Uniprot accession / id : O70404  OR   Uniprot accession / id : Q9BV40
 
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Entry Information
Entry status  (1)
REL
(3)
 
Experimental methods  (1)
X-ray diffraction
(3)
 
Authors  (32)
Brunger AT
(1)
Cheng X
(1)
Diao J
(1)
Fu T
(1)
Gong X
(1)
Graham SC
(1)
Honing S
(1)
Höning S
(1)
Lai Y
(1)
Li J
(1)
Li M
(1)
Li Y
(1)
Liu J
(1)
Liu R
(1)
Miller SE
(1)
Owen DJ
(1)
Pan L
(1)
Pan LF
(1)
Peden AA
(1)
Pfuetzner RA
(1)
Robinson MS
(1)
Rong Y
(1)
Sahlender DA
(1)
Vivona S
(1)
Wang Y
(1)
Wilz LM
(1)
Xu X
(1)
Zhang J
(1)
Zhao M
(1)
Zhong Q
(1)
Zhou Q
(1)
Zhou Z
(1)
 
Homo / hetero assembly  (2)
hetero
(2)
homo
(1)
 
Assembly composition  (2)
protein/protein complex
(2)
protein structure
(1)
 
Assembly polymer count  (2)
tetramer
(2)
monomer
(1)
 
Resolution distribution
1.0 - 1.5
(1)
2.0 - 2.5
(1)
3.0 - 3.5
(1)
 
Release year distribution
2010 - 2015
(2)
2015 - 2020
(2)
2020 - 2025
(1)
 
Journal  (3)
Cell
(1)
Nature
(1)
Proc Natl Acad Sci U S A
(1)
 
Macromolecules
Organism superkingdom  (1)
Eukaryota
(3)
 
Organism name  (3)
Homo sapiens
(2)
Mus musculus
(1)
Rattus norvegicus
(1)
 
Molecule name  (8)
Endobrevin
(3)
VAMP-8
(3)
Vesicle-associated membrane protein 8
(3)
EDB
(2)
Clathrin assembly lymphoid myeloid leukemia protein
(1)
Edb
(1)
Phosphatidylinositol-binding clathrin assembly protein
(1)
rCALM
(1)
 
Molecule type  (1)
Protein
(3)
 
Gene names  (4)
VAMP8
(2)
Calm
(1)
Picalm
(1)
Vamp8
(1)
 
Interacting Molecules  (2)
Synaptosomal-associated protein 29
(2)
Syntaxin-17
(2)
 
Interacting ligands  (2)
GOL : GLYCEROL
(1)
PO4 : PHOSPHATE ION
(1)
 
Function and Biology
Biological function  (3)
1-phosphatidylinositol binding
(1)
clathrin binding
(1)
phospholipid binding
(1)
 
Biological process  (3)
vesicle-mediated transport
(2)
clathrin coat assembly
(1)
clathrin-dependent endocytosis
(1)
 
Biological cell component  (2)
membrane
(2)
clathrin-coated vesicle
(1)
 
Sequence and Structure classification
CATH class  (1)
Mainly Alpha
(2)
 
CATH topology  (3)
Methane Monooxygenase Hydroxylase; Chain G, domain 1
(1)
Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat
(1)
Single alpha-helices involved in coiled-coils or other helix-helix interfaces
(1)
 
Pfam accession / name  (2)
PF00957 : Synaptobrevin
(3)
PF07651 : ANTH
(1)
 
Experimental Information
Diffraction protocol  (1)
Single wavelength
(3)
 
Diffraction radiation source type  (1)
Synchrotron
(3)
 
Diffraction source  (3)
APS BEAMLINE 24-ID-C
(1)
DIAMOND BEAMLINE I03
(1)
SSRF BEAMLINE BL17U1
(1)
 
Synchrotron site  (3)
APS
(1)
Diamond
(1)
SSRF
(1)
 
Diffraction detector type  (2)
CCD
(2)
Pixel
(1)
 
Refinement software  (1)
PHENIX
(3)
 
Representative Structures
Representative Structures
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Entries 1 to 3 of 3
Entries 1 to 3 of 3
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Crystal structure of the autophagic STX17/SNAP29/VAMP8 SNARE complex
Li Y, Pan LF
Proc Natl Acad Sci U S A (2020) [PMID: 32817423  ]
Source organism: Homo sapiens  
Assembly composition: protein/protein complex
Assembly name: SNARE complex STX17-SNAP29-VAMP8 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-132004 (Preferred)   search this ID
PDBe-KB: Q9BV40    P56962    O95721   
X-ray diffraction
3.05Å resolution
Released: 2 Sep 2020
Model geometry
Fit model/data
7bv6
7bv6
7bv6
Structure of CALM (PICALM) in complex with VAMP8
Miller SE, Sahlender DA, Graham SC, Honing S, Robinson MS, Peden AA, Owen DJ
Cell (2011) [PMID: 22118466  ]
Assembly composition: protein only structure
Bound ligands: GOL    PO4   
Assembly name: Phosphatidylinositol-binding clathrin assembly protein, Vesicle-associated membrane protein 8 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-129531 (Preferred)   search this ID
PDBe-KB: O55012    O70404   
X-ray diffraction
2.03Å resolution
Released: 7 Dec 2011
Model geometry
Fit model/data
3zym
3zym
3zym
Crystal structure of autophagic SNARE complex
Zhao M, Brunger AT
Nature (2015) [PMID: 25686604  ]
Source organism: Homo sapiens  
Assembly composition: protein/protein complex
Assembly name: SNARE complex STX17-SNAP29-VAMP8 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-132004 (Preferred)   search this ID
PDBe-KB: Q9BV40    P56962    O95721   
X-ray diffraction
1.4Å resolution
Released: 11 Feb 2015
Model geometry
Fit model/data
4wy4
4wy4
4wy4
Entries 1 to 3 of 3
Entries 1 to 3 of 3