Entry status  (1)

REL

(38)

Experimental methods  (3)

Electron Microscopy

(29)

X-ray diffraction

(8)

Solution NMR

(1)

Authors  (121)

Blundell TL

(17)

Chaplin AK

(15)

Charbonnier JB

(15)

Ropars V

(15)

Chirgadze DY

(14)

Hardwick SW

(14)

Barboule N

(12)

Calsou P

(12)

Frit P

(12)

Meek K

(11)

Britton S

(9)

De Oliveira TM

(8)

Kefala Stavridi A

(7)

Kefala-Stavridi A

(7)

Bossaert M

(6)

Chen X

(6)

Gellert M

(6)

Gontier A

(6)

Legrand P

(6)

Liang S

(6)

Maia De Oliviera T

(6)

Pandurangan AP

(6)

Rothenberg E

(6)

Seif-El-Dahan M

(6)

Wang H

(6)

Yang W

(6)

Chen Y

(5)

Buehl CJ

(4)

Chen S

(4)

Cheung JC

(4)

Fox T

(4)

Goff NJ

(4)

He Y

(4)

Jiang J

(4)

Lee L

(4)

Lees-Miller SP

(4)

Naila T

(4)

Tomkinson AE

(4)

Xu X

(4)

de Val N

(4)

Andreani J

(3)

Baconnais S

(3)

Barbet-Massin E

(3)

Berger I

(3)

Bourand-Plantefol A

(3)

Comte A

(3)

Davey P

(3)

Delteil C

(3)

Drevet P

(3)

Guerois R

(3)

Hnizda A

(3)

Jonchhe S

(3)

Le Cam E

(3)

Modesti M

(3)

Morin V

(3)

Morten MJ

(3)

Nemoz C

(3)

Pitois A

(3)

Racca C

(3)

Rak A

(3)

Stavridi AK

(3)

Tadi S

(3)

Varela PF

(3)

Yin Y

(3)

Yu J

(3)

Arribas-Bosacoma R

(2)

Boskovic J

(2)

Cooper LR

(2)

Corpina RA

(2)

Escudero-Bravo P

(2)

Fernandez-Leiro R

(2)

Fishbain S

(2)

Goldberg J

(2)

Li J

(2)

Liu L

(2)

Llorca O

(2)

McKeown R

(2)

Oliver AW

(2)

Pearl LH

(2)

Rivera-Calzada A

(2)

Ruiz-Ramos A

(2)

Vogt A

(2)

Walker JR

(2)

Wang A

(2)

Ascher DB

(1)

Beckmann R

(1)

Chang CW

(1)

Chen DJ

(1)

Chen F

(1)

Choudhary JS

(1)

Douglas ME

(1)

Eickhoff P

(1)

Fisher CEL

(1)

Fontes MR

(1)

Fontes MRM

(1)

Guettler S

(1)

Hnízda A

(1)

Inian O

(1)

Kater L

(1)

Kobe B

(1)

 

More...

Homo / hetero assembly  (2)

hetero

(37)

homo

(1)

Assembly composition  (3)

DNA/protein complex

(31)

protein/protein complex

(6)

protein structure

(1)

Assembly polymer count  (12)

pentamer

(7)

heptamer

(5)

tetramer

(5)

dimer

(4)

hexamer

(4)

icosamer

(4)

octadecamer

(3)

decamer

(2)

22-mer

(1)

25-mer

(1)

heptadecamer

(1)

monomer

(1)

Resolution distribution

2.0 - 2.5

(2)

2.5 - 3

(10)

3.0 - 3.5

(6)

3.5 - 4

(6)

4.0 - 4.5

(4)

4.5 - 5

(3)

5.0 - 5.5

(1)

6.5 - 7

(1)

7.0 - 7.5

(1)

7.5 - 8

(1)

8.0 - 8.5

(1)

8.5 - 9

(1)

Release year distribution

2000 - 2005

(3)

2010 - 2015

(1)

2015 - 2020

(6)

2020 - 2025

(30)

2025 - 2030

(1)

Journal  (12)

Mol Cell

(8)

Sci Adv

(8)

Nat Struct Mol Biol

(7)

Nature

(4)

Nucleic Acids Res

(3)

Nat Commun

(2)

Cell Res

(1)

FEBS J

(1)

J Biol Chem

(1)

J Mol Biol

(1)

Structure

(1)

To be published

(1)

Organism superkingdom  (1)

Eukaryota

(38)

Organism name  (1)

Homo sapiens

(38)

Molecule name  (15)

5'-dRP lyase Ku70

(38)

5'-deoxyribose-5-phosphate lyase Ku70

(38)

70 kDa subunit of Ku antigen

(38)

ATP-dependent DNA helicase 2 subunit 1

(38)

