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(20)
Almo SC
(8)
Cheng H
(8)
Zhan C
(8)
Nathenson SG
(7)
Bonanno JB
(5)
Liu W
(5)
Ramagopal U
(5)
Atoms-to-Animals: The Immune Function Network (IFN)
(4)
New York Structural Genomics Research Consortium (NYSGRC)
(4)
Ramagopal UA
(4)
Toro R
(4)
Brenowitz M
(3)
Hui X
(3)
Kumar PR
(3)
Li Z
(3)
Patskovsky Y
(3)
Yan Q
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(2)
Bhosle RC
(2)
Sampathkumar P
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protein/protein complex
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protein structure
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(3)
hexamer
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2.0 - 2.5
(4)
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(3)
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2005 - 2010
(1)
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(7)
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Molecule name
(35)
DcR3
(8)
Decoy receptor 3
(8)
Decoy receptor for Fas ligand
(8)
M68
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Tumor necrosis factor receptor superfamily member 6B
(8)
HVEM-L
(3)
Herpes virus entry mediator ligand
(3)
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(3)
Tumor necrosis factor ligand superfamily member 14
(3)
Tumor necrosis factor ligand superfamily member 14, membrane form
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(3)
ADAM10-processed FasL form
(2)
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TNF ligand-related molecule 1
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Tumor necrosis factor ligand superfamily member 15
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(2)
Vascular endothelial cell growth inhibitor
(2)
sFasL
(2)
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Protein
(8)
Gene names
(16)
DCR3
(8)
TNFRSF6B
(8)
TR6
(8)
UNQ186/PRO212
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(3)
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APT1LG1
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CD95L
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Tumor necrosis factor receptor superfamily member 6B
(7)
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(3)
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(2)
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Interacting ligands
(6)
MG : MAGNESIUM ION
(4)
BMA : beta-D-mannopyranose
(3)
MAN : alpha-D-mannopyranose
(3)
NAG : 2-acetamido-2-deoxy-beta-D-glucopyranose
(3)
CL : CHLORIDE ION
(1)
GOL : GLYCEROL
(1)
Function and Biology
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tumor necrosis factor receptor binding
(7)
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immune response
(7)
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membrane
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Sequence and Structure classification
CATH class
(1)
Mainly Beta
(8)
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(2)
Tumor Necrosis Factor Receptor, subunit A; domain 2
(8)
Jelly Rolls
(7)
Pfam accession / name
(2)
PF00020 : TNFR_c6
(8)
PF00229 : TNF
(7)
Experimental Information
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(8)
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(8)
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(3)
NSLS BEAMLINE X29A
(6)
APS BEAMLINE 24-ID-E
(1)
APS BEAMLINE 31-ID
(1)
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(8)
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Representative Structures
Representative Structures
Entries
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Entries 1 to 8 of 8
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Crystal structure of light mutant2 and dcr3 complex
Liu W, Bonanno JB, Zhan C, Kumar PR, Toro R, Nathenson SG, Almo SC, Atoms-to-Animals: The Immune Function Network (IFN), New York Structural Genomics Research Consortium (NYSGRC)
Structure
(2014)
[PMID: 25087510 ]
Source organism: Homo sapiens
Assembly composition: protein/protein complex
Carbohydrate polymer components:
Molecule 1 -
BMA(1), MAN(1), NAG(2)
Molecule 2 -
NAG(2)
Assembly name:
Tumor necrosis factor ligand superfamily member 14, soluble form and Tumor necrosis factor receptor superfamily member 6B
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-128994 (Preferred)
search this ID
CRYSTAL STRUCTURE OF LIGHT AND DcR3 COMPLEX
Liu W, Zhan C, Bonanno JB, Bhosle RC, Nathenson SG, Almo SC, Atoms-to-Animals: The Immune Function Network (IFN), New York Structural Genomics Research Consortium (NYSGRC)
Structure
(2014)
[PMID: 25087510 ]
Source organism: Homo sapiens
Assembly composition: protein/protein complex
Carbohydrate polymer components:
Molecule 1 -
BMA(1), MAN(1), NAG(2)
Assembly name:
Tumor necrosis factor ligand superfamily member 14, soluble form and Tumor necrosis factor receptor superfamily member 6B
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-128994 (Preferred)
search this ID
Crystal Structure of a human FasL mutant in complex with human DcR3
Liu W, Bonanno JB, Almo SC
Structure
(2016)
[PMID: 27806260 ]
Source organism: Homo sapiens
Assembly composition: protein/protein complex
Assembly name:
Tumor necrosis factor receptor superfamily member 6B and Tumor necrosis factor ligand superfamily member 6, soluble form
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-131928 (Preferred)
search this ID
Crystal structure of a human light loop mutant in complex with dcr3
Liu W, Zhan C, Bonanno JB, Sampathkumar P, Toro R, Nathenson SG, Almo SC, New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN)
Structure
(2014)
[PMID: 25087510 ]
Source organism: Homo sapiens
Assembly composition: protein/protein complex
Carbohydrate polymer components:
Molecule 1 -
BMA(1), MAN(1), NAG(2)
Molecule 2 -
NAG(2)
Assembly name:
Tumor necrosis factor ligand superfamily member 14, soluble form and Tumor necrosis factor receptor superfamily member 6B
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-128994 (Preferred)
search this ID
Crystal structure of FASL and DcR3 complex
Liu W, Ramagopal UA, Zhan C, Bonanno JB, Bhosle RC, Nathenson SG, Almo SC, Atoms-to-Animals: The Immune Function Network (IFN), New York Structural Genomics Research Consortium (NYSGRC)
Structure
(2016)
[PMID: 27806260 ]
Source organism: Homo sapiens
Assembly composition: protein/protein complex
Assembly name:
Tumor necrosis factor receptor superfamily member 6B and Tumor necrosis factor ligand superfamily member 6, soluble form
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-131928 (Preferred)
search this ID
The structure of TL1A-DCR3 COMPLEX
Zhan C, Patskovsky Y, Yan Q, Li Z, Ramagopal UA, Nathenson SG, Almo SC
Structure
(2011)
[PMID: 21300286 ]
Source organism: Homo sapiens
Assembly composition: protein/protein complex
Assembly name:
Tumor necrosis factor receptor superfamily member 6B and Tumor necrosis factor ligand superfamily member 15, secreted form
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-131829 (Preferred)
search this ID
Crystal Structure of DcR3-TL1A complex
Zhan C, Patskovsky Y, Yan Q, Li Z, Ramagopal UA, Nathenson SG, Almo SC
Structure
(2011)
[PMID: 21300286 ]
Source organism: Homo sapiens
Assembly composition: protein/protein complex
Assembly name:
Tumor necrosis factor receptor superfamily member 6B and Tumor necrosis factor ligand superfamily member 15, secreted form
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-131829 (Preferred)
search this ID
Crystal structure of DCR3
Zhan C, Patskovsky Y, Yan Q, Li Z, Ramagopal UA, Nathenson SG, Almo SC
Structure
(2011)
[PMID: 21300286 ]
Source organism: Homo sapiens
Assembly composition: protein only structure
Assembly name:
Tumor necrosis factor receptor superfamily member 6B
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-131927 (Preferred)
search this ID

Entries 1 to 8 of 8