Entry status  (1)

REL

(79)

Experimental methods  (3)

X-ray diffraction

(50)

Electron Microscopy

(26)

Solution NMR

(3)

Authors  (332)

Kwong PD

(27)

Sodroski J

(18)

Wyatt R

(18)

Bjorkman PJ

(13)

Hendrickson WA

(13)

Dimitrov DS

(12)

Zhang MY

(12)

Zhou T

(12)

Burton DR

(11)

Arthos J

(10)

Nabel GJ

(10)

Ward AB

(10)

Xiang SH

(10)

Dey B

(9)

Hessell AJ

(9)

Van Ryk D

(9)

Xu L

(9)

Yang X

(9)

Zwick MB

(9)

Huang CC

(8)

Sweet RW

(8)

Majeed S

(7)

Ozorowski G

(7)

Torres JL

(7)

Wang H

(7)

Yang Z

(7)

Forli S

(6)

Robinson J

(6)

Santos-Martins D

(6)

Wilson IA

(6)

Wu H

(6)

Kong L

(5)

Kwon YD

(5)

Acharya P

(4)

Evans PR

(4)

Höning S

(4)

Kelly BT

(4)

McCoy AJ

(4)

Owen DJ

(4)

Pancera M

(4)

Robinson JE

(4)

Stanfield RL

(4)

Brouillette CG

(3)

Chaiken IM

(3)

Chen B

(3)

Cupo A

(3)

Dam KA

(3)

Gao H

(3)

Gristick HB

(3)

Hong X

(3)

Liu J

(3)

Lu J

(3)

Mariuzza RA

(3)

Moore JP

(3)

Myszka D

(3)

Myszka DG

(3)

Nussenzweig MC

(3)

Rits-Volloch S

(3)

Scharf L

(3)

Tendian SW

(3)

Wang XX

(3)

Yin Y

(3)

Ban YE

(2)

Barnes CO

(2)

Bjorkman P

(2)

Bylund T

(2)

Chen L

(2)

Chen S

(2)

Choe H

(2)

Concha N

(2)

Concha NO

(2)

DeVico AL

(2)

Ding B

(2)

Dixon DP

(2)

Fan C

(2)

Farzan M

(2)

Fellinger C

(2)

Flinko R

(2)

Foulke JS

(2)

Gao W

(2)

Gohain N

(2)

Guan Y

(2)

Herrmann T

(2)

Hoening S

(2)

Honing S

(2)

Hu G

(2)

Hua Y

(2)

Huang C-C

(2)

Huang W

(2)

Julien JP

(2)

Kadlecova Z

(2)

Kamenicky J

(2)

Kamin-Lewis R

(2)

Krystal M

(2)

Lee JH

(2)

Lewis GK

(2)

Li Y

(2)

Liao M

(2)

Liu AZ

(2)

Liu T

(2)

 

More...

Homo / hetero assembly  (2)

hetero

(68)

homo

(11)

Assembly composition  (2)

protein/protein complex

(68)

protein structure

(11)

Assembly polymer count  (13)

tetramer

(28)

pentadecamer

(10)

dimer

(8)

monomer

(8)

hexamer

(4)

nonamer

(4)

trimer

(4)

21-mer

(3)

heptamer

(3)

pentamer

(3)

octadecamer

(2)

dodecamer

(1)

octamer

(1)

Resolution distribution

1.5 - 2

(8)

2.0 - 2.5

(13)

2.5 - 3

(11)

3.0 - 3.5

(12)

3.5 - 4

(16)

4.0 - 4.5

(6)

4.5 - 5

(2)

6.5 - 7

(1)

8.5 - 9

(2)

16.5 - 17

(1)

19.5 - 20

(1)

22.5 - 23

(1)

Release year distribution

1990 - 1995

(3)

1995 - 2000

(10)

2000 - 2005

(7)

2005 - 2010

(19)

2010 - 2015

(16)

2015 - 2020

(25)

2020 - 2025

(16)

Journal  (18)

Nature

(20)

Proc Natl Acad Sci U S A

(12)

Cell Rep

(7)

Nat Struct Mol Biol

(7)

J Virol

(6)

Structure

(6)

J Mol Biol

(4)

Cell

(3)

Science

(3)

Cell Host Microbe

(2)

Dev Cell

(2)

Biochem Biophys Res Commun

(1)

Biochim Biophys Acta

(1)

J Biomed Sci

(1)

Proteins

(1)

Sci Rep

(1)

Sci Transl Med

(1)

To be published

(1)

Organism superkingdom  (1)

