Uniprot accession / id : P08920  OR   Uniprot accession / id : P06729  OR   Uniprot accession / id : Q53F96
 
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Entry Information
Entry status  (1)
REL
(7)
 
Experimental methods  (2)
X-ray diffraction
(4)
Solution NMR
(3)
 
Authors  (38)
Reinherz EL
(4)
Wagner G
(4)
Arulanandam AR
(2)
Bravo J
(2)
Cardenes N
(2)
Cárdenes N
(2)
Deribe YL
(2)
Dikic I
(2)
Moncalian G
(2)
Moncalián G
(2)
Smolyar A
(2)
Spinola-Amilibia M
(2)
Spínola-Amilibia M
(2)
Wyss DF
(2)
Bodian DL
(1)
Choi JS
(1)
Davis SJ
(1)
Freund C
(1)
Harlos K
(1)
Jones EY
(1)
Kim M
(1)
Knoppers MH
(1)
Kuhne R
(1)
Kühne R
(1)
Li J
(1)
Liu J-H
(1)
Liu JH
(1)
Park S
(1)
Recny MA
(1)
Stuart DI
(1)
Sun ZJ
(1)
Sun ZY
(1)
Tan K
(1)
Wang J-H
(1)
Wang JH
(1)
Willis KJ
(1)
Withka JM
(1)
Yang H
(1)
 
Homo / hetero assembly  (2)
hetero
(4)
homo
(3)
 
Assembly composition  (2)
protein/protein complex
(4)
protein structure
(3)
 
Assembly polymer count  (2)
dimer
(4)
monomer
(3)
 
Resolution distribution
2.0 - 2.5
(2)
2.5 - 3
(1)
3.0 - 3.5
(1)
 
Release year distribution
1990 - 1995
(2)
1995 - 2000
(3)
2000 - 2005
(1)
2005 - 2010
(2)
 
Journal  (5)
J Biol Chem
(2)
Structure
(2)
Cell
(1)
EMBO J
(1)
Science
(1)
 
Macromolecules
Organism superkingdom  (1)
Eukaryota
(7)
 
Organism name  (1)
Homo sapiens
(7)
 
Molecule name  (6)
Erythrocyte receptor
(7)
LFA-2
(7)
LFA-3 receptor
(7)
Rosette receptor
(7)
T-cell surface antigen CD2
(7)
T-cell surface antigen T11/Leu-5
(7)
 
Molecule type  (1)
Protein
(7)
 
Gene names  (2)
CD2
(7)
SRBC
(7)
 
Interacting Molecules  (3)
CD2-associated protein
(2)
CD2 antigen cytoplasmic tail-binding protein 2
(1)
Lymphocyte function-associated antigen 3
(1)
 
Interacting ligands  (4)
NAG : 2-acetamido-2-deoxy-beta-D-glucopyranose
(2)
BMA : beta-D-mannopyranose
(1)
MAN : alpha-D-mannopyranose
(1)
NA : SODIUM ION
(1)
 
Function and Biology
Biological process  (1)
cell adhesion
(1)
 
Biological cell component  (1)
membrane
(1)
 
Sequence and Structure classification
SCOP fold  (1)
Immunoglobulin-like beta-sandwich
(4)
 
SCOP family  (2)
V set domains (antibody variable domain-like)
(4)
C2 set domains
(1)
 
CATH class  (1)
Mainly Beta
(4)
 
CATH topology  (1)
Immunoglobulin-like
(4)
 
Experimental Information
Diffraction protocol  (1)
Single wavelength
(4)
 
Diffraction radiation source type  (1)
Rotating anode
(3)
 
