Entry status  (1)

REL

(11)

Experimental methods  (2)

Electron Microscopy

(7)

X-ray diffraction

(4)

Authors  (52)

Bubeck D

(8)

Couves EC

(5)

Gardner S

(5)

Menny A

(4)

Morgan BP

(4)

Bickel JK

(3)

Stansfeld PJ

(3)

Tate EW

(3)

Voisin TB

(3)

Aleshin AE

(2)

Boyd CM

(2)

Brooks NJ

(2)

DiScipio RG

(2)

Discipio RG

(2)

Franc V

(2)

Heck AJR

(2)

Joseph AP

(2)

Liddington RC

(2)

Lukassen MV

(2)

Serna M

(2)

Stec B

(2)

Topf M

(2)

Ahasan M

(1)

Andersen GR

(1)

Baas F

(1)

Bankston LA

(1)

DiScipio R

(1)

Fluiter K

(1)

Forneris F

(1)

Gros P

(1)

Gytz Olesen H

(1)

Hadders MA

(1)

Hakobyan S

(1)

Johnson KK

(1)

Kuipers TB

(1)

Lea SM

(1)

Llorca O

(1)

Marquart JA

(1)

Mei H

(1)

Michailidou I

(1)

Olesen HG

(1)

Pangburn M

(1)

Pangburn MK

(1)

Roversi P

(1)

Ruizendaal P

(1)

Schraufstatter IU

(1)

Vreijling J

(1)

Wang Y

(1)

Zelek WM

(1)

Zhang Y

(1)

de Klein F

(1)

van Dijk M

(1)

Homo / hetero assembly  (2)

hetero

(10)

homo

(1)

Assembly composition  (2)

protein/protein complex

(10)

protein structure

(1)

Assembly polymer count  (8)

24-mer

(2)

dimer

(2)

nonamer

(2)

decamer

(1)

heptamer

(1)

monomer

(1)

octamer

(1)

tetramer

(1)

Resolution distribution

2.0 - 2.5

(1)

2.5 - 3

(2)

3.0 - 3.5

(4)

3.5 - 4

(1)

4.0 - 4.5

(1)

5.5 - 6

(2)

Release year distribution

2010 - 2015

(3)

2015 - 2020

(2)

2020 - 2025

(6)

Journal  (4)

Nat Commun

(7)

J Biol Chem

(2)

Cell Rep

(1)

J Innate Immun

(1)

Organism superkingdom  (2)

Eukaryota

(11)

Bacteria

(1)

Organism name  (2)

Homo sapiens

(11)

Escherichia coli

(1)

Molecule name  (29)

Complement component C6

(11)

C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4

(9)

C5a anaphylatoxin

(9)

Complement C5

(9)

Complement C5 alpha chain

(9)

Complement C5 alpha' chain

(9)

Complement C5 beta chain

(9)

Complement component 8 subunit alpha

(7)

Complement component 8 subunit beta

(7)

Complement component C7

(7)

Complement component C8 alpha chain

(7)

Complement component C8 beta chain

(7)

Complement component C8 gamma chain

(7)

Complement component C9

(6)

Complement component C9a

(6)

Complement component C9b

(6)

1F5 antigen

(3)

20 kDa homologous restriction factor

(3)

CD59 glycoprotein

(3)

HRF-20

(3)

HRF20

(3)

MAC-IP

(3)

MAC-inhibitory protein

(3)

MACIF

(3)

MEM43 antigen

(3)

MIRL

(3)

Membrane attack complex inhibition factor

(3)

Membrane inhibitor of reactive lysis

(3)

Protectin

(3)

Molecule type  (1)

Protein

(11)

Gene names  (14)

C6

(11)

C5

(9)

CPAMD4

(9)

C7

(7)

C8A

(7)

C8B

(7)

C8G

(7)

C9

(6)

CD59

(3)

MIC11

(3)

MIN1

(3)

MIN2

(3)

MIN3

(3)

MSK21

(3)

Interacting Molecules  (11)

Complement C5

(9)

Complement component C6

(9)

Complement component C7

(7)

Complement component C8 alpha chain

(7)