ATP-dependent DNA helicase II 70 kDa subunit

(38)

CTC box-binding factor 75 kDa subunit

(38)

CTC75

(38)

CTCBF

(38)

DNA repair protein XRCC6

(38)

Ku70

(38)

Lupus Ku autoantigen protein p70

(38)

TLAA

(38)

Thyroid-lupus autoantigen

(38)

X-ray repair complementing defective repair in Chinese hamster cells 6

(38)

X-ray repair cross-complementing protein 6

(38)

Molecule type  (1)

Protein

(38)

Gene names  (2)

G22P1

(38)

XRCC6

(38)

Interacting Molecules  (47)

X-ray repair cross-complementing protein 5

(36)

DNA-dependent protein kinase catalytic subunit

(21)

Non-homologous end-joining factor 1

(12)

DNA ligase 4

(10)

DNA repair protein XRCC4

(10)

Protein PAXX

(8)

DNA (26-MER)

(7)

DNA (27-MER)

(6)

DNA (28-MER)

(5)

DNA (34-MER)

(5)

DNA (5'-D(*GP*CP*AP*TP*GP*CP*TP*CP*TP*AP*CP*TP*GP*CP*TP*TP*CP*GP*AP*TP*AP*TP*CP*G)-3')

(4)

DNA (25-MER)

(3)

DNA (30-MER)

(3)

DNA (31-MER)

(3)

DNA (5'-D(*AP*AP*GP*CP*AP*GP*TP*AP*GP*AP*GP*CP*A)-3')

(3)

DNA

(2)

DNA (21-MER)

(2)

DNA (24-MER)

(2)

DNA (5'-D(*GP*TP*TP*TP*TP*TP*AP*GP*TP*TP*TP*AP*TP*TP*GP*GP*GP*CP*GP*CP*G)-3')

(2)

Protein C10

(2)

Aprataxin and PNK-like factor

(1)

DNA (36-MER)

(1)

DNA (41-MER)

(1)

DNA (5'-D(*AP*AP*GP*CP*AP*GP*TP*AP*GP*AP*G)-3')

(1)

DNA (5'-D(*GP*TP*TP*TP*TP*TP*AP*GP*TP*TP*TP*AP*T)-3')

(1)

DNA (5'-D(P*AP*AP*AP*TP*AP*AP*AP*CP*TP*AP*AP*AP*AP*AP*C)-3')

(1)

DNA (5'-D(P*AP*AP*GP*CP*AP*GP*TP*AP*GP*AP*GP*CP*A)-3')

(1)

DNA (5'-D(P*AP*AP*TP*AP*AP*AP*CP*TP*AP*AP*AP*AP*AP*CP*TP*AP*TP*TP*AP*TP*TP*AP*TP*G)-3')

(1)

DNA (5'-D(P*AP*AP*TP*AP*AP*TP*AP*GP*TP*TP*TP*TP*TP*AP*GP*TP*TP*TP*AP*TP*TP*GP*GP*G)-3')

(1)

DNA (5'-D(P*CP*AP*AP*TP*GP*AP*AP*AP*CP*GP*GP*AP*AP*CP*AP*GP*TP*CP*AP*G)-3')

(1)

DNA (5'-D(P*CP*GP*AP*TP*AP*TP*CP*TP*AP*GP*AP*GP*GP*GP*AP*T)-3')

(1)

DNA (5'-D(P*CP*GP*AP*TP*AP*TP*CP*TP*AP*GP*AP*GP*GP*GP*AP*TP*C)-3')

(1)

DNA (5'-D(P*CP*GP*GP*AP*TP*CP*GP*AP*GP*GP*GP*CP*CP*CP*GP*AP*TP*AP*T)-3')

(1)

DNA (5'-D(P*GP*AP*TP*CP*CP*CP*TP*CP*TP*AP*GP*AP*TP*AP*T)-3')

(1)

DNA (5'-D(P*GP*CP*AP*TP*GP*CP*TP*CP*TP*AP*CP*TP*GP*CP*TP*TP*CP*GP*AP*TP*AP*TP*CP*G)-3')

(1)

DNA (5'-D(P*GP*GP*GP*CP*CP*CP*TP*CP*GP*AP*TP*CP*CP*G)-3')

(1)

DNA (5'-D(P*GP*TP*TP*CP*TP*TP*AP*GP*TP*AP*TP*AP*TP*A)-3')

(1)

DNA (5'-D(P*TP*AP*AP*TP*AP*AP*TP*AP*GP*TP*TP*TP*TP*TP*AP*GP*TP*TP*TP*AP*TP*TP*AP*G)-3')

(1)