Eukaryota

(79)

Organism name  (1)

Homo sapiens

(79)

Molecule name  (2)

T-cell surface antigen T4/Leu-3

(79)

T-cell surface glycoprotein CD4

(79)

Molecule type  (1)

Protein

(79)

Gene names  (1)

CD4

(79)

Interacting Molecules  (86)

Envelope glycoprotein gp160

(29)

Surface protein gp120

(18)

Transmembrane protein gp41

(17)

Ig-like domain-containing protein

(10)

ANTIBODY 17B, HEAVY CHAIN

(9)

17b Fab heavy chain

(6)

17b Fab light chain

(6)

AP-2 complex subunit alpha-2

(5)

AP-2 complex subunit beta

(5)

AP-2 complex subunit mu

(5)

AP-2 complex subunit sigma

(5)

ANTIBODY 17B, LIGHT CHAIN

(4)

Human immunodeficiency virus 1 envelope glycoprotein Gp120 domain-containing protein

(4)

HLA class II histocompatibility antigen, DR alpha chain

(3)

HLA class II histocompatibility antigen, DRB1 beta chain

(3)

Antibody 36D5 heavy chain

(2)

Antibody 36D5 light chain

(2)

C-C chemokine receptor type 5

(2)

E51 Fab heavy chain

(2)

E51 Fab light chain

(2)

FAB 48D LIGHT CHAIN

(2)

FAB OF BROADLY NEUTRALIZING ANTIBODY 17B

(2)

HIV-1 GP120 ENVELOPE GLYCOPROTEIN

(2)

Hemagglutinin HA1 chain

(2)

TGN38 CARGO PEPTIDE

(2)

17b Fab Heavy Chain

(1)

17b Fab Light Chain

(1)

17b Fab VH domain

(1)

17b Fab VL domain

(1)

17b Heavy chain

(1)

17b Light chain

(1)

21c Fab VH domain

(1)

21c Fab VL domain

(1)

8ANC195 Fab heavy chain

(1)

8ANC195 Fab light chain

(1)

8ANC195 G52K5 Fab VH domain

(1)

8ANC195 G52K5 Fab VL domain

(1)

8ANC195 G52K5 VH domain

(1)

8ANC195 G52K5 VL domain

(1)

ANTIBODY 17B

(1)

Adnectin

(1)

Adnectin 6940_B01

(1)

Antibody 2.2c, Heavy chain

(1)

Antibody 2.2c, Light chain

(1)

BG505 SOSIP.664 gp140

(1)

Broadly neutralizing darpin bnd.9

(1)

CG10 Fab heavy chain

(1)

CG10 Fab light chain

(1)

Envelope glycoprotein gp41

(1)

FAB 48D HEAVY CHAIN

(1)

FAB 48D Heavy CHAIN

(1)

FAB HEAVY CHAIN OF ADCC AND NON-NEUTRALIZING ANTI-HIV-1 ANTIBODY N5-I5

(1)

FAB LIGHT CHAIN OF ADCC AND NON-NEUTRALIZING ANTI-HIV-1 ANTIBODY N5-I5

(1)

FAB OF BROADLY NEUTRALIZING ANTIBODY 8ANC195

(1)

FAB OF BROADLY NEUTRALIZING ANTIBODY 8ANC195 VARIANT G52K5

(1)

Fab heavy chain

(1)

Fab light chain

(1)

Focal adhesion kinase 1

(1)

H-2 class II histocompatibility antigen, A-K alpha chain

(1)

H-2 class II histocompatibility antigen, A-K beta chain

(1)

Heavy chain of anti HIV Fab from human 21c antibody

(1)

Heavy chain of murine 2D5 Fab

(1)

Ibalizumab Heavy Chain

(1)

Ibalizumab Light Chain

(1)

Immunoglobulin gamma-1 heavy chain

(1)

Immunoglobulin lambda constant 3

(1)

Light chain of anti HIV Fab from human 21c antibody

(1)

Light chain of murine 2D5 Fab

(1)

NB457

(1)

Ovotransferrin

(1)

PGT 135 Heavy chain

(1)

PGT 135 Light chain

(1)

PGT145 heavy chain

(1)

PGT145 light chain

(1)

Protein Nef

(1)

T cell receptor alpha chain constant

(1)

T cell receptor beta constant 2

(1)

Tyrosine-protein kinase Lck

(1)

anti-HIV-1 antibody 412d light chain

(1)

anti-HIV-1 gp120 immunoglobulin X5 heavy chain

(1)

anti-HIV-1 gp120 immunoglobulin X5 light chain

(1)

envelope glycoprotein gp41

(1)

ibalizumab heavy chain

(1)

ibalizumab light chain

(1)

monoclonal antibody 17b heavy chain

(1)

monoclonal antibody 17b light chain

(1)

