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Entry status
(1)
Experimental methods
(2)
Solution NMR
(2)
X-ray diffraction
(2)
Authors
(8)
Barrera-Vilarmau S
(2)
Hinds MG
(2)
Kvansakul M
(2)
Obregon P
(2)
Obregón P
(2)
Suraweera CD
(2)
de Alba E
(2)
Burton DR
(1)
Homo / hetero assembly
(2)
hetero
(2)
homo
(2)
Assembly composition
(2)
protein structure
(2)
protein/protein complex
(2)
Assembly polymer count
(3)
monomer
(2)
dimer
(1)
tetramer
(1)
Resolution distribution
1.5 - 2
(1)
2.0 - 2.5
(1)
Release year distribution
2010 - 2015
(2)
2015 - 2020
(1)
2020 - 2025
(2)
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PLoS One
(2)
FEBS Lett
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(1)
Macromolecules
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(2)
Eukaryota
(3)
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(2)
Organism name
(4)
Homo sapiens
(3)
Orf virus
(1)
Sheeppox virus (strain TU-V02127)
(1)
synthetic construct
(1)
Molecule name
(5)
Activator of apoptosis harakiri
(4)
BH3-interacting domain-containing protein 3
(4)
Neuronal death protein DP5
(4)
Anti-apoptotic membrane protein
(1)
Apoptosis inhibitor
(1)
Molecule type
(1)
Protein
(4)
Gene names
(5)
BID3
(4)
HRK
(4)
ORF125
(1)
ORFV125
(1)
SPPV_14
(1)
Interacting Molecules
(3)
Activator of apoptosis harakiri
(2)
Anti-apoptotic membrane protein
(1)
Apoptosis inhibitor
(1)
Interacting ligands
(2)
EDO : 1,2-ETHANEDIOL
(1)
GOL : GLYCEROL
(1)
Function and Biology
Biological process
(2)
regulation of apoptotic process
(3)
symbiont-mediated suppression of host apoptosis
(1)
Sequence and Structure classification
Pfam accession / name
(2)
PF15196 : Harakiri
(2)
PF11099 : M11L
(1)
Experimental Information
Diffraction protocol
(1)
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(2)
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(1)
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(2)
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(1)
AUSTRALIAN SYNCHROTRON BEAMLINE MX2
(2)
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Australian Synchrotron
(2)
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(6)
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(2)
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(2)
NMR Field Strength
500.0 - 600
(2)
600.0 - 700
(2)
Representative Structures
Representative Structures
Entries
Macromolecules
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Entries 1 to 4 of 4
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ORF virus encoded Bcl-2 homolog ORFV125 in complex with Puma BH3 peptide
Suraweera CD, Hinds MG, Kvansakul M
Viruses
(2021)
[PMID: 34372579 ]
Source organisms: Orf virus , Homo sapiens
Assembly composition: protein/protein complex
Assembly name:
Activator of apoptosis harakiri and Apoptosis inhibitor
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-102672 (Preferred)
search this ID
Structural insight into sheep-pox virus mediated inhibition of apoptosis
Suraweera CD, Hinds MG, Kvansakul M
FEBS Lett
(2020)
[PMID: 32390192 ]
Source organisms: Sheeppox virus (strain TU-V02127) , Homo sapiens
Assembly composition: protein/protein complex
Assembly name:
Activator of apoptosis harakiri and Anti-apoptotic membrane protein
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-104836 (Preferred)
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Solution structure of the transmembrane domain of Bcl-2 member Harakiri in micelles
Barrera-Vilarmau S, Obregon P, de Alba E
PLoS One
(2011)
[PMID: 21731739 ]
Source organism: Homo sapiens
Assembly composition: protein only structure
Assembly name:
Activator of apoptosis harakiri
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-126148 (Preferred)
search this ID
PDBe-KB:
O00198
Solution structure of the cytosolic fragment 22-53 of Bcl-2 member Harakiri
Barrera-Vilarmau S, Obregon P, de Alba E
PLoS One
(2011)
[PMID: 21731739 ]
Source organism: synthetic construct
Assembly composition: protein only structure
Assembly name:
Activator of apoptosis harakiri
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-126148 (Preferred)
search this ID
PDBe-KB:
O00198
Entries 1 to 4 of 4