Complement component C8 beta chain

(7)

Complement component C8 gamma chain

(7)

Complement component C9

(6)

CD59 glycoprotein

(3)

CP010 heavy chain

(1)

CP010 light chain

(1)

kappa specific nanobody

(1)

Interacting ligands  (10)

NAG : 2-acetamido-2-deoxy-beta-D-glucopyranose

(9)

CA : CALCIUM ION

(5)

FUC : alpha-L-fucopyranose

(5)

MAN : alpha-D-mannopyranose

(5)

BMA : beta-D-mannopyranose

(4)

BGC : beta-D-glucopyranose

(2)

ACT : ACETATE ION

(1)

CD : CADMIUM ION

(1)

FUL : beta-L-fucopyranose

(1)

NA : SODIUM ION

(1)

Biological function  (7)

endopeptidase inhibitor activity

(9)

protein binding

(7)

chemokine activity

(5)

signaling receptor binding

(5)

complement binding

(4)

protein-containing complex binding

(4)

retinol binding

(4)

Biological process  (19)

complement activation

(10)

immune response

(10)

inflammatory response

(9)

complement activation, classical pathway

(7)

immune system process

(7)

in utero embryonic development

(7)

innate immune response

(7)

killing of cells of another organism

(7)

positive regulation of immune response

(7)

G protein-coupled receptor signaling pathway

(5)

cell chemotaxis

(5)

cell surface receptor signaling pathway

(5)

chemotaxis

(5)

complement activation, alternative pathway

(5)

negative regulation of macrophage chemotaxis

(5)

positive regulation of chemokine production

(5)

positive regulation of vascular endothelial growth factor production

(5)

cell killing

(4)

protein homooligomerization

(4)

Biological cell component  (9)

extracellular region

(10)

extracellular space

(10)

membrane attack complex

(10)

extracellular exosome

(7)

plasma membrane

(7)

blood microparticle

(4)

extracellular vesicle

(4)

membrane

(4)

other organism cell membrane

(4)

CATH class  (1)

Mainly Beta

(2)

CATH topology  (2)

Complement Module; domain 1

(2)

TSP-1 type 1 repeat

(2)

Pfam accession / name  (21)

PF00057 : Ldl_recept_a

(10)

PF00084 : Sushi

(10)

PF00090 : TSP_1

(10)

PF01823 : MACPF

(10)

PF21195 : C8A_B_C6_EGF-like

(10)

PF00207 : A2M

(9)

PF01759 : NTR

(9)

PF01835 : MG2

(9)

PF07677 : A2M_recep

(9)

PF07678 : TED_complement

(9)

PF07703 : A2M_BRD

(9)

PF17789 : MG4

(9)

PF17790 : MG1

(9)

PF17791 : MG3

(9)

PF21309 : C5_CUB

(9)

PF00061 : Lipocalin

(7)

PF18434 : Kazal_3

(7)

PF21284 : C7_FIM2_N

(7)

PF21330 : C7_KAZAL

(7)

PF01821 : ANATO

(6)

PF00021 : UPAR_LY6

(3)

Diffraction protocol  (1)

Single wavelength

(4)

Diffraction radiation source type  (1)

Synchrotron

(4)

Diffraction source  (4)

ESRF BEAMLINE ID29

(1)

MAX IV BEAMLINE BioMAX

(1)

SSRL BEAMLINE BL11-1

(1)

SSRL BEAMLINE BL9-2

(1)

Synchrotron site  (3)

SSRL

(2)

ESRF

(1)

MAX IV

(1)

Diffraction detector type  (2)

CCD

(2)

Pixel

(2)

Refinement software  (4)

PHENIX

(5)

REFMAC

(3)

BUSTER

(1)

phenix.real_space_refine

(1)

EM microscope model  (1)

FEI TITAN KRIOS

(7)

EM detector name  (4)

FEI FALCON II (4k x 4k)

(2)

GATAN K2 QUANTUM (4k x 4k)

(2)

GATAN K3 (6k x 4k)

(2)

FEI FALCON IV (4k x 4k)

(1)

Representative Structures

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