Entry status  (1)

REL

(14)

Experimental methods  (1)

X-ray diffraction

(14)

Authors  (67)

Ehler A

(5)

Rudolph MG

(5)

Benz J

(4)

Schlatter D

(4)

Allison T

(3)

Allison TJ

(3)

Barrow JC

(3)

Hall DL

(3)

Harrison ST

(3)

Hutson PH

(3)

Kett NR

(3)

Melamed JY

(3)

Mulhearn JJ

(3)

Patel SB

(3)

Poslusney MS

(3)

Robinson RG

(3)

Sachs NA

(3)

Sanders JM

(3)

Schubert JW

(3)

Sharma S

(3)

Smith RF

(3)

Soisson SM

(3)

Wolkenberg S

(3)

Wolkenberg SE

(3)

Zhao Z

(3)

Baxter NJ

(2)

Cliff MJ

(2)

Czarnota S

(2)

Hay S

(2)

Johannissen LO

(2)

Le Trong I

(2)

Levy CW

(2)

Parson WW

(2)

Rummel F

(2)

Rutherford K

(2)

Scrutton NS

(2)

Stenkamp RE

(2)

Waltho JP

(2)

Wilson AL

(2)

Ambrus G

(1)

Cole DC

(1)

Davenport R

(1)

Ellery J

(1)

Fosbeary R

(1)

Hixon MS

(1)

Jennings AJ

(1)

Kadotani A

(1)

Kamada Y

(1)

Kamran R

(1)

Kiyotani T

(1)

Lanier M

(1)

Lerner C

(1)

Matsumoto S

(1)

Mizukami A

(1)

Momose T

(1)

Nakatsu M

(1)

Nonaka Y

(1)

Okada K

(1)

Okazaki K

(1)

Okubo S

(1)

Ozawa M

(1)

Ozawa T

(1)

Saikatendu K

(1)

Takase Y

(1)

Tsuji E

(1)

Walsh L

(1)

Wu H

(1)

Homo / hetero assembly  (1)

homo

(14)

Assembly composition  (1)

protein structure

(14)

Assembly polymer count  (1)

monomer

(14)

Resolution distribution

1.0 - 1.5

(6)

1.5 - 2

(3)

2.0 - 2.5

(4)

2.5 - 3

(1)

Release year distribution

2005 - 2010

(3)

2010 - 2015

(9)

2015 - 2020

(6)

Journal  (6)

Acta Crystallogr D Biol Crystallogr

(4)

ACS Med Chem Lett

(3)

ACS Catal

(2)

J Mol Biol

(2)

To be published

(2)

J Med Chem

(1)

Organism superkingdom  (1)

Eukaryota

(14)

Organism name  (2)

Homo sapiens

(12)

Mus musculus

(2)

Molecule name  (1)

Catechol O-methyltransferase

(14)

Molecule type  (1)

Protein

(14)

Gene names  (3)

COMT

(12)

Comt

(2)

Comt1

(2)

Interacting ligands  (14)

MG : MAGNESIUM ION

(11)

SAM : S-ADENOSYLMETHIONINE

(8)

DNC : 3,5-DINITROCATECHOL

(6)

NA : SODIUM ION

(4)

CL : CHLORIDE ION

(3)

2F6 : 1',3'-dimethyl-1H,1'H-3,4'-bipyrazole

(1)

43G : 1-(biphenyl-3-yl)-3-hydroxypyridin-4(1H)-one

(1)

43H : [1-(biphenyl-3-yl)-5-hydroxy-4-oxo-1,4-dihydropyridin-3-yl]boronic acid

(1)

43J : 2-(biphenyl-3-yl)-5-hydroxy-3-methylpyrimidin-4(3H)-one

(1)

K : POTASSIUM ION

(1)

MPD : (4S)-2-METHYL-2,4-PENTANEDIOL

(1)

PI : HYDROGENPHOSPHATE ION

(1)

PO4 : PHOSPHATE ION

(1)

SFG : SINEFUNGIN

(1)

EC number / name  (1)

2.1.1.6 : Catechol O-methyltransferase

(14)

Biological function  (3)

O-methyltransferase activity

(14)

catechol O-methyltransferase activity

(14)

magnesium ion binding

(14)

Biological process  (1)

catecholamine metabolic process

(14)

Compound cofactor class  (1)

S-adenosylmethionine

(9)

CATH class  (1)

Alpha Beta

(12)

CATH topology  (1)

Rossmann fold

(12)

Pfam accession / name  (1)

PF01596 : Methyltransf_3

(14)

Diffraction protocol  (1)

Single wavelength

(14)

Diffraction radiation source type  (2)

Synchrotron

(11)

Rotating anode

(3)

Diffraction source  (9)

SLS BEAMLINE X10SA

(5)

RIGAKU FR-E+ SUPERBRIGHT

(2)

ALS BEAMLINE 5.0.3

(1)

APS BEAMLINE 17-ID

(1)

APS BEAMLINE 23-ID-D

(1)

DIAMOND BEAMLINE I04

(1)

DIAMOND BEAMLINE I04-1

(1)

RIGAKU MICROMAX-007

(1)

SPRING-8 BEAMLINE BL32B2

(1)

Synchrotron site  (5)

SLS

(5)

APS

(2)

Diamond

(2)

ALS

(1)

SPring-8

(1)

Diffraction detector type  (3)

CCD

(7)

Pixel

(5)

Image plate

(2)

Refinement software  (2)

REFMAC

(8)

PHENIX

(6)

Representative Structures

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