DNA (5'-D(P*TP*AP*TP*AP*TP*AP*CP*TP*AP*AP*GP*AP*AP*C)-3')

(1)

DNA (5'-D(P*TP*CP*CP*CP*TP*CP*TP*AP*GP*AP*TP*AP*TP*C)-3')

(1)

Hairpin_1

(1)

Importin subunit alpha-1

(1)

PRKDC-Helix

(1)

PRKDC_HUMAN DNA-dependent protein kinase catalytic subunit -- Unknown region

(1)

Protein artemis

(1)

Telomeric repeat-binding factor 2-interacting protein 1

(1)

Unknown peptide

(1)

Interacting ligands  (2)

IHP : INOSITOL HEXAKISPHOSPHATE

(5)

SO4 : SULFATE ION

(3)

Biological function  (22)

DNA binding

(36)

DNA helicase activity

(36)

telomeric DNA binding

(36)

damaged DNA binding

(35)

5'-deoxyribose-5-phosphate lyase activity

(31)

ATP binding

(31)

ATP hydrolysis activity

(31)

ATP-dependent activity, acting on DNA

(31)

DNA end binding

(31)

RNA binding

(31)

catalytic activity

(31)

cyclin binding

(31)

double-stranded DNA binding

(31)

double-stranded telomeric DNA binding

(31)

helicase activity

(31)

hydrolase activity

(31)

lyase activity

(31)

nucleotide binding

(31)

protein binding

(31)

protein-containing complex binding

(31)

scaffold protein binding

(31)

transcription cis-regulatory region binding

(31)

Biological process  (20)

double-strand break repair via nonhomologous end joining

(36)

telomere maintenance

(36)

DNA damage response

(31)

DNA recombination

(31)

DNA repair

(31)

activation of innate immune response

(31)

cellular hyperosmotic salinity response

(31)

cellular response to X-ray

(31)

cellular response to gamma radiation

(31)

double-strand break repair via classical nonhomologous end joining

(31)

immune system process

(31)

innate immune response

(31)

negative regulation of DNA-templated transcription

(31)

negative regulation of macromolecule biosynthetic process

(31)

positive regulation of DNA-templated transcription

(31)

positive regulation of lymphocyte differentiation

(31)

positive regulation of protein kinase activity

(31)

positive regulation of transcription by RNA polymerase II

(31)

recombinational repair

(31)

regulation of smooth muscle cell proliferation

(31)

Biological cell component  (19)

Ku70:Ku80 complex

(36)

nucleus

(36)

DNA-dependent protein kinase complex

(31)

DNA-dependent protein kinase-DNA ligase 4 complex

(31)

chromosome

(31)

chromosome, telomeric region

(31)

cytoplasm

(31)

cytosol

(31)

extracellular region

(31)

ficolin-1-rich granule lumen

(31)

membrane

(31)

nonhomologous end joining complex

(31)

nuclear telomere cap complex

(31)

nucleolus

(31)

nucleoplasm

(31)

protein-DNA complex

(31)

protein-containing complex

(31)

secretory granule lumen

(31)

transcription regulator complex

(31)

SCOP fold  (3)

LEM/SAP HeH motif

(2)

SPOC domain-like

(2)

vWA-like

(2)

SCOP family  (3)

Ku70 subunit N-terminal domain

(2)

Ku70 subunit middle domain

(2)

SAP domain

(2)

CATH class  (4)

Mainly Alpha

(6)

Alpha Beta

(5)

Few Secondary Structures

(5)

Mainly Beta

(5)

CATH topology  (5)

Ku70, bridge and pillars

(5)

Ku70; Chain: A; Domain 2

(5)

Ku70; Chain: A; domain 4

(5)

Rossmann fold

(5)

Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1

(2)

Pfam accession / name  (4)

PF02735 : Ku

(36)

PF03730 : Ku_C

(36)

PF03731 : Ku_N

(36)

PF02037 : SAP

(32)

Diffraction protocol  (2)

Single wavelength

(8)

MAD

(1)

Diffraction radiation source type  (1)

Synchrotron

(8)

Diffraction source  (5)

SOLEIL BEAMLINE PROXIMA 2

(3)

SOLEIL BEAMLINE PROXIMA 1

(2)

LNLS BEAMLINE W01B-MX2

(1)

NSLS BEAMLINE X25

(1)

NSLS BEAMLINE X9A

(1)

Synchrotron site  (3)

SOLEIL

(5)

NSLS

(2)

LNLS

(1)

Diffraction detector type  (2)

Pixel

(5)

CCD

(3)

Refinement software  (5)

PHENIX

(21)

phenix.real_space_refine

(10)

BUSTER

(4)

CNS

(2)

REFMAC

(1)

Representative Structures

100%

95%

90%

70%

50%

40%

30%