Entry status  (1)

REL

(4)

Experimental methods  (2)

Solution NMR

(3)

X-ray diffraction

(1)

Authors  (27)

Nagata S

(2)

Otomo T

(2)

Sakahira H

(2)

Uegaki K

(2)

Yamazaki T

(2)

Han W-D

(1)

Han WD

(1)

Kim M-S

(1)

Kim MS

(1)

Kim Y-G

(1)

Kim YG

(1)

Kyogoku Y

(1)

Li P

(1)

Lugovskoy AA

(1)

McCarty JS

(1)

Oh B-H

(1)

Oh BH

(1)

Park S-Y

(1)

Park SY

(1)

Robinson H

(1)

Shimizu M

(1)

Shin S

(1)

Wagner G

(1)

Woo E-J

(1)

Woo EJ

(1)

Yumoto N

(1)

Zhou P

(1)

Homo / hetero assembly  (2)

hetero

(2)

homo

(2)

Assembly composition  (2)

protein structure

(2)

protein/protein complex

(2)

Assembly polymer count  (2)

dimer

(3)

monomer

(1)

Resolution distribution

2.5 - 3

(1)

Release year distribution

1995 - 2000

(2)

2000 - 2005

(4)

Journal  (4)

J Mol Biol

(1)

Mol Cell

(1)

Nat Struct Biol

(1)

Proc Natl Acad Sci U S A

(1)

Organism superkingdom  (1)

Eukaryota

(4)

Organism name  (2)

Mus musculus

(3)

Homo sapiens

(1)

Molecule name  (8)

CAD

(4)

Caspase-activated DNase

(4)

Caspase-activated deoxyribonuclease

(4)

DFF-40

(4)

DNA fragmentation factor 40 kDa subunit

(4)

DNA fragmentation factor subunit beta

(4)

CPAN

(1)

Caspase-activated nuclease

(1)

Molecule type  (1)

Protein

(4)

Gene names  (6)

Cad

(3)

Dffb

(3)

CAD

(1)

DFF2

(1)

DFF40

(1)

DFFB

(1)

Interacting Molecules  (1)

DNA fragmentation factor subunit alpha

(2)

Interacting ligands  (3)

MG : MAGNESIUM ION

(1)

PB : LEAD (II) ION

(1)

ZN : ZINC ION

(1)

Biological function  (10)

DNA endonuclease activity

(4)

DNA binding

(1)

DNA nuclease activity

(1)

disordered domain specific binding

(1)

enzyme binding

(1)

hydrolase activity

(1)

identical protein binding

(1)

nuclease activity

(1)

protein binding

(1)

protein domain specific binding

(1)

Biological process  (5)

apoptotic DNA fragmentation

(4)

apoptotic process

(4)

DNA catabolic process

(1)

apoptotic chromosome condensation

(1)

negative regulation of apoptotic DNA fragmentation

(1)

Biological cell component  (7)

chromatin

(1)

cytoplasm

(1)

cytosol

(1)

nucleolus

(1)

nucleoplasm

(1)

nucleus

(1)

protein-containing complex

(1)

SCOP fold  (2)

beta-Grasp (ubiquitin-like)

(3)

His-Me finger endonucleases

(1)

SCOP family  (2)

CAD domain

(3)

Caspase-activated DNase, CAD (DffB, DFF40)

(1)

CATH class  (2)

Alpha Beta

(3)

Special

(1)

CATH topology  (2)

Ubiquitin-like (UB roll)

(3)

Helix Hairpins

(1)

Pfam accession / name  (2)

PF02017 : CIDE-N

(4)

PF09230 : DFF40

(1)

Diffraction protocol  (1)

Single wavelength

(1)

Diffraction radiation source type  (1)

Synchrotron

(1)

Diffraction source  (1)

NSLS BEAMLINE X12C

(1)

Synchrotron site  (1)

NSLS

(1)

Refinement software  (1)

CNS

(1)

NMR software packages  (4)

X-PLOR

(3)

DYANA

(1)

Felix

(1)

XEASY

(1)

NMR Field Strength

400.0 - 500

(3)

500.0 - 600

(3)

600.0 - 700

(2)

700.0 - 800

(2)

800.0 - 900

(1)

Representative Structures

100%

95%

90%

70%

50%

40%

30%