Entry status  (1)

REL

(5)

Experimental methods  (3)

Solution NMR

(2)

X-ray diffraction

(2)

Electron Microscopy

(1)

Authors  (38)

Pitt GS

(2)

Wang C

(2)

Andresen CNJ

(1)

Arbing MA

(1)

Bennett V

(1)

Chen K

(1)

Chung BC

(1)

Gao S

(1)

Hovey L

(1)

Huang G

(1)

Huang X

(1)

Hunt JF

(1)

Isbell HM

(1)

Kilpatrick AM

(1)

Kim EH

(1)

Lee SY

(1)

Lei J

(1)

Levine JA

(1)

Li S

(1)

Li Z

(1)

Liu L

(1)

Mahling R

(1)

Marx DC

(1)

Miller MS

(1)

Miloushev VZ

(1)

Palmer AG

(1)

Pan X

(1)

Shea MA

(1)

Shen H

(1)

Wang HG

(1)

Weaver LD

(1)

Wei Z

(1)

Yan H

(1)

Yan N

(1)

Ye F

(1)

Yoder JB

(1)

Yu C

(1)

Zhang M

(1)

Homo / hetero assembly  (2)

hetero

(3)

homo

(2)

Assembly composition  (2)

protein/protein complex

(3)

protein structure

(2)

Assembly polymer count  (3)

monomer

(2)

trimer

(2)

dimer

(1)

Resolution distribution

2.5 - 3

(2)

3.0 - 3.5

(1)

Release year distribution

2005 - 2010

(1)

2010 - 2015

(2)

2015 - 2020

(2)

Journal  (5)

Elife

(1)

J Biol Chem

(1)

Nat Commun

(1)

Science

(1)

Structure

(1)

Organism superkingdom  (1)

Eukaryota

(5)

Organism name  (2)

Homo sapiens

(5)

Mus musculus

(1)

Molecule name  (10)

HBSC II

(5)

Sodium channel protein brain II subunit alpha

(5)

Sodium channel protein type 2 subunit alpha

(5)

Sodium channel protein type II subunit alpha

(5)

Voltage-gated sodium channel subunit alpha Nav1.2

(5)

ANK-2

(1)

Ankyrin-2

(1)

Ankyrin-B

(1)

Brain ankyrin

(1)

Non-erythroid ankyrin

(1)

Molecule type  (1)

Protein

(5)

Gene names  (7)

HBA

(5)

NAC2

(5)

SCN2A

(5)

SCN2A1

(5)

SCN2A2

(5)

ANK2

(1)

ANKB

(1)

Interacting Molecules  (4)

Calmodulin-1

(2)

Fibroblast growth factor 13

(1)

Mu-conotoxin KIIIA

(1)

Sodium channel regulatory subunit beta-2

(1)

Interacting ligands  (5)

9Z9 : (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en

(1)

BMA : beta-D-mannopyranose

(1)

NA : SODIUM ION

(1)

NAG : 2-acetamido-2-deoxy-beta-D-glucopyranose

(1)

SO4 : SULFATE ION

(1)

Biological function  (6)

monoatomic cation channel activity

(3)

calmodulin binding

(1)

monoatomic ion channel activity

(1)

protein binding

(1)

sodium channel activity

(1)

voltage-gated sodium channel activity

(1)

Biological process  (14)

action potential

(1)

cardiac muscle cell action potential involved in contraction

(1)

cellular response to hypoxia

(1)

intrinsic apoptotic signaling pathway in response to osmotic stress

(1)

memory

(1)

monoatomic ion transmembrane transport

(1)

monoatomic ion transport

(1)

myelination

(1)

nervous system development

(1)

neuron apoptotic process

(1)

neuronal action potential

(1)

sodium ion transmembrane transport

(1)

sodium ion transport

(1)

transmembrane transport

(1)

Biological cell component  (6)

plasma membrane

(3)

axon

(1)

membrane

(1)

monoatomic ion channel complex

(1)

node of Ranvier

(1)

voltage-gated sodium channel complex

(1)

CATH class  (1)

Mainly Alpha

(3)

CATH topology  (3)

Recoverin; domain 1

(2)

Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat

(1)

Single alpha-helices involved in coiled-coils or other helix-helix interfaces

(1)

Pfam accession / name  (4)

PF00023 : Ank

(1)

PF00520 : Ion_trans

(1)

PF06512 : Na_trans_assoc

(1)

PF11933 : Na_trans_cytopl

(1)

Diffraction protocol  (1)

Single wavelength

(2)

Diffraction radiation source type  (1)

Synchrotron

(2)

Diffraction source  (2)

APS BEAMLINE 24-ID-C

(1)

SSRF BEAMLINE BL17U

(1)

Synchrotron site  (2)

APS

(1)

SSRF

(1)

Diffraction detector type  (1)

CCD

(2)

Refinement software  (1)

PHENIX

(2)

EM microscope model  (1)

FEI TITAN KRIOS

(1)

EM detector name  (1)

GATAN K2 QUANTUM (4k x 4k)

(1)

NMR software packages  (10)

NMRPipe

(2)

ARIA

(1)

Amber

(1)

CNS

(1)

CYANA

(1)

CcpNmr Analysis

(1)

Sparky

(1)

TopSpin

(1)

VNMR

(1)

Xplor-NIH

(1)

NMR Field Strength

400.0 - 500

(1)

500.0 - 600

(2)

600.0 - 700

(2)

700.0 - 800

(2)

800.0 - 900

(2)

Representative Structures

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