Uniprot accession / id : O35930  OR   Uniprot accession / id : P07359
 
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Entry status  (1)
REL
(23)
 
Authors  (92)
Celikel R
(4)
Ruggeri ZM
(4)
Varughese KI
(4)
Emsley J
(3)
McClintock RA
(3)
Mendolicchio GL
(3)
Roberts JR
(3)
Shu ZM
(3)
Zhou AW
(3)
Blenner MA
(2)
Dong X
(2)
Dumas JJ
(2)
Freund SM
(2)
Freund SMV
(2)
Gros P
(2)
Huizinga EG
(2)
Huntington JA
(2)
Kumar R
(2)
Lechtenberg BC
(2)
Mosyak L
(2)
Munday AD
(2)
Permi P
(2)
Romijn RA
(2)
Romijn RAP
(2)
Schiphorst ME
(2)
Sixma JJ
(2)
Somers WS
(2)
Springer TA
(2)
Tsuji S
(2)
Ware J
(2)
Ylanne J
(2)
Ylänne J
(2)
de Groot PG
(2)
Andrews RK
(1)
Armstrong C
(1)
Caulton SG
(1)
Clemetson JM
(1)
Clemetson KJ
(1)
Clemetson KJM
(1)
Diacovo TG
(1)
Doggett T
(1)
Duan JS
(1)
Fickling A
(1)
Fukuda K
(1)
Gao YX
(1)
Harrison T
(1)
Hartwig JH
(1)
Heikkinen O
(1)
Jing H
(1)
Ke JY
(1)
Kilpelainen I
(1)
Kilpeläinen I
(1)
Laurenzi IJ
(1)
Li R
(1)
Liang X
(1)
Liddington RC
(1)
Lopez JA
(1)
López JA
(1)
McDonagh T
(1)
McEwan PA
(1)
Mo X
(1)
Moore KL
(1)
Morgan J
(1)
Nakamura F
(1)
Ng R
(1)
Niu LW
(1)
Pentikainen OT
(1)
Pentikainen U
(1)
Pentikäinen OT
(1)
Pentikäinen U
(1)
Pudas R
(1)
Ruskamo S
(1)
Saleem M
(1)
Searle MS
(1)
Seehra J
(1)
Seppala J
(1)
Seppälä J
(1)
Sethi R
(1)
Stahl ML
(1)
Stossel TP
(1)
Sullivan F
(1)
Tao Y
(1)
Tossavainen H
(1)
Uff S
(1)
Wang J
(1)
Williams HEL
(1)
Wong SS
(1)
Ylilauri M
(1)
Zang J
(1)
Zarpellon A
(1)
Zhang X
(1)
Zhu ZL
(1)
 
Homo / hetero assembly  (2)
hetero
(18)
homo
(5)
 
