Entry status  (1)

REL

(2)

Experimental methods  (1)

X-ray diffraction

(2)

Authors  (4)

Adachi H

(2)

Nitanai Y

(2)

Satow Y

(2)

Tsujimoto M

(2)

Homo / hetero assembly  (1)

homo

(2)

Assembly composition  (1)

protein structure

(2)

Assembly polymer count  (1)

dimer

(2)

Resolution distribution

1.5 - 2

(1)

2.0 - 2.5

(1)

Release year distribution

2000 - 2005

(2)

Journal  (1)

J Mol Biol

(2)

Organism superkingdom  (1)

Eukaryota

(2)

Organism name  (1)

Homo sapiens

(2)

Molecule name  (6)

Beta-lactamase

(2)

Dehydropeptidase-I

(2)

Dipeptidase 1

(2)

Microsomal dipeptidase

(2)

Renal dipeptidase

(2)

hRDP

(2)

Molecule type  (1)

Protein

(2)

Gene names  (3)

DPEP1

(2)

MDP

(2)

RDP

(2)

Interacting ligands  (3)

NAG : 2-acetamido-2-deoxy-beta-D-glucopyranose

(2)

ZN : ZINC ION

(2)

CIL : CILASTATIN

(1)

EC number / name  (2)

3.4.13.19 : Membrane dipeptidase

(2)

3.5.2.6 : Beta-lactamase

(2)

Biological function  (12)

GPI anchor binding

(2)

beta-lactamase activity

(2)

dipeptidase activity

(2)

hydrolase activity

(2)

metal ion binding

(2)

metallodipeptidase activity

(2)

metalloexopeptidase activity

(2)

metallopeptidase activity

(2)

modified amino acid binding

(2)

peptidase activity

(2)

protein binding

(2)

zinc ion binding

(2)

Biological process  (14)

antibiotic metabolic process

(2)

cellular response to calcium ion

(2)

cellular response to nitric oxide

(2)

glutathione catabolic process

(2)

glutathione metabolic process

(2)

homocysteine metabolic process

(2)

inflammatory response

(2)

lactam catabolic process

(2)

leukotriene D4 catabolic process

(2)

leukotriene metabolic process

(2)

lipid metabolic process

(2)

negative regulation of cell migration

(2)

neutrophil chemotaxis

(2)

proteolysis

(2)

Biological cell component  (11)

apical part of cell

(2)

apical plasma membrane

(2)

cell junction

(2)

cell projection

(2)

extracellular exosome

(2)

extracellular space

(2)

membrane

(2)

microvillus membrane

(2)

nucleoplasm

(2)

plasma membrane

(2)

side of membrane

(2)

SCOP fold  (1)

TIM beta/alpha-barrel

(2)

SCOP family  (1)

Renal dipeptidase

(2)

CATH class  (1)

Alpha Beta

(2)

CATH topology  (1)

TIM Barrel

(2)

Pfam accession / name  (1)

PF01244 : Peptidase_M19

(2)

Diffraction protocol  (1)

Single wavelength

(2)

Diffraction radiation source type  (1)

Rotating anode

(2)

Diffraction source  (1)

RIGAKU RU300

(2)

Diffraction detector type  (1)

Image plate

(2)

Refinement software  (1)

X-PLOR

(2)

Representative Structures

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