVQLGDFTF EKGEGKDVVY YRATSTAKLS VGDIFVLTSH NVVSLIAPTL CPQQTFSRFV NLRPNVMVPA CFVNNIPLYH LVGKQKRTTV QGPPGSGKSH FAIGLAAYFS NARVVFTACS HAAVDALCEK AFKFLKVDDC TRIVPQRTTI DCFSKFKAND TGKKYIFSTI NALPEVSCDI LLVDEVSMLT NYELSFINGK INYQYVVYVG DPAQLPAPRT LLNGSLSPKD YNVVTNLMVC VKPDIFLAKC YRCPKEIVDT VSTLVYDGKF IANNPESRQC FKVIVNNGNS DVGHESGSAY NITQLEFVKD FVCRNKEWRE ATFISPYNAM NQRAYRMLGL NVQTVDSSQG SEYDYVIFCV TADSQHALNI NRFNVALTRA KRGILVVMRQ RDELYSALKF IELDSVASLQ GTGLFKICNK EFSGVHPAYA VTTKALAATY KVNDELAALV NVEAGSEITY KHLISLLGFK MSVNVEGCHN MFITRDEAIR NVRGWVGFDV EATHACGTNI GTNLPFQVGF STGADFVVTP EGLVDTSIGN NFEPVNSKAP PGEQFNHLRA LFKSAKPWHV VRPRIVQMLA DNLCNVSDCV VFVTWCHGLE LTTLRYFVKI GKDQVCSCGS RATTFNSHTQ AYACWKHCLG FDFVYNPLLV DIQQWGYSGN LQFNHDLHCN VHGHAHVASA DAIMTRCLAI NNAFCQDVNW DLTYPHIANE DEVNSSCRYL QRMYLNACVD ALKVNVVYDI GNPKGIKCVR RGDLNFRFYD KNPIVPNVKQ FEYDYNQHKD KFADGLCMFW NCNVDCYPDN SLVCRYDTRN LSVFNLPGCN GGSLYVNKHA FHTPKFDRTS FRNLKAMPFF FYDSSPCETI QLDGVAQDLV SLATKDCITK CNIGGAVCKK HAQMYADFVT SYNAAVTAGF TFWVTNNFNP YNLWKSFSAL QSIDNIAYNM YKGGHYDAIA GEMPTIVTGD KVFVIDQGVE KAVFFNQTIL PTSVAFELYA KRNIRTLPNN RILKGLGVDV TNGFVIWDYT NQTPLYRNTV KVCAYTDIEP NGLIVLYDDR YGDYQSFLAA DNAVLVSTQC YKRYSYVEIP SNLLVQNGIP LKDGANLYVY KRVNGAFVTL PNTLNTQGRS YETFEPRSDV ERDFLDMSEE SFVEKYGKEL GLQHILYGEV DKPQLGGLHT VIGMCRLLRA NKLNAKSVTN SDSDVMQNYF VLADNGSYKQ VCTVVDLLLD DFLELLRNIL KEYGTNKSKV VTVSIDYHSI NFMAWFEDGI IKTCYPQLQS AWTCGYNMPE LYKVQNCVME PCNIPNYGVG IALPSGIMMN VAKYTQLCQY LSKTTMCVPH NMRVMHFGAG SDKGVAPGST VLKQWLPEGT LLVDNDIVDY VSDAHVSVLS DCNKYKTEHK FDLVISDMYT DNDSKRKHEG VIANNGNDDV FIYLSSFLRN NLALGGSFAV KVTETSWHEV LYDIAQDCAW WTMFCTAVNA SSSEAFLVGV NYLGASEKVK VSGKTLHANY IFWRNCNYLQ TSAYSIFDVA KFDLRLKATP VVNLKTEQKT DLVFNLIKCG KLLVRDVGNT SFTSDSFVCT M
  Domain only
  Domain in chain
  Domain in PDB