Uniprot accession / id : P0DI97  OR   Uniprot accession / id : Q9CS84  OR   Uniprot accession / id : P58400  OR   Uniprot accession / id : Q9ULB1  OR   Uniprot accession / id : Q49A31  OR   Uniprot accession / id : A4FVB9
 
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Entry Information
Entry status  (1)
REL
(7)
 
Experimental methods  (1)
X-ray diffraction
(7)
 
Authors  (43)
Ahlsen G
(2)
Brunger AT
(2)
Choi UB
(2)
Honig B
(2)
Jin X
(2)
Katsamba PS
(2)
Koehnke J
(2)
Pfuetzner RA
(2)
Shapiro L
(2)
Sudhof TC
(2)
Südhof TC
(2)
White KI
(2)
Wilson SC
(2)
Zhou Q
(2)
Bahna F
(1)
Brasch J
(1)
Chen X
(1)
Focia P
(1)
Focia PJ
(1)
Fuentes EJ
(1)
Fukai S
(1)
Gakhar L
(1)
Goto-Ito S
(1)
He X
(1)
Hou T
(1)
Liu H
(1)
Maeda A
(1)
Maenaka K
(1)
Palmer AG
(1)
Saitoh T
(1)
Sato Y
(1)
Scheiffele P
(1)
Shim A
(1)
Shim AH
(1)
Shiroshima T
(1)
Sun YJ
(1)
Terada T
(1)
Trbovic N
(1)
Uemura T
(1)
Vendome J
(1)
Watanabe M
(1)
Yamagata A
(1)
Yoshida T
(1)
 
Homo / hetero assembly  (2)
hetero
(5)
homo
(2)
 
Assembly composition  (2)
protein/protein complex
(5)
protein structure
(2)
 
Assembly polymer count  (3)
dimer
(4)
monomer
(2)
tetramer
(1)
 
Resolution distribution
1.5 - 2
(4)
2.0 - 2.5
(1)
2.5 - 3
(1)
3.0 - 3.5
(1)
 
Release year distribution
2005 - 2010
(3)
2010 - 2015
(1)
2015 - 2020
(4)
2020 - 2025
(1)
 
Journal  (6)
EMBO J
(2)
Nat Commun
(1)
Nat Struct Mol Biol
(1)
Neuron
(1)
Structure
(1)
To be published
(1)
 
Macromolecules
Organism superkingdom  (1)
Eukaryota
(7)
 
Organism name  (2)
Mus musculus
(4)
Homo sapiens
(3)
 
Molecule name  (5)
Neurexin I-alpha
(5)
Neurexin-1
(5)
Neurexin-1-alpha
(5)
Neurexin I-beta
(2)
Neurexin-1-beta
(2)
 
Molecule type  (1)
Protein
(7)
 
Gene names  (4)
Kiaa0578
(4)
Nrxn1
(4)
NRXN1
(3)
KIAA0578
(1)
 
Interacting Molecules  (4)
Neurexophilin-1
(2)
Leucine-rich repeat transmembrane neuronal protein 2
(1)
Neuroligin-1
(1)
Peripheral plasma membrane protein CASK
(1)
 
Interacting ligands  (5)
CA : CALCIUM ION
(3)
NAG : 2-acetamido-2-deoxy-beta-D-glucopyranose
(2)
BMA : beta-D-mannopyranose
(1)
FUC : alpha-L-fucopyranose
(1)
PO4 : PHOSPHATE ION
(1)
 
Sequence and Structure classification
SCOP fold  (1)
Concanavalin A-like lectins/glucanases
(1)
 
SCOP family  (1)
Laminin G-like module
(1)
 
CATH class  (1)
Mainly Beta
(4)
 
CATH topology  (1)
Jelly Rolls
(4)
 
Pfam accession / name  (1)
PF02210 : Laminin_G_2
(6)
 
Experimental Information
Diffraction protocol  (1)
Single wavelength
(7)
 
Diffraction radiation source type  (1)
Synchrotron
(7)
 
Diffraction source  (6)
NSLS BEAMLINE X4C
(2)
ALS BEAMLINE 4.2.2
(1)
APS BEAMLINE 21-ID-D
(1)
APS BEAMLINE 24-ID-C
(1)
SPRING-8 BEAMLINE BL41XU
(1)
SSRL BEAMLINE BL12-2
(1)
 
Synchrotron site  (5)
APS
(2)
NSLS
(2)
ALS
(1)
SPring-8
(1)
SSRL
(1)
 
Diffraction detector type  (3)
CCD
(3)
Pixel
(3)
CMOS
(1)
 
Refinement software  (3)
PHENIX
(4)
REFMAC
(2)
CNS
(1)
 
