Uniprot accession / id : (O00182)
 
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Entry Information
Entry status  (1)
REL
(15)
 
Experimental methods  (1)
X-ray diffraction
(15)
 
Authors  (60)
Nakamura T
(11)
Nishi N
(11)
Kato R
(8)
Wakatsuki S
(7)
Nagae M
(6)
Hirashima M
(5)
Kamitori S
(5)
Yoshida H
(5)
Murata T
(4)
Nakakita S
(4)
Teraoka M
(4)
Usui T
(4)
Andre S
(2)
André S
(2)
Buzamet E
(2)
Canada FJ
(2)
Cañada FJ
(2)
Gabius HJ
(2)
Haroske G
(2)
Hirabayashi J
(2)
Jimenez-Barbero J
(2)
Jiménez-Barbero J
(2)
Kaltner H
(2)
Kloor M
(2)
Kopitz J
(2)
Lensch M
(2)
Lohr M
(2)
Lopez-Merino L
(2)
López-Merino L
(2)
Mate MJ
(2)
Maté MJ
(2)
Menendez M
(2)
Menéndez M
(2)
Nakamura-Tsuruta S
(2)
Ribeiro JP
(2)
Romero A
(2)
Ruiz FM
(2)
Saiz JL
(2)
Solis D
(2)
Solís D
(2)
Sáiz JL
(2)
Wollina U
(2)
Ando H
(1)
Imamura A
(1)
Ishida H
(1)
Kishishita S
(1)
Kiso M
(1)
Komura N
(1)
Kuwabara N
(1)
Makyio H
(1)
Menjo M
(1)
Murayama K
(1)
Nishino A
(1)
RIKEN Structural Genomics/Proteomics Initiative (RSGI)
(1)
Shirouzu M
(1)
Suzuki T
(1)
Terada T
(1)
Wada K
(1)
Yamada Y
(1)
Yokoyama S
(1)
 
Homo / hetero assembly  (1)
homo
(15)
 
Assembly composition  (1)
protein structure
(15)
 
Assembly polymer count  (2)
monomer
(14)
trimer
(1)
 
Resolution distribution
1.0 - 1.5
(3)
1.5 - 2
(8)
2.0 - 2.5
(3)
2.5 - 3
(1)
 
Release year distribution
2005 - 2010
(13)
2010 - 2015
(8)
2015 - 2020
(1)
 
Journal  (7)
Glycobiology
(4)
J Biol Chem
(4)
Int J Biochem Cell Biol
(2)
J Mol Biol
(2)
Biochem Biophys Res Commun
(1)
Bioorg Med Chem
(1)
To be published
(1)
 
Macromolecules
Organism superkingdom  (1)
Eukaryota
(15)
 
Organism name  (1)
Homo sapiens
(15)
 
Molecule name  (4)
Ecalectin
(15)
Gal-9
(15)
Galectin-9
(15)
Tumor antigen HOM-HD-21
(15)
 
Molecule type  (1)
Protein
(15)
 
Gene names  (1)
LGALS9
(15)
 
Interacting ligands  (18)
GAL : beta-D-galactopyranose
(12)
NAG : 2-acetamido-2-deoxy-beta-D-glucopyranose
(5)
NI : NICKEL (II) ION
(4)
BGC : beta-D-glucopyranose
(3)
GLC : alpha-D-glucopyranose
(2)
NDG : 2-acetamido-2-deoxy-alpha-D-glucopyranose
(2)
PRD_900004 : beta-lactose
(2)
PRD_900008 : alpha-lactose
(2)
PRD_900019 : N-acetyl-alpha-lactosamine
(2)
A2G : 2-acetamido-2-deoxy-alpha-D-galactopyranose
(1)
DTV : (2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL
(1)
EDO : 1,2-ETHANEDIOL
(1)
GOL : GLYCEROL
(1)
LSE : 2-(trimethylsilyl)ethyl 4-O-beta-D-galactopyranosyl-6-Se-methyl-6-seleno-beta-D-glucopyranoside
(1)
MAN : alpha-D-mannopyranose
(1)
NGA : 2-acetamido-2-deoxy-beta-D-galactopyranose
(1)
SIA : N-acetyl-alpha-neuraminic acid
(1)
ZN : ZINC ION
(1)
 