Interacting ligands  (11)

NAG : 2-acetamido-2-deoxy-beta-D-glucopyranose

(7)

BMA : beta-D-mannopyranose

(1)

EDO : 1,2-ETHANEDIOL

(1)

FUC : alpha-L-fucopyranose

(1)

GOL : GLYCEROL

(1)

IPA : ISOPROPYL ALCOHOL

(1)

MAN : alpha-D-mannopyranose

(1)

MLA : MALONIC ACID

(1)

MRD : (4R)-2-METHYLPENTANE-2,4-DIOL

(1)

SO4 : SULFATE ION

(1)

ZN : ZINC ION

(1)

Biological function  (1)

coreceptor activity

(11)

Biological process  (2)

cell adhesion

(70)

immune response

(11)

Biological cell component  (1)

membrane

(70)

SCOP fold  (2)

Immunoglobulin-like beta-sandwich

(26)

CD4 and CD8 receptor regions

(2)

SCOP family  (3)

C2 set domains

(26)

V set domains (antibody variable domain-like)

(26)

CD4 and CD8 receptor regions

(2)

CATH class  (2)

Mainly Beta

(40)

Mainly Alpha

(1)

CATH topology  (2)

Immunoglobulin-like

(40)

Single alpha-helices involved in coiled-coils or other helix-helix interfaces

(1)

Pfam accession / name  (4)

PF00047 : ig

(70)

PF05790 : C2-set

(70)

PF09191 : CD4-extracel

(11)

PF12104 : Tcell_CD4_C

(9)

Diffraction protocol  (1)

Single wavelength

(42)

Diffraction radiation source type  (1)

Synchrotron

(44)

Diffraction source  (19)

APS BEAMLINE 22-ID

(15)

NSLS BEAMLINE X4A

(6)

SSRL BEAMLINE BL12-2

(4)

APS BEAMLINE 23-ID-B

(2)

DIAMOND BEAMLINE I03

(2)

NSLS BEAMLINE X29A

(2)

ALS BEAMLINE 5.0.2

(1)

APS BEAMLINE 19-ID

(1)

APS BEAMLINE 22-BM

(1)

APS BEAMLINE 24-ID-C

(1)

BSRF BEAMLINE 3W1A

(1)

CHESS BEAMLINE F1

(1)

DIAMOND BEAMLINE I02

(1)

DIAMOND BEAMLINE I04-1

(1)

ESRF BEAMLINE BM30A

(1)

NSLS BEAMLINE X25

(1)

NSLS-II BEAMLINE 17-ID-2

(1)

SSRF BEAMLINE BL19U1

(1)

SSRL BEAMLINE BL7-1

(1)

Synchrotron site  (10)

APS

(20)

NSLS

(9)

SSRL

(5)

Diamond

(4)

ALS

(1)

BSRF

(1)

CHESS

(1)

ESRF

(1)

NSLS-II

(1)

SSRF

(1)

Diffraction detector type  (3)

CCD

(27)

Image plate

(8)

Pixel

(8)

Refinement software  (6)

PHENIX

(23)

REFMAC

(17)

X-PLOR

(11)

CNS

(9)

PROLSQ

(2)

phenix.real_space_refine

(2)

EM microscope model  (5)

FEI TITAN KRIOS

(19)

FEI POLARA 300

(3)

FEI TALOS ARCTICA

(2)

FEI TECNAI 12

(1)

FEI TECNAI F30

(1)

EM detector name  (8)

GATAN K2 SUMMIT (4k x 4k)

(16)

GATAN K3 (6k x 4k)

(3)

TVIPS TEMCAM-F415 (4k x 4k)

(2)

FEI FALCON III (4k x 4k)

(1)

GATAN K2 (4k x 4k)

(1)

GATAN K3 BIOQUANTUM (6k x 4k)

(1)

GATAN ULTRASCAN 1000 (2k x 2k)

(1)

GENERIC CCD

(1)

NMR software packages  (6)

X-PLOR

(2)

CARA

(1)

CYANA

(1)

DYANA

(1)

Felix

(1)

NDEE

(1)

NMR Field Strength

400.0 - 500

(1)

500.0 - 600

(3)

600.0 - 700

(2)

700.0 - 800

(2)

800.0 - 900

(1)

Representative Structures

100%

95%

90%

70%

50%

40%

30%