Representative Structures
Representative Structures
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Entries 1 to 7 of 7
Entries 1 to 7 of 7
 Select all entries on this page
Crystal structure of human LRRTM2 in complex with Neurexin 1beta
Yamagata A, Fukai S
Nat Commun (2018) [PMID: 30262834  ]
Source organism: Homo sapiens  
Assembly composition: protein/protein complex
Bound ligands: CA    NAG    ZN    CA    ZN    NAG   
Carbohydrate polymer components:
Molecule 1 - FUC(1), NAG(2)
Assembly name: Neurexin-1-beta and Leucine-rich repeat transmembrane neuronal protein 2 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-128890 (Preferred)   search this ID
PDBe-KB: P58400    O43300    P58400   
X-ray diffraction
3.4Å resolution
Released: 10 Oct 2018
Model geometry
Fit model/data
5z8y
5z8y
5z8y
Crystal structure of the splice insert-free neurexin-1 LNS2 domain in complex with neurexophilin-1
Wilson SC, White KI, Zhou Q, Brunger AT
EMBO J (2019) [PMID: 31566781  ]
Assembly composition: protein/protein complex
Assembly name: Neurexophilin-1 and Neurexin-1 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-179009 (Preferred)   search this ID
PDBe-KB: Q9CS84    Q63366    Q9CS84   
X-ray diffraction
1.94Å resolution
Released: 9 Oct 2019
Model geometry
Data not analysed
Fit model/data
Data not analysed
6pnp
6pnp
6pnp
Crystal structure of a human calcium/calmodulin dependent serine protein kinase (CASK) PDZ domain in complex with Neurexin-1 peptide
Sun YJ, Gakhar L, Fuentes EJ
To be published
Source organism: Homo sapiens  
Assembly composition: protein/protein complex
Bound ligands: EDO   
Assembly name: Peripheral plasma membrane protein CASK and Neurexin-1 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-127212 (Preferred)   search this ID
PDBe-KB: Q9ULB1    O14936   
X-ray diffraction
1.86Å resolution
Released: 1 Jan 2020
Model geometry
Data not analysed
Fit model/data
Data not analysed
6nid
6nid
6nid
Crystal structure of the SS2A splice insert-containing neurexin-1 LNS2 domain in complex with neurexophilin-1
Wilson SC, White KI, Zhou Q, Brunger AT
EMBO J (2019) [PMID: 31566781  ]
Assembly composition: protein/protein complex
Assembly name: Neurexophilin-1 and Neurexin-1 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-179009 (Preferred)   search this ID
PDBe-KB: Q9CS84    Q63366    Q9CS84   
X-ray diffraction
1.947Å resolution
Released: 9 Oct 2019
Model geometry
Fit model/data
6pnq
6pnq
6pnq
Structure of mouse beta-neurexin 1
Koehnke J, Jin X, Shapiro L
Structure (2008) [PMID: 18334216  ]
Source organism: Mus musculus  
Assembly composition: protein only structure
Bound ligands: CA    CA   
Assembly name: Neurexin-1 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-190010 (Preferred)   search this ID
PDBe-KB: Q9CS84    Q9CS84   
X-ray diffraction
1.7Å resolution
Released: 25 Mar 2008
Model geometry
Fit model/data
3bod
3bod
3bod
Crystal structure of beta-neurexin 1 with the splice insert 4
Jin X, Shapiro L
Neuron (2010) [PMID: 20624592  ]
Source organism: Mus musculus  
Assembly composition: protein only structure
Bound ligands: PO4   
Carbohydrate polymer components:
Molecule 1 - BMA(1), NAG(2)
Assembly name: Neurexin-1 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-190010 (Preferred)   search this ID
PDBe-KB: Q9CS84   
X-ray diffraction
2.69Å resolution
Released: 28 Jul 2010
Model geometry
Fit model/data
3mw2
3mw2
3mw2
Crystal structure of a synaptic adhesion complex
Chen X, Liu H, Shim A, Focia P, He X
Nat Struct Mol Biol (2008) [PMID: 18084303  ]
Assembly composition: protein/protein complex
Bound ligands: CA    NAG    CA    NAG   
Carbohydrate polymer components:
Molecule 1 - NAG(2)
Assembly name: Neurexin-1-beta and Neuroligin-1 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-157679 (Preferred)   search this ID
PDBe-KB: P58400    P58400    Q99K10   
X-ray diffraction
2.4Å resolution
Released: 15 Jan 2008
Model geometry
Fit model/data
3b3q
3b3q
3b3q
Entries 1 to 7 of 7
Entries 1 to 7 of 7