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Entry Information
Entry status
(1)
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(2)
Electron Microscopy
(1)
X-ray diffraction
(1)
Authors
(10)
Carr KH
(1)
Duan JS
(1)
Emsley J
(1)
Li R
(1)
McEwan PA
(1)
Mo X
(1)
Shu ZM
(1)
Yang W
(1)
Zheng X
(1)
Zhou AW
(1)
Homo / hetero assembly
(2)
hetero
(1)
homo
(1)
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(2)
protein structure
(1)
protein/protein complex
(1)
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(2)
heptamer
(1)
monomer
(1)
Resolution distribution
2.0 - 2.5
(1)
3.0 - 3.5
(1)
Release year distribution
2010 - 2015
(1)
2020 - 2025
(1)
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(2)
Blood
(1)
To be published
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Macromolecules
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(1)
Eukaryota
(2)
Organism name
(1)
Homo sapiens
(2)
Molecule name
(9)
GP-IX
(2)
GPIX
(2)
Glycoprotein 9
(2)
Platelet glycoprotein IX
(2)
Antigen CD42b-beta
(1)
GP-Ib beta
(1)
GPIb-beta
(1)
GPIbB
(1)
Platelet glycoprotein Ib beta chain
(1)
Molecule type
(1)
Protein
(2)
Gene names
(2)
GP9
(2)
GP1BB
(1)
Interacting Molecules
(2)
Platelet glycoprotein Ib alpha chain
(1)
Platelet glycoprotein Ib beta chain
(1)
Interacting ligands
(3)
NAG : 2-acetamido-2-deoxy-beta-D-glucopyranose
(2)
BMA : beta-D-mannopyranose
(1)
PEG : DI(HYDROXYETHYL)ETHER
(1)
Function and Biology
Biological function
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protein binding
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Biological process
(7)
blood coagulation
(1)
blood coagulation, intrinsic pathway
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cell adhesion
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hemostasis
(1)
megakaryocyte development
(1)
positive regulation of platelet activation
(1)
release of sequestered calcium ion into cytosol
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Biological cell component
(3)
glycoprotein Ib-IX-V complex
(1)
membrane
(1)
plasma membrane
(1)
Sequence and Structure classification
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Alpha Beta
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Leucine-rich repeat, LRR (right-handed beta-alpha superhelix)
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Pfam accession / name
(2)
PF01462 : LRRNT
(2)
PF13855 : LRR_8
(2)
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ESRF BEAMLINE ID29
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GATAN K3 (6k x 4k)
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Representative Structures
Representative Structures
Entries
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Entries 1 to 2 of 2
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Cryo-EM structure of GPIb-IX Complex
Shu ZM, Duan JS, Zhou AW
To be published
Source organism: Homo sapiens
Assembly composition: protein/protein complex
Carbohydrate polymer components:
Molecule 1 -
NAG(2)
Molecule 2 -
BMA(1), NAG(2)
PDBe complex ID:
PDB-CPX-283209 (Preferred)
search this ID
PDBe-KB:
glycoprotein GPIb variant
McEwan PA, Yang W, Carr KH, Mo X, Zheng X, Li R, Emsley J
Blood
(2011)
[PMID: 21908432 ]
Source organism: Homo sapiens
Assembly composition: protein only structure
Assembly name:
Platelet glycoprotein IX, Platelet glycoprotein Ib beta chain
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-146512 (Preferred)
search this ID
Entries 1 to 2 of 2