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Entry Information
Entry status
(1)
Experimental methods
(2)
X-ray diffraction
(17)
Electron Microscopy
(4)
Authors
(104)
Pokutta S
(7)
Weis WI
(7)
Brooks AG
(5)
Rossjohn J
(5)
Saunders PM
(5)
Vivian JP
(5)
Wong SC
(5)
Barberena-Jonas C
(3)
Clemens EB
(3)
Davies J
(3)
Faoro C
(3)
Fernandez-Vina M
(3)
Font-Porterias N
(3)
Guethlein LA
(3)
Harrison GF
(3)
Hensen L
(3)
Ioannidis AG
(3)
Izard T
(3)
Kedzierska K
(3)
Kichula KM
(3)
Loh L
(3)
Mentzer AJ
(3)
Miller A
(3)
Montero-Martin G
(3)
Moreno-Estrada A
(3)
Nemat-Gorgani N
(3)
Norman PJ
(3)
Oppenheimer SJ
(3)
Parham P
(3)
Pomat W
(3)
Rangarajan ES
(3)
Sadeeq S
(3)
Tao S
(3)
Tong SYC
(3)
Widjaja J
(3)
Zhu F
(3)
Zhu S
(3)
Alushin GM
(2)
Bankston L
(2)
Bankston LA
(2)
Cadwell GW
(2)
Choi H-J
(2)
Deng Y
(2)
Ikura M
(2)
Illing PT
(2)
Ishiyama N
(2)
Liddington R
(2)
Liddington RC
(2)
MacLachlan BJ
(2)
Maclachlan B
(2)
Oates CVL
(2)
Purcell AW
(2)
Pymm P
(2)
Reynolds MJ
(2)
Yonemura S
(2)
Abbas YM
(1)
Abe K
(1)
Amano Y
(1)
Barford D
(1)
Barrick SK
(1)
Bueler SA
(1)
Dokurno P
(1)
Drees F
(1)
Dunn AR
(1)
Espinosa de Los Reyes S
(1)
Fernandez-Gonzalez R
(1)
Flozak AS
(1)
Fuller G
(1)
Gong R
(1)
Gottardi CJ
(1)
Hakoshima T
(1)
Hanein D
(1)
Hayashi H
(1)
Hirano Y
(1)
Kee YS
(1)
Kobb AB
(1)
Leckband DE
(1)
Leicher R
(1)
Li J
(1)
Liu S
(1)
Mei L
(1)
Nagar B
(1)
Nelson WJ
(1)
Nishikawa T
(1)
Rubinstein JL
(1)
Sarpal R
(1)
Smith EW
(1)
Sun X
(1)
Swift MF
(1)
Tajkhorshid E
(1)
Takai Y
(1)
Takeichi M
(1)
Tanaka N
(1)
Tepass U
(1)
Terekhova K
(1)
Tonks NK
(1)
Torres M
(1)
Umitsu M
(1)
Volkmann N
(1)
Wood MN
(1)
More...
Homo / hetero assembly
(2)
hetero
(14)
homo
(7)
Assembly composition
(2)
protein/protein complex
(14)
protein structure
(7)
Assembly polymer count
(7)
dimer
(10)
tetramer
(3)
dodecamer
(2)
monomer
(2)
trimer
(2)
heptamer
(1)
octamer
(1)
Resolution distribution
1.0 - 1.5
(2)
1.5 - 2
(3)
2.0 - 2.5
(6)
2.5 - 3
(4)
3.0 - 3.5
(2)
3.5 - 4
(2)
4.0 - 4.5
(1)
6.0 - 6.5
(1)
Release year distribution
1995 - 2000
(2)
2000 - 2005
(4)
2010 - 2015
(5)
2015 - 2020
(7)
2020 - 2025
(9)
Journal
(13)
Cell
(3)
J Biol Chem
(3)
Elife
(2)
Mol Cell
(2)
Proc Natl Acad Sci U S A
(2)
To be published
(2)
Commun Biol
(1)
EMBO J
(1)
Genes Cells
(1)
Nat Commun
(1)
Nat Struct Mol Biol
(1)
Sci Rep
(1)
bioRxiv
(1)
Macromolecules
Organism superkingdom
(1)
Eukaryota
(19)
Organism name
(3)
Mus musculus
(11)
Homo sapiens
(8)
synthetic construct
(2)
Molecule name
(6)
Alpha E-catenin
(21)
Catenin alpha-1
(21)
102 kDa cadherin-associated protein
(11)
CAP102
(11)
Cadherin-associated protein
(10)
Renal carcinoma antigen NY-REN-13
(10)
Molecule type
(1)
Protein
(21)
Gene names
(3)
Catna1
(11)
Ctnna1
(11)
CTNNA1
(10)
Interacting Molecules
(7)
Beta-2-microglobulin
(5)
Ig-like domain-containing protein
(5)
Actin, alpha skeletal muscle
(4)
Vinculin
(4)
Killer cell immunoglobulin-like receptor 3DL1
(3)
Afadin
(1)
Catenin beta-1
(1)
Interacting ligands
(7)
ACT : ACETATE ION
(1)
BR : BROMIDE ION
(1)
CA : CALCIUM ION
(1)
CL : CHLORIDE ION
(1)
MPD : (4S)-2-METHYL-2,4-PENTANEDIOL
(1)
PO4 : PHOSPHATE ION
(1)
SO4 : SULFATE ION
(1)
Function and Biology
Biological function
(10)
actin filament binding
(16)
cadherin binding
(13)
structural molecule activity
(8)
beta-catenin binding
(5)
gamma-catenin binding
(5)
identical protein binding
(5)
protein binding
(5)
protein-containing complex binding
(5)
vinculin binding
(5)
RNA binding
(3)
Biological process
(29)
cell adhesion
(16)
apical junction assembly
(5)
apoptotic process
(5)
axon regeneration
(5)
cell motility
(5)
cellular response to indole-3-methanol
(5)
epithelial cell-cell adhesion
(5)
establishment or maintenance of cell polarity
(5)
extrinsic apoptotic signaling pathway in absence of ligand
(5)
gap junction assembly
(5)
integrin-mediated signaling pathway
(5)
male gonad development
(5)
negative regulation of apoptotic process
(5)
negative regulation of cell motility
(5)
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
(5)
negative regulation of integrin-mediated signaling pathway
(5)
negative regulation of neuroblast proliferation
(5)
negative regulation of protein localization to nucleus
(5)
neuroblast proliferation
(5)
odontogenesis of dentin-containing tooth
(5)
ovarian follicle development
(5)
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
(5)
positive regulation of smoothened signaling pathway
(5)
protein localization
(5)
regulation of cell population proliferation
(5)
response to estrogen
(5)
smoothened signaling pathway
(5)
cell migration
(3)
cell-cell adhesion
(3)
Representative Structures
Representative Structures
Entries
Macromolecules
Compounds
Protein families
Entries 1 to 10 of 21
Select all entries on this page
mouse aE-catenin 82-883
Pokutta S, Weis WI
Sci Rep
(2019)
[PMID: 31653927 ]
Source organism: Mus musculus
Assembly composition: protein only structure
Assembly name:
Catenin alpha-1
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-150678 (Preferred)
search this ID