Representative Structures
Representative Structures
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Entries 1 to 7 of 7
Entries 1 to 7 of 7
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CD2BP2-GYF domain in complex with proline-rich CD2 tail segment peptide
Freund C, Kuhne R, Yang H, Park S, Reinherz EL, Wagner G
EMBO J (2002) [PMID: 12426371  ]
Source organism: Homo sapiens  
Assembly composition: protein/protein complex
Assembly name: T-cell surface antigen CD2 and CD2 antigen cytoplasmic tail-binding protein 2 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-131919 (Preferred)   search this ID
PDBe-KB: P06729    O95400   
Solution NMR
Released: 20 Nov 2002
Model geometry
Fit model/data
Data not analysed
1l2z
1l2z
1l2z
ATYPICAL POLYPROLINE RECOGNITION BY THE CMS N-TERMINAL SH3 DOMAIN. CMS:CD2 HETERODIMER
Moncalian G, Cardenes N, Deribe YL, Spinola-Amilibia M, Dikic I, Bravo J
J Biol Chem (2006) [PMID: 17020880  ]
Source organism: Homo sapiens  
Assembly composition: protein/protein complex
Assembly name: CD2-associated protein and T-cell surface antigen CD2 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-139165 (Preferred)   search this ID
PDBe-KB: P06729    Q9Y5K6   
X-ray diffraction
2.9Å resolution
Released: 6 Nov 2006
Model geometry
Fit model/data
2j7i
2j7i
2j7i
CRYSTAL STRUCTURE OF THE EXTRACELLULAR REGION OF THE HUMAN CELL ADHESION MOLECULE CD2 AT 2.5 ANGSTROMS RESOLUTION
Bodian DL, Jones EY, Harlos K, Stuart DI, Davis SJ
Structure (1994) [PMID: 7994575  ]
Source organism: Homo sapiens  
Assembly composition: protein only structure
Bound ligands: NAG    NA    NAG    NA   
Assembly name: T-cell surface antigen CD2 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-139163 (Preferred)   search this ID
PDBe-KB: P06729   
X-ray diffraction
2.5Å resolution
Released: 7 Feb 1995
Model geometry
Fit model/data
Data not deposited
1hnf
1hnf
1hnf
N-GLYCAN AND POLYPEPTIDE NMR SOLUTION STRUCTURES OF THE ADHESION DOMAIN OF HUMAN CD2
Wyss DF, Choi JS, Wagner G
Science (1995) [PMID: 7544493  ]
Source organism: Homo sapiens  
Assembly composition: protein only structure
Carbohydrate polymer components:
Molecule 1 - BMA(1), MAN(6), NAG(2)
Assembly name: T-cell surface antigen CD2 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-139163 (Preferred)   search this ID
PDBe-KB: P06729   
Solution NMR
Released: 8 Nov 1996
Model geometry
Fit model/data
Data not analysed
1gya
1gya
1gya
ATYPICAL POLYPROLINE RECOGNITION BY THE CMS N-TERMINAL SH3 DOMAIN. CMS:CD2 HETEROTRIMER
Moncalian G, Cardenes N, Deribe YL, Spinola-Amilibia M, Dikic I, Bravo J
J Biol Chem (2006) [PMID: 17020880  ]
Source organism: Homo sapiens  
Assembly composition: protein/protein complex
Assembly name: CD2-associated protein and T-cell surface antigen CD2 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-139165 (Preferred)   search this ID
PDBe-KB: P06729    Q9Y5K6   
X-ray diffraction
2.23Å resolution
Released: 11 Oct 2006
Model geometry
Fit model/data
2j6o
2j6o
2j6o
Structure of a Heterophilic Adhesion Complex Between the Human CD2 and CD58(LFA-3) Counter-Receptors
Wang J-H, Smolyar A, Tan K, Liu J-H, Kim M, Sun ZJ, Wagner G, Reinherz EL
Cell (1999) [PMID: 10380930  ]
Source organism: Homo sapiens  
Assembly composition: protein/protein complex
Assembly name: T-cell surface antigen CD2 and Lymphocyte function-associated antigen 3 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-139164 (Preferred)   search this ID
PDBe-KB: P06729    P19256   
X-ray diffraction
3.2Å resolution
Released: 29 Apr 1999
Model geometry
Fit model/data
Data not deposited
1qa9
1qa9
1qa9
STRUCTURE OF THE GLYCOSYLATED ADHESION DOMAIN OF HUMAN T LYMPHOCYTE GLYCOPROTEIN CD2
Wyss DF, Withka JM, Recny MA, Wagner G
Structure (1993) [PMID: 7915183  ]
Source organism: Homo sapiens  
Assembly composition: protein only structure
Assembly name: T-cell surface antigen CD2 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-139163 (Preferred)   search this ID
PDBe-KB: P06729   
Solution NMR
Released: 31 Jan 1994
Model geometry
Fit model/data
Data not deposited
1cdb
1cdb
1cdb
Entries 1 to 7 of 7
Entries 1 to 7 of 7