Uniprot accession / id : P08883  OR   Uniprot accession / id : P20718
 
Filter by :
Entry Information
Entry status  (1)
REL
(4)
 
Experimental methods  (1)
X-ray diffraction
(4)
 
Authors  (15)
Fan Z
(4)
Liu S
(4)
Sun F
(4)
Tong L
(4)
Wang L
(4)
Wu L
(4)
Zhang H
(4)
Zhang K
(4)
Zhou Q
(3)
Li Q
(1)
Liu P
(1)
Lou J
(1)
Yang X
(1)
Zhang Y
(1)
Zhu P
(1)
 
Homo / hetero assembly  (2)
hetero
(2)
homo
(2)
 
Assembly composition  (2)
protein structure
(2)
protein/protein complex
(2)
 
Assembly polymer count  (2)
dimer
(2)
monomer
(2)
 
Resolution distribution
2.0 - 2.5
(2)
2.5 - 3
(2)
 
Release year distribution
2010 - 2015
(4)
 
Journal  (1)
J Immunol
(4)
 
Macromolecules
Organism superkingdom  (1)
Eukaryota
(4)
 
Organism name  (1)
Homo sapiens
(4)
 
Molecule name  (7)
CCP-X
(4)
CSP-C
(4)
CTSGL2
(4)
Cathepsin G-like 2
(4)
Cytotoxic T-lymphocyte proteinase
(4)
Cytotoxic serine protease C
(4)
Granzyme H
(4)
 
Molecule type  (1)
Protein
(4)
 
Gene names  (3)
CGL2
(4)
CTSGL2
(4)
GZMH
(4)
 
Interacting Molecules  (2)
Ac-PTSY-CMK inhibitor
(1)
PTSYAGDDSG
(1)
 
Interacting ligands  (2)
SO4 : SULFATE ION
(4)
CL : CHLORIDE ION
(1)
 
Function and Biology
Biological function  (4)
hydrolase activity
(4)
peptidase activity
(4)
serine-type endopeptidase activity
(4)
serine-type peptidase activity
(4)
 
Biological process  (4)
apoptotic process
(4)
killing of cells of another organism
(4)
protein maturation
(4)
proteolysis
(4)
 
Biological cell component  (4)
cytolytic granule
(4)
extracellular space
(4)
lysosome
(4)
membrane
(4)
 
Sequence and Structure classification
CATH class  (1)
Mainly Beta
(4)
 
CATH topology  (1)
Thrombin, subunit H
(4)
 
Pfam accession / name  (1)
PF00089 : Trypsin
(4)
 
Experimental Information
Diffraction protocol  (1)
Single wavelength
(4)
 
Diffraction radiation source type  (1)
Synchrotron
(4)
 
Diffraction source  (4)
PHOTON FACTORY BEAMLINE AR-NE3A
(1)
PHOTON FACTORY BEAMLINE BL-17A
(1)
PHOTON FACTORY BEAMLINE BL-5A
(1)
PHOTON FACTORY BEAMLINE BL-6A
(1)
 
Synchrotron site  (1)
Photon Factory
(4)
 
Diffraction detector type  (1)
CCD
(4)
 
Refinement software  (1)
REFMAC
(4)
 
Representative Structures
Representative Structures
100%
95%
90%
70%
50%
40%
30%
Entries 1 to 4 of 4
Entries 1 to 4 of 4
 Select all entries on this page
Crystal structure of human granzyme H with a peptidyl substrate
Wang L, Zhang K, Wu L, Tong L, Sun F, Fan Z
J Immunol (2012) [PMID: 22156497  ]
Source organisms: Synthetic construct, Homo sapiens  
Assembly composition: protein/protein complex
Bound ligands: SO4   
Assembly name: Granzyme H and peptide (Preferred)   search this complex
PDBe complex ID: PDB-CPX-149046 (Preferred)   search this ID
PDBe-KB: P20718   
X-ray diffraction
2.4Å resolution
Released: 28 Dec 2011
Model geometry
Fit model/data
3tjv
3tjv
3tjv
Crystal structure of human granzyme H with an inhibitor
Wang L, Zhang K, Wu L, Tong L, Sun F, Fan Z
J Immunol (2012) [PMID: 22156497  ]
Source organisms: Synthetic construct, Homo sapiens  
Assembly composition: protein/protein complex
Bound ligands: SO4   
Modified residues: TYW    ACE    ACE    TYW    0QE   
Assembly name: Granzyme H and peptide (Preferred)   search this complex
PDBe complex ID: PDB-CPX-149045 (Preferred)   search this ID
PDBe-KB: P20718   
X-ray diffraction
2.7Å resolution
Released: 28 Dec 2011
Model geometry
Fit model/data
3tju
3tju
3tju
Crystal structure of human granzyme H
Wang L, Zhang K, Wu L, Tong L, Sun F, Fan Z
J Immunol (2012) [PMID: 22156497  ]
Source organism: Homo sapiens  
Assembly composition: protein only structure
Bound ligands: SO4   
Assembly name: Granzyme H (Preferred)   search this complex
PDBe complex ID: PDB-CPX-149044 (Preferred)   search this ID
PDBe-KB: P20718   
X-ray diffraction
2.2Å resolution
Released: 28 Dec 2011
Model geometry
Fit model/data
3tk9
3tk9
3tk9
Crystal structure of active human granzyme H
Wang L, Li Q, Wu L, Zhang K, Tong L, Sun F, Fan Z
J Immunol (2013) [PMID: 23269243  ]
Source organism: Homo sapiens  
Assembly composition: protein only structure
Bound ligands: SO4    CL   
Assembly name: Granzyme H (Preferred)   search this complex
PDBe complex ID: PDB-CPX-149044 (Preferred)   search this ID
PDBe-KB: P20718   
X-ray diffraction
3Å resolution
Released: 16 Jan 2013
Model geometry
Fit model/data
4gaw
4gaw
4gaw
Entries 1 to 4 of 4
Entries 1 to 4 of 4