Entry status  (1)

REL

(7)

Experimental methods  (2)

X-ray diffraction

(6)

Solution NMR

(1)

Authors  (25)

Kuroki R

(3)

Okamoto T

(3)

Aritomi M

(2)

Honda S

(2)

Kunishima N

(2)

Miyafusa T

(2)

Morikawa K

(2)

Ota Y

(2)

Shibuya R

(2)

Cieslar C

(1)

Eisenberg D

(1)

Hill CP

(1)

Holak TA

(1)

Honjo E

(1)

Ishibashi M

(1)

Luers K

(1)

Lüers K

(1)

Maeda Y

(1)

Osslund TD

(1)

Ross A

(1)

Rudolph R

(1)

Tamada T

(1)

Tokunaga M

(1)

Zink T

(1)

Zink TW

(1)

Homo / hetero assembly  (2)

homo

(4)

hetero

(3)

Assembly composition  (2)

protein structure

(4)

protein/protein complex

(3)

Assembly polymer count  (3)

monomer

(3)

tetramer

(3)

trimer

(1)

Resolution distribution

1.5 - 2

(2)

2.0 - 2.5

(1)

2.5 - 3

(2)

3.0 - 3.5

(1)

Release year distribution

1990 - 1995

(2)

1995 - 2000

(2)

2000 - 2005

(2)

2005 - 2010

(1)

2015 - 2020

(2)

Journal  (5)

Nature

(2)

Proc Natl Acad Sci U S A

(2)

Biochem Biophys Res Commun

(1)

Biochemistry

(1)

FEBS J

(1)

Organism superkingdom  (1)

Eukaryota

(7)

Organism name  (1)

Homo sapiens

(7)

Molecule name  (3)

G-CSF

(7)

Granulocyte colony-stimulating factor

(7)

Pluripoietin

(7)

Molecule type  (1)

Protein

(7)

Gene names  (3)

C17orf33

(7)

CSF3

(7)

GCSF

(7)

Interacting Molecules  (1)

Granulocyte colony-stimulating factor receptor

(3)

Biological function  (5)

cytokine activity

(7)

enzyme binding

(7)

granulocyte colony-stimulating factor receptor binding

(7)

growth factor activity

(7)

signaling receptor binding

(7)

Biological process  (13)

cellular response to cytokine stimulus

(7)

cellular response to lipopolysaccharide

(7)

cytokine-mediated signaling pathway

(7)

granulocyte colony-stimulating factor signaling pathway

(7)

granulocyte differentiation

(7)

immune response

(7)

positive regulation of actin filament polymerization

(7)

positive regulation of cell population proliferation

(7)

positive regulation of myeloid cell differentiation

(7)

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

(7)

positive regulation of transcription by RNA polymerase II

(7)

regulation of actin filament organization

(7)

response to ethanol

(7)

Biological cell component  (4)

endocytic vesicle lumen

(7)

extracellular region

(7)

extracellular space

(7)

lysosomal lumen

(7)

SCOP fold  (1)

4-helical cytokines

(5)

SCOP family  (1)

Long-chain cytokines

(5)

CATH class  (1)

Mainly Alpha

(7)

CATH topology  (1)

Growth Hormone; Chain: A;

(7)

Pfam accession / name  (1)

PF16647 : GCSF

(7)

Diffraction protocol  (1)

Single wavelength

(5)

Diffraction radiation source type  (1)

Synchrotron

(5)

Diffraction source  (4)

PHOTON FACTORY BEAMLINE AR-NW12A

(2)

PHOTON FACTORY BEAMLINE BL-6B

(1)

SPRING-8 BEAMLINE BL38B1

(1)

SPRING-8 BEAMLINE BL41XU

(1)

Synchrotron site  (2)

Photon Factory

(3)

SPring-8

(2)

Diffraction detector type  (2)

CCD

(3)

Image plate

(2)

Refinement software  (2)

REFMAC

(4)

X-PLOR

(3)

NMR software packages  (1)

X-PLOR

(1)

Representative Structures

100%

95%

90%

70%

50%

40%

30%