Representative Structures
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Entries 1 to 10 of 23
Entries 1 to 10 of 23
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Cryo-EM structure of GPIb-IX Complex
Shu ZM, Duan JS, Zhou AW
To be published
Source organism: Homo sapiens  
Assembly composition: protein/protein complex
Carbohydrate polymer components:
Molecule 1 - NAG(2)
Molecule 2 - BMA(1), NAG(2)
PDBe complex ID: PDB-CPX-283209 (Preferred)   search this ID
PDBe-KB: P07359    P13224    P14770   
Electron Microscopy
3.36Å resolution
Released: 25 Dec 2024
Model geometry
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Data not analysed
8wfs
8wfs
8wfs
14-3-3 zeta complexed with S609 phosphorylated peptide derived from GPIb alpha cytoplasmic domain
Shu ZM, Zhou AW
To be published
Source organism: Homo sapiens  
Assembly composition: protein/protein complex
Modified residues: SEP    SEP   
Assembly name: Glycocalicin and 14-3-3 protein zeta/delta (Preferred)   search this complex
PDBe complex ID: PDB-CPX-276026 (Preferred)   search this ID
PDBe-KB: P07359    P63104   
X-ray diffraction
2.11Å resolution
Released: 25 Sep 2024
Model geometry
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8we2
8we2
8we2
14-3-3 zeta complexed with S559 phosphorylated peptide derived from GPIb alpha cytoplasmic domain
Shu ZM, Zhou AW
To be published
Source organism: Homo sapiens  
Assembly composition: protein/protein complex
Bound ligands: SIN   
Modified residues: SEP    SEP   
Assembly name: Glycocalicin and 14-3-3 protein zeta/delta (Preferred)   search this complex
PDBe complex ID: PDB-CPX-276026 (Preferred)   search this ID
PDBe-KB: P07359    P63104   
X-ray diffraction
2.47Å resolution
Released: 25 Sep 2024
Model geometry
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8wf6
8wf6
8wf6
The metal ion-dependent adhesion site (MIDAS) of the alphaMbeta2 integrin Mac-1 I-domain promiscuously and competitively binds multiple ligands in the regulation of Leukocyte function
Emsley J, Saleem M
Blood Adv (2019) [PMID: 31053572  ]
Source organism: Mus musculus  
Assembly composition: protein only structure
Bound ligands: IMD    MES    IMD    PEG    GOL    PEG    POL   
Assembly name: Glycocalicin (Preferred)   search this complex
PDBe complex ID: PDB-CPX-128720 (Preferred)   search this ID
PDBe-KB: O35930   
X-ray diffraction
2Å resolution
Released: 24 Oct 2018
Model geometry
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6ejx
6ejx
6ejx
Structure of a novel antithrombotic agent Agkisacucetin in complex with the platelet glycoprotein Ib receptor
Wang J, Gao YX, Ke JY, Zhu ZL, Niu LW
To be published
Assembly composition: protein/protein complex
PDBe complex ID: PDB-CPX-139564 (Preferred)   search this ID
PDBe-KB: P07359    Q8JIV9    Q8AYA3   
X-ray diffraction
3.3Å resolution
Released: 23 Jun 2021
Model geometry
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6xfq
6xfq
6xfq
Crystal Structure of High-Affinity von Willebrand Factor A1 domain with Disulfide Mutation in Complex with High Affinity GPIb alpha
Blenner MA, Dong X, Springer TA
J Biol Chem (2014) [PMID: 24391089  ]
Source organism: Homo sapiens  
Assembly composition: protein/protein complex
Bound ligands: MES    PEG    PEG    SO4   
Assembly name: Glycocalicin and von Willebrand factor (Preferred)   search this complex
PDBe complex ID: PDB-CPX-137564 (Preferred)   search this ID
PDBe-KB: P07359    P04275   
X-ray diffraction
2.8Å resolution
Released: 8 Jan 2014
Model geometry
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4c2b
4c2b
4c2b
Crystal Structure of the Complex of Platelet Receptor GPIb-alpha and Human alpha-Thrombin
Varughese KI, Celikel R, Ruggeri ZM
Science (2003) [PMID: 12855810  ]
Source organisms: Synthetic construct, Homo sapiens  
Assembly composition: protein/protein complex
Bound ligands: NAG    CL    NAG   
Modified residues: TYS    TYS   
Carbohydrate polymer components:
Molecule 1 - MAN(3), NAG(2)
Assembly name: alpha-thrombin complex and Glycocalicin (Preferred)   search this complex
PDBe complex ID: PDB-CPX-133074 (Preferred)   search this ID
PDBe-KB: P07359    P00734   
X-ray diffraction
2.3Å resolution
Released: 22 Jul 2003
Model geometry
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1ook
1ook
1ook
Crystal Structure of N-Terminal Domain of Human Platelet Receptor Glycoprotein Ib-alpha at 2.8 Angstrom Resolution
Varughese KI, Ruggeri ZM, Celikel R
Acta Crystallogr D Biol Crystallogr (2004) [PMID: 14993663  ]
Source organism: Homo sapiens  
Assembly composition: protein only structure
Bound ligands: NAG    PT    NAG    PT   
Carbohydrate polymer components:
Molecule 1 - MAN(2), NAG(2)
Assembly name: Glycocalicin (Preferred)   search this complex
PDBe complex ID: PDB-CPX-139560 (Preferred)   search this ID
PDBe-KB: P07359   
X-ray diffraction
2.8Å resolution
Released: 2 Mar 2004
Model geometry
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1qyy
1qyy
1qyy
Crystal structure of Filamin A domain 17 and GPIb alpha cytoplasmic domain complex
Pudas R, Ylanne J
Blood (2006) [PMID: 16293600  ]
Source organism: Homo sapiens  
Assembly composition: protein/protein complex
Bound ligands: GOL   
Assembly name: Glycocalicin and Filamin-A (Preferred)   search this complex
PDBe complex ID: PDB-CPX-139561 (Preferred)   search this ID
PDBe-KB: P07359    P21333   
X-ray diffraction
2.32Å resolution
Released: 30 Nov 2005
Model geometry
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Data not analysed
2bp3
2bp3
2bp3
Crystal Structure of the von Willebrand Factor Binding Domain of Glycoprotein Ib alpha
Huizinga EG, Tsuji S, Romijn RAP, Schiphorst ME, de Groot PG, Sixma JJ, Gros P
Science (2002) [PMID: 12183630  ]
Source organism: Homo sapiens  
Assembly composition: protein only structure
Assembly name: Glycocalicin (Preferred)   search this complex
PDBe complex ID: PDB-CPX-139560 (Preferred)   search this ID
PDBe-KB: P07359   
X-ray diffraction
1.85Å resolution
Released: 28 Aug 2002
Model geometry
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1m0z
1m0z
1m0z
Entries 1 to 10 of 23
Entries 1 to 10 of 23