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X-ray diffraction
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Eigenbrot C
(20)
Corson LB
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Ultsch M
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Wei B
(19)
Chen J
(18)
Malek S
(18)
Peterson D
(18)
Robarge K
(18)
Sideris S
(18)
Yen I
(18)
Ding CZ
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Dragovich PS
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Fauber BP
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Purkey HE
(17)
Yue Q
(17)
Zhou A
(16)
Ge H
(15)
Ma S
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Salphati L
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Zhang H
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Liu Y
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Ho Q
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Labadie SS
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Lai KW
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Li C
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Chen Z
(11)
Evangelista M
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Hitz A
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O'Brien T
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Pang J
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DiPasquale AG
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Liu W
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Labadie S
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Benavides GA
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Cheff DM
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Darley-Usmar VM
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Davies DR
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Dranow DM
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Flint AJ
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Goa Z
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Hall MD
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Hu X
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Jadhav A
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Lee TD
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Maloney DJ
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Moore WJ
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Mott BT
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Pohida K
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Rai G
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Simeonov A
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Stott GM
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Urban DJ
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Waterson AG
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Yang SM
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Zhu H
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VanderPorten E
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Kouznetsova J
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Kuenstner EJ
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Luci DK
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Lukacs CM
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Neckers LM
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Sulikowski G
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Xu Q
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Zhang X
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Boggs J
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Craig L
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Hunsaker T
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Mosi R
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Shen DL
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Sun J
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Chung T-W
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Chung TW
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Gao Z
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Ha K-T
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Ha KT
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Han CW
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Jang SB
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Jeong MS
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Kwon YJ
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Lee H
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Park KH
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Park SY
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Wang J
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Yoon D
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Homo / hetero assembly
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1.5 - 2
(11)
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Acta Crystallogr D Biol Crystallogr
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Cell proliferation-inducing gene 19 protein
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L-lactate dehydrogenase A chain
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LDH muscle subunit
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LDH-A
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LDH-M
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Renal carcinoma antigen NY-REN-59
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Representative Structures
Representative Structures
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Entries 1 to 10 of 45
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Human Lactate Dehydrogenase A in Complex with Inhibitor CHK-336
Lowther WT, Gumpena R
To be published
Source organism: Homo sapiens
Assembly composition: protein only structure
Assembly name:
L-lactate dehydrogenase A complex
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-132412 (Preferred)
search this ID

LDHA structure in complex with inhibitor 14
Eigenbrot CE, Ultsch M, Wei B
To be published
Source organism: Homo sapiens
Assembly composition: protein only structure
Assembly name:
L-lactate dehydrogenase A complex
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-132412 (Preferred)
search this ID

LDHA-mla
Han CW, Jang SB
Cancers (Basel)
(2019)
[PMID: 31324019 ]
Source organism: Homo sapiens
Assembly composition: protein only structure
Bound ligands:
MLI
Assembly name:
L-lactate dehydrogenase A complex
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-132412 (Preferred)
search this ID

Lactate Dehydrogenase in complex with hydroxylactam inhibitor compound 9: (6R)-3-[(2-chlorophenyl)sulfanyl]-4-hydroxy-6-(3-hydroxyphenyl)-6-(thiophen-3-yl)-5,6-dihydropyridin-2(1H)-one
Ultsch M, Eigenbrot C
ACS Med Chem Lett
(2016)
[PMID: 27774125 ]
Source organism: Homo sapiens
Assembly composition: protein only structure
Assembly name:
L-lactate dehydrogenase A complex
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-132412 (Preferred)
search this ID

Crystal Structure of Lactate Dehydrogenase A in complex with inhibitor compound 29 and NADH
Lukacs CM, Dranow DM
J Med Chem
(2017)
[PMID: 29120638 ]
Source organism: Homo sapiens
Assembly composition: protein only structure
Assembly name:
L-lactate dehydrogenase A complex
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-132412 (Preferred)
search this ID

Crystal Structure of Lactate Dehydrogenase A in complex with inhibitor compound 23 and Zinc
Lukacs CM, Abendroth J
J Med Chem
(2017)
[PMID: 29120638 ]
Source organism: Homo sapiens
Assembly composition: protein only structure
Assembly name:
L-lactate dehydrogenase A complex
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-132412 (Preferred)
search this ID

Lactate Dehydrogenase in complex with hydroxylactam inhibitor compound 31: (2~{S})-5-(2-chlorophenyl)sulfanyl-2-(4-morpholin-4-ylphenyl)-4-oxidanyl-2-thiophen-3-yl-1,3-dihydropyridin-6-one
Chen Z, Eigenbrot C
ACS Med Chem Lett
(2016)
[PMID: 27774125 ]
Source organism: Homo sapiens
Assembly composition: protein only structure
Assembly name:
L-lactate dehydrogenase A complex
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-132412 (Preferred)
search this ID

Crystal Structure of Lactate Dehydrogenase A in complex with inhibitor compound 59 and NADH
Davies DR, Dranow DM
J Med Chem
(2017)
[PMID: 29120638 ]
Source organism: Homo sapiens
Assembly composition: protein only structure
Assembly name:
L-lactate dehydrogenase A complex
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-132412 (Preferred)
search this ID

Crystal Structure of Lactate Dehydrogenase A in complex with inhibitor compound 29
Lukacs CM, Moulin A
J Med Chem
(2017)
[PMID: 29120638 ]
Source organism: Homo sapiens
Assembly composition: protein only structure
Assembly name:
L-lactate dehydrogenase A complex
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-132412 (Preferred)
search this ID

Crystal Structure of Lactate Dehydrogenase A in complex with inhibitor compound 11
Lukacs CM, Dranow DM
J Med Chem
(2017)
[PMID: 29120638 ]
Source organism: Homo sapiens
Assembly composition: protein only structure
Assembly name:
L-lactate dehydrogenase A complex
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-132412 (Preferred)
search this ID

Entries 1 to 10 of 45