Entry status  (1)

REL

(27)

Experimental methods  (2)

X-ray diffraction

(26)

Solution NMR

(1)

Authors  (200)

Almo SC

(6)

Barman I

(5)

Bee C

(5)

Chau B

(5)

Lee PS

(5)

Rajpal A

(5)

Strop P

(5)

Korman AJ

(4)

Zhou A

(4)

Bonanno JB

(3)

Chang O

(3)

Davis SJ

(3)

Diong SJ

(3)

Fedorov AA

(3)

Gao H

(3)

Kumar A

(3)

Moon TM

(3)

Robison B

(3)

West S

(3)

Zhang F

(3)

Chai Y

(2)

Chew PV

(2)

Deyanova EG

(2)

Dollinger G

(2)

Engelhardt JJ

(2)

Evans EJ

(2)

Fedorov EV

(2)

Gao GF

(2)

Gilbert RJ

(2)

Gilbert RJC

(2)

Gudmundsson O

(2)

Ikemizu S

(2)

Lohre J

(2)

MacDonald KG

(2)

Massi E

(2)

Nandi P

(2)

Nathenson SG

(2)

Perkins P

(2)

Qi J

(2)

Schwartz JC

(2)

Shi Y

(2)

Sonnen AF

(2)

Sonnen AF-P

(2)

Sproul T

(2)

Stuart DI

(2)

Tan S

(2)

Thudium K

(2)

Wang J

(2)

Yu C

(2)

Zhang Y

(2)

Abbott WM

(1)

Abe R

(1)

Allen A

(1)

Almo S

(1)

Bajorath J

(1)

Baker D

(1)

Bell A

(1)

Bera AK

(1)

Cai H

(1)

Cao L

(1)

Carter L

(1)

Chae J

(1)

Chatwell L

(1)

Chen F

(1)

Chen V

(1)

Choi J

(1)

Constantine KL

(1)

Conventry B

(1)

Deshpande S

(1)

Dessailly BH

(1)

Devenport M

(1)

Dou F

(1)

Drabek D

(1)

Edman N

(1)

Erbe DV

(1)

Fenderson W

(1)

Feng H

(1)

Follows ER

(1)

Gan X

(1)

Garrett S

(1)

Garrett-Thomson SC

(1)

George R

(1)

Gerben SR

(1)

Ghosh A

(1)

Goreshnik I

(1)

Grosveld F

(1)

Guan J

(1)

Halabiya SF

(1)

He M

(1)

He Y

(1)

Heine P

(1)

Heo YS

(1)

Hicks DR

(1)

Hinck AP

(1)

Hinck CS

(1)

Hohlbaum A

(1)

Huang B

(1)

Iiyama M

(1)

Ito N

(1)

Janssens R

(1)

 

More...

Homo / hetero assembly  (2)

hetero

(21)

homo

(6)

Assembly composition  (2)

protein/protein complex

(21)

protein structure

(6)

Assembly polymer count  (4)

trimer

(11)

dimer

(9)

tetramer

(4)

monomer

(3)

Resolution distribution

1.0 - 1.5

(1)

1.5 - 2

(6)

2.0 - 2.5

(5)

2.5 - 3

(7)

3.0 - 3.5

(6)

3.5 - 4

(1)

Release year distribution

1995 - 2000

(2)

2000 - 2005

(4)

2005 - 2010

(3)

2010 - 2015

(3)

2015 - 2020

(10)

2020 - 2025

(14)

2025 - 2030

(3)

Journal  (14)

To be published

(7)

MAbs

(6)

Nature

(2)

Proc Natl Acad Sci U S A

(2)

Biochem J

(1)

Cell Discov

(1)

J Biol Chem

(1)

J Mol Biol

(1)

Mol Immunol

(1)

Nat Commun

(1)

Nat Struct Biol

(1)

Oncotarget

(1)

Science

(1)

bioRxiv

(1)

Organism superkingdom  (1)

Eukaryota

(27)

Organism name  (2)

Homo sapiens

(24)

Mus musculus

(3)

Molecule name  (3)

CTLA-4

(27)

Cytotoxic T-lymphocyte protein 4

(27)