Crystal Structure of the complex between the vinculin D1 domain and alphaE-catenin
Hirano Y, Hakoshima T
Genes Cells
(2018)
[PMID: 29542234 ]
Source organism: Mus musculus
Assembly composition: protein/protein complex
Assembly name:
Catenin alpha-1 and Vinculin
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-150677 (Preferred)
search this ID
Crystal structure of the alpha-E-catenin actin-binding domain
Ishiyama N, Ikura M
Nat Commun
(2018)
[PMID: 30504777 ]
Source organism: Mus musculus
Assembly composition: protein only structure
Assembly name:
Catenin alpha-1
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-150678 (Preferred)
search this ID

F-actin binding interface of alpha-E-catenin ABD (cadherin-catenin complex) and afadin
Gong R, Reynolds MJ, Alushin GM
bioRxiv
(2024)
[PMID: 39415991 ]
Source organisms: Gallus gallus , Mus musculus
Assembly composition: protein/protein complex
PDBe complex ID:
PDB-CPX-280554 (Preferred)
search this ID
KIR3DL1*086 in complex with HLA-B*57:03 presenting the AW10 peptide
Faoro C, Rossjohn J
Cell
(2024)
[PMID: 39476840 ]
Source organism: Homo sapiens
Assembly composition: protein/protein complex
PDBe complex ID:
PDB-CPX-282738 (Preferred)
search this ID
KIR3DL1*001 in complex with HLA-B*57:03 presenting the AW10 peptide
Faoro C, Rossjohn J
Cell
(2024)
[PMID: 39476840 ]
Source organism: Homo sapiens
Assembly composition: protein/protein complex
PDBe complex ID:
PDB-CPX-282738 (Preferred)
search this ID
KIR3DL1*114 in complex with HLA-B*57:03 presenting the AW10 peptide
Faoro C, Rossjohn J
Cell
(2024)
[PMID: 39476840 ]
Source organism: Homo sapiens
Assembly composition: protein/protein complex
PDBe complex ID:
PDB-CPX-282738 (Preferred)
search this ID
Alpha-E-catenin ABD-F-actin complex
Mei L, Alushin GM
Elife
(2020)
[PMID: 32969337 ]
Source organisms: Gallus gallus , Homo sapiens
Assembly composition: protein/protein complex
Assembly name:
Actin, alpha skeletal muscle and Catenin alpha-1
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-152829 (Preferred)
search this ID
CRYSTAL STRUCTURE OF THE ALPHA-CATENIN DIMERIZATION DOMAIN
Pokutta S, Weis WI
Mol Cell
(2000)
[PMID: 10882138 ]
Source organism: Mus musculus
Assembly composition: protein only structure
Assembly name:
Catenin alpha-1
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-150678 (Preferred)
search this ID

Cryogenic electron microscopy 3D map of F-actin bound by human dimeric alpha-catenin
Rangarajan ES, Smith EW, Izard T
Commun Biol
(2023)
[PMID: 36928388 ]
Source organisms: Oryctolagus cuniculus , Homo sapiens
Assembly composition: protein/protein complex
Assembly name:
Actin, alpha skeletal muscle and Catenin alpha-1
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-152830 (Preferred)
search this ID
Entries 1 to 10 of 21