Entry status  (1)

REL

(3)

Experimental methods  (2)

X-ray diffraction

(2)

Solution NMR

(1)

Authors  (22)

Aoki KH

(3)

Cheetham JC

(3)

Egrie J

(3)

Syed RS

(3)

Chirino AJ

(2)

Elliott S

(2)

Finer-Moore J

(2)

Katz BA

(2)

Li C

(2)

Liu B

(2)

Matthews DJ

(2)

Osslund TD

(2)

Reid SW

(2)

Sitney K

(2)

Stroud RM

(2)

Wendoloski JJ

(2)

Zhan H

(2)

Zhang J

(2)

Harvey TS

(1)

Hoeffel TJ

(1)

Smith DM

(1)

Stevenson JL

(1)

Homo / hetero assembly  (2)

hetero

(2)

homo

(1)

Assembly composition  (2)

protein/protein complex

(2)

protein structure

(1)

Assembly polymer count  (2)

trimer

(2)

monomer

(1)

Resolution distribution

1.5 - 2

(1)

2.5 - 3

(1)

Release year distribution

1995 - 2000

(3)

Journal  (2)

Nature

(2)

Nat Struct Biol

(1)

Organism superkingdom  (1)

Eukaryota

(3)

Organism name  (1)

Homo sapiens

(3)

Molecule name  (1)

Erythropoietin

(3)

Molecule type  (1)

Protein

(3)

Gene names  (1)

EPO

(3)

Interacting Molecules  (1)

Erythropoietin receptor

(2)

Biological function  (5)

cytokine activity

(3)

erythropoietin receptor binding

(3)

hormone activity

(3)

protein binding

(3)

protein kinase activator activity

(3)

Biological process  (38)

acute-phase response

(3)

apoptotic process

(3)

blood circulation

(3)

cell surface receptor signaling pathway via STAT

(3)

cellular hyperosmotic response

(3)

embryo implantation

(3)

erythrocyte differentiation

(3)

erythrocyte maturation

(3)

erythropoietin-mediated signaling pathway

(3)

hemoglobin biosynthetic process

(3)

myeloid cell apoptotic process

(3)

negative regulation of apoptotic process

(3)

negative regulation of calcium ion transport into cytosol

(3)

negative regulation of erythrocyte apoptotic process

(3)

negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress

(3)

negative regulation of myeloid cell apoptotic process

(3)

negative regulation of transcription by RNA polymerase II

(3)

positive regulation of DNA-templated transcription

(3)

positive regulation of ERK1 and ERK2 cascade

(3)

positive regulation of Ras protein signal transduction

(3)

positive regulation of activated T cell proliferation

(3)

positive regulation of cell population proliferation

(3)

positive regulation of neuron differentiation

(3)

positive regulation of neuron projection development

(3)

regulation of transcription by RNA polymerase II

(3)

response to axon injury

(3)

response to dexamethasone

(3)

response to electrical stimulus

(3)

response to estrogen

(3)

response to hyperoxia

(3)

response to hypoxia

(3)

response to interleukin-1

(3)

response to lipopolysaccharide

(3)

response to nutrient

(3)

response to salt stress

(3)

response to testosterone

(3)

response to vitamin A

(3)

signal transduction

(3)

Biological cell component  (4)

cell body

(3)

cell surface

(3)

extracellular region

(3)

extracellular space

(3)

SCOP fold  (1)

4-helical cytokines

(3)

SCOP family  (1)

Short-chain cytokines

(3)

CATH class  (1)

Mainly Alpha

(3)

CATH topology  (1)

Growth Hormone; Chain: A;

(3)

Pfam accession / name  (1)

PF00758 : EPO_TPO

(3)

Diffraction protocol  (1)

Single wavelength

(1)

Diffraction radiation source type  (1)

Rotating anode

(2)

Diffraction source  (2)

RIGAKU RU200

(1)

RIGAKU RUH3R

(1)

Diffraction detector type  (1)

Image plate

(2)

Refinement software  (2)

CNS

(1)

X-PLOR

(1)

NMR software packages  (1)

X-PLOR

(1)

NMR Field Strength

400.0 - 500

(1)

500.0 - 600

(1)

600.0 - 700

(1)

Representative Structures

100%

95%

90%

70%

50%

40%

30%