Cytotoxic T-lymphocyte-associated antigen 4

(27)

Molecule type  (1)

Protein

(27)

Gene names  (4)

CD152

(22)

CTLA4

(22)

Cd152

(5)

Ctla4

(5)

Interacting Molecules  (28)

Fab heavy chain

(2)

Fab light chain

(2)

mipi.4 heavy chain

(2)

mipi.4 light chain

(2)

4003-1(VH)

(1)

9D9 heavy chain

(1)

9D9 light chain

(1)

A blocking anti-CTLA-4 nanobody (KN044)

(1)

A non-blocking CTLA-4 nanobody

(1)

AP-2 complex subunit mu

(1)

Antibody Ipilimumab heavy chain

(1)

Antibody Ipilimumab light chain

(1)

CTLA-4 binder

(1)

CTLA-4 nanobody

(1)

ENGINEERED HUMAN LIPOCALIN 2

(1)

Heavy chain

(1)

Ipilimumab Fab heavy chain

(1)

Ipilimumab Fab light chain

(1)

JS007-VH

(1)

JS007-VL

(1)

Light chain

(1)

Phosphatidylinositol 3-kinase regulatory subunit alpha

(1)

T-lymphocyte activation antigen CD80

(1)

T-lymphocyte activation antigen CD86

(1)

heavy chain

(1)

heavy chain of Fab

(1)

light chain

(1)

light chain of Fab

(1)

Interacting ligands  (9)

NAG : 2-acetamido-2-deoxy-beta-D-glucopyranose

(8)

FUC : alpha-L-fucopyranose

(3)

BMA : beta-D-mannopyranose

(2)

GOL : GLYCEROL

(2)

NA : SODIUM ION

(2)

CL : CHLORIDE ION

(1)

EDO : 1,2-ETHANEDIOL

(1)

FLC : CITRATE ANION

(1)

FUL : beta-L-fucopyranose

(1)

Biological process  (2)

immune response

(22)

regulation of T cell proliferation

(22)

Biological cell component  (1)

membrane

(22)

SCOP fold  (1)

Immunoglobulin-like beta-sandwich

(4)

SCOP family  (1)

V set domains (antibody variable domain-like)

(4)

CATH class  (1)

Mainly Beta

(12)

CATH topology  (1)

Immunoglobulin-like

(12)

Pfam accession / name  (1)

PF07686 : V-set

(25)

Diffraction protocol  (1)

Single wavelength

(26)

Diffraction radiation source type  (2)

Synchrotron

(25)

Rotating anode

(1)

Diffraction source  (16)

APS BEAMLINE 17-ID

(5)

SSRF BEAMLINE BL17U1

(3)

APS BEAMLINE 31-ID

(2)

NSLS BEAMLINE X9B

(2)

SSRF BEAMLINE BL17U

(2)

SSRF BEAMLINE BL19U1

(2)

ALS BEAMLINE 5.0.2

(1)

APS BEAMLINE 24-ID-E

(1)

BESSY BEAMLINE 14.1

(1)

DIAMOND BEAMLINE I04

(1)

NSLS-II BEAMLINE 17-ID-2

(1)

PAL/PLS BEAMLINE 5C (4A)

(1)

PHOTON FACTORY BEAMLINE BL-17A

(1)

RIGAKU

(1)

SRS BEAMLINE PX9.6

(1)

SSRF BEAMLINE BL18U1

(1)

Synchrotron site  (10)

APS

(8)

SSRF

(8)

NSLS

(2)

ALS

(1)

BESSY

(1)

Diamond

(1)

NSLS-II

(1)

PAL/PLS

(1)

Photon Factory

(1)

SRS

(1)

Diffraction detector type  (4)

Pixel

(14)

CCD

(10)

Area detector

(1)

Image plate

(1)

Refinement software  (5)

PHENIX

(16)

REFMAC

(6)

CNS

(4)

CNX

(1)

X-PLOR

(1)

NMR software packages  (1)

X-PLOR

(1)

NMR Field Strength

500.0 - 600

(1)

600.0 - 700

(1)

Representative Structures

100%

95%

90%

70%

50%

40%

30%