Uniprot accession / id : A2AGL3  OR   Uniprot accession / id : Q15413
 
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Entry Information
Entry status  (1)
REL
(5)
 
Experimental methods  (1)
X-ray diffraction
(5)
 
Authors  (8)
Jedrzejczak R
(4)
Joachimiak A
(4)
Midwest Center for Structural Genomics (MCSG)
(4)
Wu R
(4)
Kim Y
(3)
Lau K
(1)
Van Petegem F
(1)
Yuchi Z
(1)
 
Homo / hetero assembly  (1)
homo
(5)
 
Assembly composition  (1)
protein structure
(5)
 
Assembly polymer count  (1)
monomer
(5)
 
Resolution distribution
1.5 - 2
(1)
2.5 - 3
(3)
3.0 - 3.5
(1)
 
Release year distribution
2010 - 2015
(1)
2015 - 2020
(4)
2020 - 2025
(4)
 
Journal  (2)
To be published
(4)
Structure
(1)
 
Macromolecules
Organism superkingdom  (1)
Eukaryota
(5)
 
Organism name  (1)
Homo sapiens
(5)
 
Molecule name  (6)
Brain ryanodine receptor-calcium release channel
(5)
Brain-type ryanodine receptor
(5)
RYR-3
(5)
RyR3
(5)
Ryanodine receptor 3
(5)
Type 3 ryanodine receptor
(5)
 
Molecule type  (1)
Protein
(5)
 
Gene names  (2)
HBRR
(5)
RYR3
(5)
 
Interacting ligands  (6)
GOL : GLYCEROL
(3)
ATP : ADENOSINE-5'-TRIPHOSPHATE
(1)
PEG : DI(HYDROXYETHYL)ETHER
(1)
PO4 : PHOSPHATE ION
(1)
SO4 : SULFATE ION
(1)
TRS : 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
(1)
 
Function and Biology
Biological function  (1)
ryanodine-sensitive calcium-release channel activity
(4)
 
Biological process  (1)
calcium ion transport
(5)
 
Sequence and Structure classification
CATH class  (1)
Mainly Alpha
(1)
 
CATH topology  (1)
Globin-like
(1)
 
Pfam accession / name  (1)
PF02026 : RyR
(5)
 
Experimental Information
Diffraction protocol  (1)
Single wavelength
(5)
 
Diffraction radiation source type  (1)
Synchrotron
(5)
 
Diffraction source  (2)
APS BEAMLINE 19-ID
(4)
CLSI BEAMLINE 08ID-1
(1)
 
Synchrotron site  (2)
APS
(4)
CLSI
(1)
 
Diffraction detector type  (2)
CCD
(4)
Pixel
(1)
 
Refinement software  (2)
PHENIX
(4)
REFMAC
(1)
 
Representative Structures
Representative Structures
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Entries 1 to 5 of 5
Entries 1 to 5 of 5
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Crystal Structure of Human RYR Receptor 3 (848-1055)
Wu R, Joachimiak A, Jedrzejczak R, Midwest Center for Structural Genomics (MCSG)
To be published
Source organism: Homo sapiens  
Assembly composition: protein only structure
Bound ligands: GOL    PO4   
Modified residues: MSE    MSE   
Assembly name: Ryanodine receptor 3 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-172280 (Preferred)   search this ID
PDBe-KB: Q15413   
X-ray diffraction
2.504Å resolution
Released: 5 Aug 2020
Model geometry
Fit model/data
6uhb
6uhb
6uhb
Crystal Structure of Human RYR Receptor 3 ( 848-1055) in Complex with ATP
Wu R, Kim Y, Jedrzejczak R, Joachimiak A, Midwest Center for Structural Genomics (MCSG)
To be published
Source organism: Homo sapiens  
Assembly composition: protein only structure
Bound ligands: PEG    GOL    PEG    TRS    ATP    ATP    TRS   
Modified residues: MSE    MSE   
Assembly name: Ryanodine receptor 3 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-172280 (Preferred)   search this ID
PDBe-KB: Q15413   
X-ray diffraction
3.138Å resolution
Released: 5 Aug 2020
Model geometry
Fit model/data
6uhh
6uhh
6uhh
Closed-form Crystal Structure of Human RYR Receptor 3 ( 848-1055)
Wu R, Kim Y, Jedrzejczak R, Joachimiak A, Midwest Center for Structural Genomics (MCSG)
To be published
Source organism: Homo sapiens  
Assembly composition: protein only structure
Assembly name: Ryanodine receptor 3 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-172280 (Preferred)   search this ID
PDBe-KB: Q15413   
X-ray diffraction
2.892Å resolution
Released: 5 Aug 2020
Model geometry
Fit model/data
6uhe
6uhe
6uhe
Open-form Crystal Structure of Human RYR Receptor 3 ( 848-1055)
Wu R, Kim Y, Jedrzejczak R, Joachimiak A, Midwest Center for Structural Genomics (MCSG)
To be published
Source organism: Homo sapiens  
Assembly composition: protein only structure
Bound ligands: PEG    PEG   
Modified residues: MSE    MSE   
Assembly name: Ryanodine receptor 3 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-172280 (Preferred)   search this ID
PDBe-KB: Q15413   
X-ray diffraction
2.855Å resolution
Released: 5 Aug 2020
Model geometry
Fit model/data
6uha
6uha
6uha
Crystal structure of human ryanodine receptor 3 (2597-2800)
Yuchi Z, Lau K, Van Petegem F
Structure (2012) [PMID: 22705209  ]
Source organism: Homo sapiens  
Assembly composition: protein only structure
Bound ligands: GOL    SO4   
Assembly name: Ryanodine receptor 3 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-172280 (Preferred)   search this ID
PDBe-KB: Q15413   
X-ray diffraction
1.75Å resolution
Released: 13 Jun 2012
Model geometry
Fit model/data
4erv
4erv
4erv
Entries 1 to 5 of 5
Entries 1 to 5 of 5