Function and Biology
Biological function  (1)
carbohydrate binding
(15)
 
Sequence and Structure classification
CATH class  (1)
Mainly Beta
(15)
 
CATH topology  (1)
Jelly Rolls
(15)
 
Pfam accession / name  (1)
PF00337 : Gal-bind_lectin
(15)
 
Experimental Information
Diffraction protocol  (1)
Single wavelength
(15)
 
Diffraction radiation source type  (1)
Synchrotron
(15)
 
Diffraction source  (6)
PHOTON FACTORY BEAMLINE AR-NW12A
(6)
PHOTON FACTORY BEAMLINE BL-5A
(4)
ESRF BEAMLINE BM16
(2)
PHOTON FACTORY BEAMLINE AR-NE3A
(1)
PHOTON FACTORY BEAMLINE BL-17A
(1)
SPRING-8 BEAMLINE BL26B2
(1)
 
Synchrotron site  (3)
Photon Factory
(12)
ESRF
(2)
SPring-8
(1)
 
Diffraction detector type  (1)
CCD
(15)
 
Refinement software  (2)
REFMAC
(9)
CNS
(6)
 
Representative Structures
Representative Structures
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Entries 1 to 10 of 15
Entries 1 to 10 of 15
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Crystal Structure of a protease-resistant mutant form of human galectin-9
Yoshida H, Kamitori S
Biochem Biophys Res Commun (2017) [PMID: 28687490  ]
Source organism: Homo sapiens  
Assembly composition: protein only structure
Bound ligands: ZN    ZN    EDO   
Carbohydrate polymer components:
Molecule 1 - BGC(1), GAL(1)
Molecule 2 - GAL(1), GLC(1)
Assembly name: Galectin-9 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-126137 (Preferred)   search this ID
PDBe-KB: O00182    O00182   
X-ray diffraction
1.95Å resolution
Released: 20 May 2015
Model geometry
Fit model/data
3wv6
3wv6
3wv6
N-Domain of human adhesion/growth-regulatory galectin-9
Ruiz FM, Romero A
Int J Biochem Cell Biol (2010) [PMID: 20227520  ]
Source organism: Homo sapiens  
Assembly composition: protein only structure
Assembly name: Galectin-9 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-126137 (Preferred)   search this ID
PDBe-KB: O00182   
X-ray diffraction
2.03Å resolution
Released: 5 May 2010
Model geometry
Fit model/data
3lsd
3lsd
3lsd
Crystal Structure of human galectin-9 NCRD with Selenolactose
Makyio H, Suzuki T, Ando H, Yamada Y, Ishida H, Kiso M, Wakatsuki S, Kato R
Bioorg Med Chem (2014) [PMID: 24631362  ]
Source organism: Homo sapiens  
Assembly composition: protein only structure
Bound ligands: LSE    LSE   
Assembly name: Galectin-9 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-126137 (Preferred)   search this ID
PDBe-KB: O00182   
X-ray diffraction
1.4Å resolution
Released: 5 Nov 2014
Model geometry
Fit model/data
3wlu
3wlu
3wlu
Crystal structure of human galectin-9 C-terminal CRD
Yoshida H, Kamitori S
J Biol Chem (2010) [PMID: 20861009  ]
Source organism: Homo sapiens  
Assembly composition: protein only structure
Bound ligands: NI    NI   
Assembly name: Galectin-9 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-126137 (Preferred)   search this ID
PDBe-KB: O00182   
X-ray diffraction
1.5Å resolution
Released: 22 Sep 2010
Model geometry
Fit model/data
3nv1
3nv1
3nv1
Crystal structure of human galectin-9 N-terminal CRD in complex with N-acetyllactosamine dimer (crystal 1)
Nagae M, Nishi N, Murata T, Usui T, Nakamura T, Wakatsuki S, Kato R
Glycobiology (2009) [PMID: 18977853  ]
Source organism: Homo sapiens  
Assembly composition: protein only structure
Carbohydrate polymer components:
Molecule 1 - GAL(2), NAG(2)
Assembly name: Galectin-9 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-126137 (Preferred)   search this ID
PDBe-KB: O00182   
X-ray diffraction
1.8Å resolution
Released: 30 Dec 2008
Model geometry
Fit model/data
2zhk
2zhk
2zhk
Crystal structure of N-terminal domain of human galectin-9 containing L-acetyllactosamine
Kishishita S, Nishino A, Murayama K, Terada T, Shirouzu M, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
To be published
Source organism: Homo sapiens  
Assembly composition: protein only structure
Carbohydrate polymer components:
Molecule 1 - GAL(1), NDG(1)
Assembly name: Galectin-9 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-126137 (Preferred)   search this ID
PDBe-KB: O00182   
X-ray diffraction
2.17Å resolution
Released: 29 Apr 2008
Model geometry
Fit model/data
2yy1
2yy1
2yy1
Crystal structure of human galectin-9 N-terminal CRD in complex with N-acetyllactosamine trimer (crystal 2)
Nagae M, Nishi N, Murata T, Usui T, Nakamura T, Wakatsuki S, Kato R
Glycobiology (2009) [PMID: 18977853  ]
Source organism: Homo sapiens  
Assembly composition: protein only structure
Bound ligands: RPN   
Carbohydrate polymer components:
Molecule 1 - GAL(3), NAG(3)
Assembly name: Galectin-9 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-126137 (Preferred)   search this ID
PDBe-KB: O00182   
X-ray diffraction
1.3Å resolution
Released: 30 Dec 2008
Model geometry
Fit model/data
2zhn
2zhn
2zhn
Crystal structure of human galectin-9 N-terminal CRD in complex with N-acetyllactosamine dimer (crystal 2)
Nagae M, Nishi N, Murata T, Usui T, Nakamura T, Wakatsuki S, Kato R
Glycobiology (2009) [PMID: 18977853  ]
Source organism: Homo sapiens  
Assembly composition: protein only structure
Carbohydrate polymer components:
Molecule 1 - GAL(2), NAG(2)
Assembly name: Galectin-9 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-126137 (Preferred)   search this ID
PDBe-KB: O00182   
X-ray diffraction
1.75Å resolution
Released: 30 Dec 2008
Model geometry
Fit model/data
2zhl
2zhl
2zhl
Crystal structure of human galectin-9 N-terminal CRD in complex with N-acetyllactosamine trimer (crystal 1)
Nagae M, Nishi N, Murata T, Usui T, Nakamura T, Wakatsuki S, Kato R
Glycobiology (2009) [PMID: 18977853  ]
Source organism: Homo sapiens  
Assembly composition: protein only structure
Bound ligands: RPN   
Carbohydrate polymer components:
Molecule 1 - GAL(3), NAG(3)
Molecule 2 - GAL(3), NAG(2)
Molecule 3 - GAL(2), NAG(2)
Assembly name: Galectin-9 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-126137 (Preferred)   search this ID
PDBe-KB: O00182   
X-ray diffraction
1.84Å resolution
Released: 30 Dec 2008
Model geometry
Fit model/data
2zhm
2zhm
2zhm
N-Domain of human adhesion/growth-regulatory galectin-9 in complex with lactose
Ruiz FM, Romero A
Int J Biochem Cell Biol (2010) [PMID: 20227520  ]
Source organism: Homo sapiens  
Assembly composition: protein only structure
Carbohydrate polymer components:
Molecule 1 - BGC(1), GAL(1)
Assembly name: Galectin-9 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-126137 (Preferred)   search this ID
PDBe-KB: O00182   
X-ray diffraction
2.69Å resolution
Released: 5 May 2010
Model geometry
Fit model/data
3lse
3lse
3lse
Entries 1 to 10 of 15
Entries 1 to 10 of 15